scholarly journals Cytological finding of cutaneous angiosarcoma occuring 15 years after the treatment of double carcinomas (gastric adenocarcinoma and uterine cervical squamous cell carcinoma)

2005 ◽  
Vol 44 (1) ◽  
pp. 34-35
Author(s):  
Takazo OKUYAMA ◽  
Yasunori ENOMOTO ◽  
Kunio ICHIJIMA ◽  
Tsuneo NODA ◽  
Akitaka NONOMURA
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Gastric Adenocarcinoma ◽  
Squamous Cell ◽  
Cervical Squamous Cell Carcinoma ◽  
Cytological Finding

Immunohistochemical staining of podoplanin is helpful in determining the microinvasion of cervical squamous cell carcinoma

2020 ◽  
Vol 46 ◽  
pp. 151493
Author(s):  
Xiaowen Qiao ◽  
Yuhong Sun ◽  
Ying Zou ◽  
Jiaxiang Lin ◽  
Wei Xu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Immunohistochemical Staining ◽  
Cervical Squamous Cell Carcinoma

scholarly journals Significance of miR-141 and miR-340 in cervical squamous cell carcinoma

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 864-872
Author(s):  
Wenting Li ◽  
Bo Yang ◽  
Yiqun Li ◽  
Cuicui Wang ◽  
Xinzhi Fang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Target Gene ◽  
Squamous Epithelium ◽  
Figo Stage ◽  
Cervical Squamous Cell Carcinoma ◽  
Squamous Intraepithelial Lesion ◽  
Nerve Invasion ◽  
Intraepithelial Lesion

Abstract Background We investigated the expression and clinical significance of miR-141 and miR-340 in cervical squamous cell carcinoma (CSCC). Methods Expression of miR-141 and miR-340 in CSCC, high-grade squamous intraepithelial lesion (HSIL), and normal cervical squamous epithelium were detected by qRT-PCR. PTEN was assessed by immunohistochemistry. Their relationship with clinicopathological features was analyzed. Results The changes of miR-141 and miR-340 were different in CSCC, HSIL, and normal squamous epithelium (P = 0.030). miR-141 expression was statistically significant in gross type, differentiation, uterine corpus invasion, nerve invasion, vagina invasion, and FIGO stage in CSCC (P < 0.05). miR-340 expression was related to tumor size, differentiation, nerve invasion, lymph node metastasis, and FIGO stage in CSCC (P < 0.05). miR-141 and miR-340 expressions were statistically significant in different ages (P < 0.05) in HSIL. The AUC of miR-141 in CSCC diagnosis and that of miR-340 in HSIL diagnosis were 0.893 and 0.764, respectively. The sensitivity and the specificity of miR-141 for diagnosis of CSCC were 95.0% and 60.8%, respectively, while those of miR-340 for diagnosis of HSIL were 90.0 and 48.6%, respectively. miR-141 and miR-340 expressions are associated with PTEN expression (P = 0.002 and P < 0.001). Conclusion miR-141 and miR-340 may be associated with their target gene PTEN and involved in the carcinogenesis of cervical squamous epithelium.

Pathologic Determination of Multifocality in pT1a1 Squamous Cell Carcinoma of the Cervix: A Retrospective Analysis

2021 ◽  
pp. 106689692199072
Author(s):  
Jingjing Hu ◽  
Kojo R. Rawish ◽  
Mariah Leivo ◽  
Dennis Adams ◽  
Somaye Y. Zare ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Residual Disease ◽  
Cervical Squamous Cell Carcinoma ◽  
Tnm Staging ◽  
Stromal Invasion ◽  
Lateral Extent ◽  
Clinicopathologic Parameters

When more than one focus of stromal invasion is present in a superficially invasive cervical squamous cell carcinoma (SCC), determination of the tumoral lateral extent/horizontal extension, and hence tumor-nodes-metastases (TNM) staging, can be problematic. In recent years, a diagnostic approach to distinguish multifocal pT1a1 from pT1b cases has gained increased attention. These criteria call for classifying SCC as multifocal when invasive foci are separated by blocks of uninvolved cervical tissues, and/or are located on separated cervical lips in a tumor that is discontinuous, and/or are situated far apart (≥2 mm) from each other. In this study, we assess our experience with multifocal stage pT1a1 cervical SCC that was retrospectively classified as such using these criteria. Slides from the loop electrosurgical excision or conization specimens, comprising 212 pT1a1, 173 pT1a2, and 206 pT1b cases, were reviewed. Twenty-four (11%) of the 212 pT1a1 cases were classified as multifocal after review. The 24 multifocal pT1a1 cases were compared with the 188 unifocal pT1a1 cases regarding a variety of clinicopathologic parameters. Notably, these 2 groups showed no significant differences regarding all parameters that were evaluated, including patient age, recurrence rate, primary tumoral features in the primary excision specimen (rate of positive margins, median depth of stromal invasion, frequency of lymphovascular invasion), and frequency of residual disease in additional excisions. In summary, we demonstrate comparably favorable patient outcomes in both unifocal and multifocal cases of pT1a1 SCC of the cervix, and, accordingly, we conclusively affirm the validity of the aforementioned criteria for establishing multifocality.

NUCKS1 overexpression is a novel biomarker for recurrence-free survival in cervical squamous cell carcinoma

Tumor Biology ◽  
2014 ◽  
Vol 35 (8) ◽  
pp. 7831-7836 ◽  
Author(s):  
Lina Gu ◽  
Bairong Xia ◽  
Lili Zhong ◽  
Yuan Ma ◽  
Lei Liu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Squamous Cell Carcinoma ◽  
Recurrence Free Survival ◽  
Free Survival

Recurrence during pregnancy of a conservatively treated early-stage cervical squamous cell carcinoma

2011 ◽  
Vol 95 (1) ◽  
pp. 290.e13-290.e16 ◽  
Author(s):  
Pascale Jadoul ◽  
Denis Querleu ◽  
Jean-Luc Squifflet ◽  
Jacques Donnez
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Cervical Squamous Cell Carcinoma

Increased expression of apoptosis-related protein 3 is highly associated with tumorigenesis and progression of cervical squamous cell carcinoma

2013 ◽  
Vol 44 (3) ◽  
pp. 388-393 ◽  
Author(s):  
Yaqing Zhang ◽  
Qinlong Li ◽  
Weiqing Huang ◽  
Jing Zhang ◽  
Zenglei Han ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Squamous Cell Carcinoma ◽  
Related Protein ◽  
Tumorigenesis And Progression ◽  
Apoptosis Related Protein
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