Millifolides A–C. New 1,10-Seco-guaianolides from the Flowers of Achillea millefolium

2012 ◽  
Vol 67 (5) ◽  
pp. 438-446 ◽  
Author(s):  
Yong Li ◽  
Zhi-Yu Ni ◽  
Meng-Chu Zhu ◽  
Kai Zhang ◽  
Yi-Bing Wu ◽  
...  

Ten 1,10-secoguaianolides were isolated from the flowers of Achillea millefolium. Their structures were determined on the basis of spectroscopic methods. Three of them (millifolides A-C) including two dimeric sesquiterpenoids exhibit new skeletons. Seco-tanapartholide A exhibited moderate cell growth inhibitory activity against the human cancer cell line MCF7WT (IC50 = 5.51 μm) in vitro.

2010 ◽  
Vol 20 (17) ◽  
pp. 5353-5356 ◽  
Author(s):  
Françoise Borcard ◽  
Matthias Baud ◽  
Claudia Bello ◽  
Giovanna Dal Bello ◽  
Francesco Grossi ◽  
...  

2008 ◽  
Vol 18 (24) ◽  
pp. 6451-6453 ◽  
Author(s):  
Naoto Kojima ◽  
Hiromi Hayashi ◽  
Satoshi Suzuki ◽  
Hiroaki Tominaga ◽  
Naoyoshi Maezaki ◽  
...  

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