scholarly journals Antioxidant and detoxycative mechanisms in central nervous system

2020 ◽  
Vol 74 ◽  
pp. 1-11
Author(s):  
Marzena Gutowicz
Keyword(s):  
Hydrogen Peroxide ◽  
Glutathione Transferase ◽  
Whole Body ◽  
Organic Peroxides ◽  
Antioxidants Activity ◽  
Cell Components ◽  
Nonenzymatic Antioxidants ◽  
Numerous Data ◽  
Small Change ◽  
The Many

Since the brain contains a large amount of polyunsaturated fatty acids, consumes up to 20% of oxygen used by the whole body and exhibits low antioxidants activity, it seems to be especially vulnerable to oxidative stress. The most important antioxidant enzymes are superoxide dismutase (SOD), which catalyze the dismutation of superoxide anion to hydrogen peroxide, catalase (CAT), which converts toxic hydrogen peroxide to water and oxygen, and glutathione peroxidase (Se-GSHPx), which reduces hydrogen peroxide and organic peroxides with glutathione as the cofactor. Among other detoxifying enzymes, the most significant is glutathione transferase (GST), which shows detoksyvarious catalytic activities allowing for removal of xenobiotics, reducing organic peroxides and oxidized cell components. One of the most important brain nonenzymatic antioxidants is reduced glutathione (GSH), which (individually or in cooperation with peroxidases) participates in the reduction of free radicals, repair of oxidative damage and the regeneration of other antioxidants, such as ascorbate or tocopherol. Glutathione as a cosubstrate of glutathione transferase scavenges toxic electrophilic compounds. Although the etiology of the major neurodegenerative diseases are unknown, numerous data suggest that reactive oxygen species play an important role. Even a small change in the level of antioxidants can leads to the many disorders in the CNS.

Integrative Sleep Medicine

2021 ◽  
Keyword(s):  
Circadian Rhythm ◽  
Sleep Disorders ◽  
Health Care Providers ◽  
Sleep Disturbances ◽  
Well Being ◽  
Sleep Medicine ◽  
Whole Body ◽  
Care Providers ◽  
Obstructive Sleep ◽  
The Many

Sleep is one of the key underpinnings of human health, yet sleep disturbances and impaired sleep are rampant in modern life. Healthy sleep is a whole-body process impacted by circadian rhythm, daily activities, and emotional well-being, among others. When properly aligned, these work in concert to produce restorative and refreshing sleep. When not in balance, however, sleep disorders result. Yet too often, the approach to treatment of sleep disorders is compartmentalized, failing to recognize all of the complex interactions that are involved. This text offers a comprehensive approach to sleep and sleep disorders by delineating the many factors that interplay into healthy sleep. Health care providers can learn how to better manage their patients with sleep disorders by integrating complementary and conventional approaches. Using an evidence-based approach throughout, this book describes the basics of normal sleep then delves into the foundations of integrative sleep medicine, including the circadian rhythm, mind/body-sleep connection, light, dreaming, the gastrointestinal system, and botanicals/supplements. Specific sleep issues and disorders are then addressed from an integrative perspective, including insomnia, obstructive sleep apnea, sleep related movement disorders, and parasomnias.

scholarly journals Professor Josip Ubl's contribution to the development of veterinary medicine in Croatia

2001 ◽  
Vol 46 (No. 6) ◽  
pp. 175-180
Author(s):  
V. Bajt V ◽  
G. Gračner G ◽  
A. Škrobonja
Keyword(s):  
Veterinary Medicine ◽  
Social Work ◽  
Animal Husbandry ◽  
Cultural Development ◽  
Primary And Secondary Education ◽  
History Of ◽  
Numerous Data ◽  
The Many ◽  
Outstanding Teacher ◽  
Assistant Lecturer

Numerous data point to the fact that Czech people played an important role in the cultural development of Croatia. Professor Josip Ubl was one of the many outstanding Czech veterinarians who greatly contributed to the Croatian veterinary medicine. Prof. Josip Ubl was born on the 4th April 1844 in Chudenice, in the Plzeň district. He descended from a respectable family, which highly influenced his schooling. He finished his primary and secondary education at his birthplace. He graduated from the k. u. k. Militär-Thierartznei-Institute in Vienna in 1867. Prof. Josip Ubl first worked as an assistant lecturer and as a professor of animal husbandry and veterinary medicine at the School of Farming and Farming Crafts in Doubravice near Loštice and Mohelnice in Moravia. Later on he was appointed a teacher of veterinary medicine, animal husbandry, anatomy and zoology at the Kraljevsko gospodarsko-šumarsko učilište i ratarnica (Royal School of Farming and Forestry) in Križevci in Croatia. He was an exceptionally prolific writer and wrote seven veterinary manuals. Besides being an outstanding teacher he was also engaged in social work and was awarded for his contribution to this field of work several times. As the author of the first veterinary works in Croatian language and the creator of the Croatian veterinary terminology he has gained a prominent place in the history of Croatian veterinary medicine.

Analysis of Acetone Peroxide Premixes for Bleaching and Maturing Flour

1964 ◽  
Vol 47 (2) ◽  
pp. 363-366
Author(s):  
James T Taylor
Keyword(s):  
Hydrogen Peroxide ◽  
Qualitative Method ◽  
Collaborative Study ◽  
Organic Peroxides ◽  
Dilute Sulfuric Acid ◽  
Quantitative Analyses ◽  
Single Determination ◽  
Acetone Peroxide ◽  
Qualitative Analyses

Abstract A quantitative and a qualitative method for the determination of acetone peroxides were subjected to collaborative study. Quantitative analyses are based upon liberation and titration of hydrogen peroxide from acyclic peroxides and hydroperoxides by dilute sulfuric acid and standardized potassium permanganate, respectively. Single determination of 6 samples (varying in per cent levels of peroxide equivalent) each of baking premixes and milling premixes produced very good collaborative results. Qualitative analyses, achieved by comparing infrared spectra of acetone-extracted organic peroxides with acetone-extracted organic peroxides from a reference premix, gave peaks characteristic of the premixes. No interferences were seen from various starch blanks. Both the quantitative and the qualitative methods are recommended for adoption as official, first action.

Effect of exogenous hydrogen peroxide on enzymatic and nonenzymatic antioxidants in leaves of young pea plants treated with paraquat

2008 ◽  
Vol 57 (2) ◽  
pp. 193-202 ◽  
Author(s):  
Irina Moskova ◽  
Dessislava Todorova ◽  
Vera Alexieva ◽  
Sergei Ivanov ◽  
Iskren Sergiev
Keyword(s):  
Hydrogen Peroxide ◽  
Nonenzymatic Antioxidants

ELOQUENT ACTION: THE BODY AND MEANING IN EARLY COMMEDIA DELL'ARTE

2009 ◽  
Vol 50 (2) ◽  
pp. 251-315 ◽  
Author(s):  
Matthew Buckley
Keyword(s):  
Facial Expression ◽  
Human Nature ◽  
External Action ◽  
The Body ◽  
Whole Body ◽  
Commedia Dell'arte ◽  
General Terms ◽  
The World ◽  
The Many ◽  
Common Character

One of the things that strikes one most forcibly in surviving images of early commedia dell'arte is its enigmatic physicality, the manner in which its actors everywhere adopt postures and make gestures that seem not merely emphatic and exaggerated but almost hieroglyphic, full of some additional implication, laden with a figural and emblematic resonance that we sense but no longer see. In general terms, this quality is easily understood, as the body clearly served in commedia as a complex and polyvalent instrument of expression. Its gestures and movements were, as in all theatre, indexically linked to dramatic action, and they also served, as in much masked drama, as surrogates for the facial expression of affect, in that the movements and aspects of the whole body were enlisted to articulate the motions and mien of a veiled face and to overcome or play upon the sensation of estranged speech produced by the half-mask's bifurcation of the visage. Moreover, in a manner less familiar but illustrated well in Fig. 1, these movements and aspects also functioned as expressions in their own right, not articulating the affect or expression attendant upon immediate speech or situation or delineating the lines of external action but signaling the many impulses and various appetites of the world, the varied aspects of all persons and of the body itself, and invoking at times as their implicatory context human nature, common character, and identity rather than situation, attitude, or emotion.

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