Theta Rhythmopathy as a Cause of Cognitive Disability in TLE
Keyword(s):
Memory difficulties are commonly associated with temporal lobe epilepsy (TLE) and cause significant disability. This article reviews the role of altered hippocampal theta oscillations and theta-gamma coupling as potential causes of memory disturbance in temporal lobe epilepsy, dissecting the potential mechanisms underlying these changes in large-scale neuronal synchronization. We discuss development of treatments for cognitive dysfunction directed at restoring theta rhythmicity and future directions for research.
2014 ◽
Vol 34
(4)
◽
pp. 1105-1114
◽
Keyword(s):
1992 ◽
Vol 12
(5)
◽
pp. 1867-1881
◽
Keyword(s):
2009 ◽
Vol 6
(4)
◽
pp. 6441-6489
◽
Keyword(s):
2018 ◽
Vol 86
(9)
◽
pp. 2501-2505
Keyword(s):