scholarly journals Liver Abscess Caused by Fusobacterium nucleatum: A Case Report

2021 ◽  
Vol 14 (4) ◽  
Author(s):  
Wenhao Wu ◽  
Wenjia Fan ◽  
Zhewen Zhou ◽  
Shouhao Wang ◽  
Chengan Xu ◽  
...  
Keyword(s):  
Liver Abscess ◽  
Pathogenic Bacteria ◽  
Anaerobic Bacteria ◽  
Fusobacterium Nucleatum ◽  
Pyogenic Liver Abscess ◽  
Microbial Detection ◽  
Specimen Collection ◽  
First Case ◽  
Positive Rate ◽  
Bacteria Culture

Introduction: Pyogenic liver abscess (PLA) is a serious infectious disease of the liver. PLA caused by Fusobacterium nucleatum is extremely rare. Here we report the first case of liver abscess caused by F. nucleatum in China. Case Presentation: The case was a 34-year-old female patient admitted to the hospital due to high fever. The diagnosis of liver abscess was confirmed by imaging studies and liver puncture. We finally confirmed the pathogen as F. nucleatum by next-generation sequencing (NGS). After the targeted anti-infective treatment, the patient recovered and discharged. Conclusions: As a new microbial detection method, NGS can still help in clinical practice. In addition, to improve the positive rate of anaerobic bacteria culture, we should pay attention to avoid contact with air in the process of specimen collection when the pathogenic bacteria are suspected to be anaerobic bacteria.

Fusobacterium nucleatum detected simultaneously in a pyogenic liver abscess and advanced sigmoid colon cancer

Anaerobe ◽  
2017 ◽  
Vol 48 ◽  
pp. 144-146 ◽  
Author(s):  
Ryuta Shigefuku ◽  
Tsunamasa Watanabe ◽  
Yuki Kanno ◽  
Hiroki Ikeda ◽  
Hiroyasu Nakano ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Sigmoid Colon ◽  
Liver Abscess ◽  
Fusobacterium Nucleatum ◽  
Pyogenic Liver Abscess ◽  
Sigmoid Colon Cancer

scholarly journals A Case of Liver Abscess withDesulfovibrio desulfuricansBacteremia

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Saho Koyano ◽  
Keita Tatsuno ◽  
Mitsuhiro Okazaki ◽  
Kiyofumi Ohkusu ◽  
Takashi Sasaki ◽  
...  
Keyword(s):  
Liver Abscess ◽  
Clinical Presentation ◽  
Anaerobic Bacteria ◽  
Desulfovibrio Desulfuricans ◽  
Clinical Specimens ◽  
Sulfate Reducing ◽  
Oral Amoxicillin ◽  
First Case ◽  
Causative Agents ◽  
Amoxicillin Clavulanic Acid

Desulfovibriospp. are gram-negative, sulfate-reducing, and anaerobic bacteria found in the digestive tract of humans. BecauseDesulfovibriospp. are infrequent causative agents of infectious diseases and are difficult to isolate and to identify from clinical specimens, the appropriate antibiotic therapy to infection withDesulfovibriospp. has not been determined. We report the first case of liver abscess with bacteremia due toDesulfovibrio desulfuricansto show the clinical presentation and treatment. The patient was successfully treated with intravenous piperacillin-tazobactam and oral amoxicillin-clavulanic acid.

scholarly journals Fusobacterium Nucleatum : An Atypical Cause of Pyogenic Liver Abscess in an Apparently Immunocompetent Patient

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Yusoff AR ◽  
Abd Razak NA ◽  
Samsuddin S ◽  
Mokhtar S
Keyword(s):  
Liver Abscess ◽  
Percutaneous Drainage ◽  
Fusobacterium Nucleatum ◽  
Pyogenic Liver Abscess ◽  
Enteric Bacteria ◽  
Operative Management ◽  
Immunocompetent Patient ◽  
Immunocompromised Status ◽  
Anaerobic Infections ◽  
Non Operative Management

Pyogenic liver abscess is an uncommon but potentially lethal infection if left untreated. Enteric bacteria and anaerobes are the most common causative organisms of pyogenic liver abscess. Although most infections are of a polymicrobial nature, monomicrobial infections are possible. An immunocompromised status and the presence of periodontal disease are the risk factors for liver abscess caused by these rare, monomicrobial anaerobic infections. Here, we report on a successful non-operative management of a case of multiloculated pyogenic liver abscess caused by Fusobacterium nucleatum in a young, healthy, immunocompetent male patient. The diagnosis was established by radiological imaging and was based on a positive aspirate culture, whereas the mainstay of treatment comprised percutaneous drainage and a prolonged course of antibiotics. Thus, the patient was successfully treated with a 2-week course of intravenous imipenem/cilastatin while he was on percutaneous drainage, and he is now doing well.

scholarly journals Pyogenic Liver Abscess, Bacteremia, and Meningitis with HypermucoviscousKlebsiella pneumoniae: An Unusual Case Report in a Human T-Cell Lymphotropic Virus Positive Patient of Caribbean Origin in the United States

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Gargi Patel ◽  
Neha Shah ◽  
Roopali Sharma
Keyword(s):  
Liver Abscess ◽  
Unusual Case ◽  
Pyogenic Liver Abscess ◽  
The United States ◽  
Causative Organism ◽  
Unique Form ◽  
E Coli ◽  
First Case ◽  
Human T Cell ◽  
Unusual Case Report

Pyogenic liver abscess (PLA) is a potentially fatal disease.Klebsiella pneumoniae(K. pneumoniae) has replacedEscherichia coli(E. coli) as the predominant causative organism for pyogenic liver abscess. Over the years a unique form of community-acquired invasiveK. pneumoniaeinfection of the liver has been well described in Southeast Asia. This has recently been linked to a virulent hypermucoviscousK. pneumoniaephenotype and to a specific genotype,rmpApositive. To our knowledge, we report the first case of PLA with bacteremia and meningitis in a Guyanese patient with the presence ofrmpA-positiveK. pneumoniaewith laboratory evidence in North America.

scholarly journals Case of Pyogenic Liver Abscesses Caused by Klebsiella Pneumoniae

2018 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Liver Abscess ◽  
Anaerobic Bacteria ◽  
Pyogenic Liver Abscess ◽  
Hepatobiliary Disease ◽  
Liver Abscesses ◽  
Patients With Diabetes ◽  
Aerobic And Anaerobic

Liver abscess is a serious intraabdominal infection can be due to result of bacteria, fungi, or parasites infection. Until the end of the last century, pyogenic liver abscesses were predominantly caused by mixed aerobic and anaerobic bacteria, the most frequent isolate being Escherichia coli [1]. Klebsiella pneumoniae (K.pneumoniae) is a known cause of pyogenic liver abscess (PLA) in the absence of hepatobiliary disease. In settings of hepatic infection, it has also been known to cause disseminated infections including meningitis and endopthalmitis. Patients with diabetes mellitus and the preexisting hepatobiliary disease are particularly susceptible to infection as well as those from Southeast Asia [2]. We present a case of Klebsiella liver abscess with bacteremia.

scholarly journals Clinical Significance of Serum Albumin/Globulin Ratio in Patients With Pyogenic Liver Abscess

2021 ◽  
Vol 8 ◽  
Author(s):  
Jia Zhang ◽  
Tao Wang ◽  
Yi Fang ◽  
Mengzhou Wang ◽  
Wuming Liu ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Clinical Significance ◽  
Liver Abscess ◽  
Clinical Manifestations ◽  
Pyogenic Liver Abscess ◽  
Peritoneal Effusion ◽  
Positive Rate ◽  
Treatment Plans ◽  
The Mean ◽  
Clinical Characteristic

Pyogenic liver abscess (PLA) remains a significant challenge for modern clinicians. Serum albumin/globulin ratio (AGR) can reflect the progress of many diseases. However, the clinical significance of AGR in PLA has not been evaluated. The aim of this study was to explore the effect of AGR on the clinical characteristic and prognosis in PLA patients. This retrospective study included 392 PLA patients who admitted to the First Affiliated Hospital of Xi'an Jiaotong University from January, 2007 to December, 2016. The medical records on admission were collected. Compared with the healthy controls and the patients with extraperitoneal infection or non-infectious liver disease, PLA patients had lower levels of AGR. The mean level of AGR in PLA patients was 1.02 ± 0.25. There were 179 (45.4%) patients with AGR > 1.02 and 213 (54.6%) patients with AGR ≤ 1.02. The baseline data and treatment plans of PLA patients with high or low AGR were comparative. However, PLA patients with a low AGR had higher body temperature, leukocytes and neutrophils, lower hemoglobin, poorer liver and coagulation function, larger abscess diameter, higher positive rate of pus culture and proportion of Escherichia coli, and were more susceptible to multiple bacteria. Moreover, PLA patients with a low AGR had more complications, including systemic inflammatory response syndrome (SIRS), peritoneal effusion and pleural effusion. And it also needs longer time for temperature normalization and hospital stay. In conclusion, PLA patients have lower AGR and lower AGR is associated with worse clinical manifestations, more complications and poorer prognosis. Thus, monitoring of AGR is of great clinical significance for evaluating the progress of PLA patients.

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