Oro-Pharyngeal Carriage And Antimicrobial Susceptibility Of Streptococcus Pneumoniae From Healthy Children

10.5580/2cda ◽  
2013 ◽  
Vol 11 (1) ◽  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Antimicrobial Susceptibility ◽  
Healthy Children

scholarly journals Factors Associated with Streptococcus pneumoniae Nasopharyngeal Carriage and Antimicrobial Susceptibility among Children Under the Age of 5 Years in the Southwestern Colombia

2021 ◽  
Author(s):  
Gustavo Gámez ◽  
Juan Pablo Rojas ◽  
Santiago Cardona ◽  
Juan David Castillo Noreña ◽  
María Alejandra Palacio ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Antimicrobial Susceptibility ◽  
Indigenous Communities ◽  
Cross Sectional Study ◽  
Nasopharyngeal Swab ◽  
Nasopharyngeal Carriage ◽  
Cross Sectional ◽  
Benzyl Penicillin ◽  
Factors Associated ◽  
Pediatric Outpatients

Abstract Objective This work aims to evaluate the factors associated with Streptococcus pneumoniae nasopharyngeal colonization and antimicrobial susceptibility among pediatric outpatients in southwestern Colombia, 2019. Methods A cross-sectional study was performed using survey-based interviews and the collection of nasopharyngeal-swab specimens for microbiological characterization and antimicrobial susceptibility testing. Logistic regression analyses were performed for factors associated with nasopharyngeal carriage. Results A total of 452 children under the age of 5 years were examined in which 41.8% carried S. pneumoniae. Higher pneumococcal carriage frequencies were observed among participants aged <2 years and in individuals belonging to indigenous communities, which were lacking established pneumococcal-conjugated vaccine-10 immunization schemes. Additionally, children attending childcare institutions were also highly colonized by pneumococci. S. pneumoniae showed 57.7% nonsusceptibility to benzyl-penicillin (meningitis-cut); 45.5% intermediate-sensitivity to benzyl-penicillin (oral-cut) and 21.7% to cefotaxime; and resistance to erythromycin (40.7%), tetracycline (36.0%), trimethoprim/sulfamethoxazole (24.9%), clindamycin (24.3%), and ceftriaxone (27.0%). Conclusion The 41.8% of participants carrying S. pneumoniae show a scenario with the presence of multidrug and extensively drug-resistant strains, which constitutes important reservoirs of bacterial transmission by children aged <5 years in Colombia, leading to an onset of pneumococcal diseases. Hence, there is an urgent need to expand conjugate pneumococcal immunization in the community and ensure compliance with established immunization schedules.

scholarly journals Trends in Antimicrobial Susceptibility of Streptococcus pneumoniae in the Tohoku District of Japan: A Longitudinal Analysis from 1998 to 2007

2010 ◽  
Vol 220 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Kazumasa Suzuki ◽  
Katsushi Nishimaki ◽  
Kaori Okuyama ◽  
Tadashi Katoh ◽  
Minoru Yasujima ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Longitudinal Analysis ◽  
Antimicrobial Susceptibility

scholarly journals Invasive isolates of Streptococcus pneumoniae in Serbia: Antimicrobial susceptibility and serotypes

2013 ◽  
Vol 141 (1-2) ◽  
pp. 48-53 ◽  
Author(s):  
Ina Gajic ◽  
Vera Mijac ◽  
Lazar Ranin ◽  
Dragana Andjelkovic ◽  
Miroslava Radicevic ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Invasive Pneumococcal Disease ◽  
Antimicrobial Susceptibility ◽  
Pneumococcal Disease ◽  
Medical Problem ◽  
Resistance Rate ◽  
Reference Laboratory ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
Resistance Rates

Introduction. Streptococcus pneumoniae is one of the leading causes of bacterial meningitis and sepsis. Invasive pneumococcal disease is a significant medical problem worldwide, particularly in children, due to a huge increase of pneumococcal resistance to antibiotics. Objective. The aim of the study was to investigate the antimicrobial susceptibility pattern of invasive pneumococcal isolates, as well as to determine whether decreased S. pneumoniae susceptibility to antibiotics was related to a particular serotype. Methods. Antimicrobial susceptibility to 19 antibiotics was determined in 58 invasive pneumococcal strains that were collected from seven regional centers during the period July 2009 to February 2011 in the National Reference Laboratory for streptococci and pneumococci. Results. The overall nonsusceptibility rate to penicillin was detected in 34% of pneumococcal isolates and to erythromycin in 36%. Higher resistance rates were observed among children than among adults. Penicillin resistance rate was 65% in children versus 22% in adults, while erythromycin nonsusceptibility rate was 47% in children versus 32% in adults. Co-resistance to penicillin and erythromycin was detected in 21% strains, mostly isolated from children. Multiresistance was found in one third of isolates. All strains were susceptible to vancomycin, linezolid, fluoroquinolones, telithromycin and rifampicin, while 23 (40%) isolates were susceptible to all tested antibiotics. The most common resistant serotypes were 19F and 14. Conclusion. The study has revealed that penicillin and macrolide resistance among invasive pneumococcal isolates is very high in Serbia. This emphasizes the need for continuous monitoring for invasive pneumococcal disease to document the serotype distribution and antimicrobial susceptibility pattern.

scholarly journals Serotype Distribution, Antimicrobial Susceptibility, and Molecular Epidemiology of Streptococcus pneumoniae Isolated from Children in Shanghai, China

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142892 ◽  
Author(s):  
Fen Pan ◽  
Lizhong Han ◽  
Weichun Huang ◽  
Jin Tang ◽  
Shuzhen Xiao ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Molecular Epidemiology ◽  
Antimicrobial Susceptibility ◽  
Serotype Distribution

scholarly journals Streptococcus pneumoniae isolates in healthy children attending day-care centers in 12 states in Mexico

2007 ◽  
Vol 49 (4) ◽  
pp. 249-255 ◽  
Author(s):  
Luz Elena Espinosa-de los Monteros ◽  
Verónica Jiménez-Rojas ◽  
Felipe Aguilar-Ituarte ◽  
Miguel Cashat-Cruz ◽  
Alfonso Reyes-López ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Day Care ◽  
Healthy Children ◽  
Day Care Centers
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