Model of the Fractionation Process of Three- and Four-Component Biological Mixtures in the Gravity Field

2020 ◽  
Vol 69 (3) ◽  
pp. 35-57
Author(s):  
Andrzej Górka

The publication describes a simplified method of evaluation of basic parameters of the fractionation process in the gravity field of three- and four-component biological mixtures having physical parame-ters similar to peripheral blood. The description of the method contains the balance of masses and forc-es imposing independent movement of microparticles of different shape in the base fluid matrix. It was also assumed that the biological mixture as an uncompressible quasi-homogeneous liquid can be de-scribed using the basic laws of hydrodynamics. The presented method of evaluation of basic parame-ters of the fractionation process, in relation to complex biological mixtures, together with calculation examples, is a prelude to the extended peripheral blood test within the sedimentation rate of erythro-cytes OB (ESR). Keywords: fractionation of biological mixtures, sedimentation of blood components, mixture fractionation process model, a peripheral blood OB test, fractionation in the gravity field.

2020 ◽  
Vol 69 (2) ◽  
pp. 15-34
Author(s):  
Andrzej Górka

The publication describes a simplified model of the process of fractionation of binary biological mixtures in a closed reference system. The description of the model uses a balance of masses and forces forcing microparticle movement in a base fluid matrix. The movement, consistent with the direction of the excitation forces, was limited to independent migration channels with diameters comparable to the diameters of the migrating microparticles. In this model, the parameters of the densification process of the separated fraction in a single migration channel were applied to the entire volume of the fractioned mixture. The developed model applies to theoretical bases of the erythrocyte sedimentation rate (ESR). Keywords: biological mixture fractionation, blood component sedimentation, mixture fractionation process model, peripheral blood ESR testing, fractionation in gravity field, fractionation in a centrifugal-force field


2010 ◽  
Vol 61 (4) ◽  
pp. 273-289 ◽  
Author(s):  
Margaret Stroebe ◽  
Henk Schut

The Dual Process Model of Coping with Bereavement (DPM; Stroebe & Schut, 1999) is described in this article. The rationale is given as to why this model was deemed necessary and how it was designed to overcome limitations of earlier models of adaptive coping with loss. Although building on earlier theoretical formulations, it contrasts with other models along a number of dimensions which are outlined. In addition to describing the basic parameters of the DPM, theoretical and empirical developments that have taken place since the original publication of the model are summarized. Guidelines for future research are given focusing on principles that should be followed to put the model to stringent empirical test.


1997 ◽  
Vol 19 (3) ◽  
pp. 283-287 ◽  
Author(s):  
Y Katayama ◽  
T Yano ◽  
A Bessho ◽  
S Deguchi ◽  
K Sunami ◽  
...  

2019 ◽  
Vol 68 (3) ◽  
pp. 15-34
Author(s):  
Andrzej Górka

The paper presents a simplified method of estimating the amount and specific mass of microparticles in complex biological mixtures using the fractionation process in the field of centrifugal forces. In the presented method, using the heaviest blood cells – erythrocytes – as an example, a geometric model of a binary fraction in a borderline equilibrium state formed in the process of blood fractionation was used. In this model, an approximated shape of the erythrocyte and a sample normal distribution of the size and number of microparticles in the examined model fraction filled with erythrocytes were used. Based on publicly available blood data, it has been shown that it is possible to estimate the amount and specific weight of microparticles. The accuracy of such estimation generally depends on the precision of representation of shapes, the degree of filling the fraction with microparticles and on the individual quantitative and dimensional distribution of these particles in the examined fraction. The above conclusions, which determine the accuracy of the method presented, were verified in the paper with the use of rheological blood data, commonly available in literature for various types of measuring containers, which affect the level of filling of a given fraction with microparticles. Keywords: fractionation of biological mixtures, fractionation of blood components, erythrocyte model, erythrocyte shape, blood components


1965 ◽  
Vol 52 (6) ◽  
pp. 137-138 ◽  
Author(s):  
K. C. Das ◽  
S. Abdullah ◽  
Shilla Rohatgi ◽  
J. Chatterjee

2009 ◽  
Vol 24 (20) ◽  
pp. 1605-1615 ◽  
Author(s):  
XIAOXIONG ZENG

The fermions tunneling formulism of Kerner and Mann is extended to the case of black holes with electric and magnetic charges. As the electric and magnetic fields would couple with gravity field, we introduce the Dirac equation of charged and magnetized particles. We study the spin-up particles from the Reissner–Nordström black hole with magnetic charges and spin-down particles from the Kerr–Newman–Kasuya black hole and obtain the corresponding emission temperatures. In particular, we also provide a simplified method by defining an equivalent charge and gauge potential to further discuss tunneling of charged and magnetized fermions, which reproduces the same results as obtained above.


2019 ◽  
Vol 9 (9) ◽  
pp. 606
Author(s):  
Daiki Suehiro ◽  
Ken Fukami ◽  
Tsuyoshi Takara

Background: Osteoporosis is characterized by reduced bone mineral density (BMD) and increased fracture risk, with a higher incidence in post-menopausal women. This study aimed to evaluate the safety and efficacy of long-term ingestion of corn syrup solids containing maltobionic acid on BMD in healthy Japanese women.Methods: A randomized, double-blind, placebo-controlled, parallel-group study was conducted from February to December 2018. Thirty-eight healthy Japanese women aged 50–69 years who were at least 1 year past the onset of natural menopause were allocated to two groups (19 in each group) using a computerized random-number generator: one in which participants ingested 7 g of corn syrup containing maltobionic acid and another in which participants ingested 7 g of placebo (maltose syrup) group per day for 24 weeks. BMD and bone metabolism parameters were measured by DEXA (dual-energy X-ray absorptiometry method) and a peripheral blood test, respectively, while safety was evaluated via a physical examination, peripheral blood test, urinalysis, assessment of subjective symptoms, and a medical questionnaire.Results: Thirty-three subjects completed the study, except for one subject who discontinued the study halfway, and there were no adverse events related to consumption of the test food. Fourteen subjects were excluded before the efficacy analysis because of conflict with control criteria; the remaining 23 subjects were studied (10 in the Test food group and 13 in the Placebo group). Consumption of corn syrup solids containing maltobionic acid was maintained during the intervention period, and BMD, bone mineral content (BMC), and YAM (young adult mean) values were found to be improved (P < 0.05). No safety concerns were observed during the intervention period.Conclusion: These results indicate that the consumption of corn syrup solids containing maltobionic acid may contribute to the prevention of osteoporosis.


2019 ◽  
Vol Volume 12 ◽  
pp. 11413-11423 ◽  
Author(s):  
Yiyang Wu ◽  
Zimu Song ◽  
Kuisheng Sun ◽  
Shikuo Rong ◽  
Peng Gao ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document