Intraocular Medulloepithelioma

2012 ◽  
Vol 136 (2) ◽  
pp. 212-216 ◽  
Author(s):  
Timothy Saunders ◽  
Curtis E. Margo
Keyword(s):  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Good Prognosis ◽  
Definitive Diagnosis ◽  
Ciliary Epithelium ◽  
Histologic Diagnosis ◽  
Fine Needle ◽  
Congenital Tumor ◽  
Mesenchymal Tissue ◽  
The Central Nervous System

Intraocular medulloepithelioma is a congenital tumor of the ciliary epithelium that typically presents during the first decade of life. The histologic diagnosis is based on characteristic ribbons of pseudostratified neuroepithelium admixed with loose mesenchymal tissue rich in hyaluronic acid, vaguely resembling developing retina and vitreous. More than a third of medulloepitheliomas contain heteroplastic tissue, which in some cases makes up most of the tumor. Malignant medulloepitheliomas consist of a proliferation of neuroblasts, which in areas can be indistinguishable from retinoblastoma. Unlike its highly malignant counterpart in the central nervous system, intraocular medulloepithelioma has a good prognosis as long as tumor has not spread beyond the eye. Definitive diagnosis and eye-conserving therapy is possible with fine-needle aspiration biopsy. The histologic differential diagnosis of medulloepithelioma is broad, ranging from retinoblastoma and sarcoma to ciliary epithelial adenoma and adenocarcinoma.

Diagnosis of Lymphoma Using Fine-Needle Aspiration Biopsy and Core-Needle Biopsy: A Single-Institution Experience

2019 ◽  
Vol 63 (3) ◽  
pp. 198-205
Author(s):  
Fatima-Zahra Jelloul ◽  
Maria Navarro ◽  
Pooja Navale ◽  
Tamla Hagan ◽  
Rubina S. Cocker ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
Single Institution ◽  
Core Needle ◽  
Fine Needle ◽  
Ancillary Studies

Objective: The objective is to study the efficacy of fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB) in the diagnosis of lymphoma in a single institution. Study Design: We retrospectively reviewed 635 FNAB/CNB cases performed in our institution to rule out lymphoma during a 4-year period and collected the relevant clinical and pathological information for statistical analysis. Results and Conclusions: This cohort comprised 275 males and 360 females, with a median age of 57 years. Among the 593 cases with adequate diagnostic materials for lymphoma work-up, 226 were positive for lymphoma, 286 were negative for lymphoma, and 81 were nondiagnostic. Each case had an FNAB, and 191 cases also underwent a CNB. The subclassification rate according to the WHO (2008) was 67% overall, 81% for the FNAB with CNB group, and 40% for the FNAB group. In the FNAB with CNB group, the subclassification rates for cases with and without a history of lymphoma were not significantly different. A definitive diagnosis of lymphoma relied on ancillary studies, but was not affected by location, or the needle gauge of CNB. Follow-up data revealed a high diagnostic accuracy of FNAB with CNB. In conclusion, the use of FNAB and CNB with ancillary studies is effective in providing a definitive diagnosis of lymphoma in our experience at the Northwell Health System.

Histopathology and Cytopathology of Neuroendocrine Tumors and Carcinomas of the Breast: A Review

2019 ◽  
Vol 63 (4) ◽  
pp. 340-346 ◽  
Author(s):  
Robert Y. Osamura ◽  
Naruaki Matsui ◽  
Misa Okubo ◽  
Lan Chen ◽  
Andrew S. Field
Keyword(s):  
Neuroendocrine Tumors ◽  
Who Classification ◽  
Fine Needle Aspiration Biopsy ◽  
Recent Literature ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
High Grade ◽  
Fine Needle ◽  
International Academy ◽  
Specific Management

Neuroendocrine tumors (NET) and carcinomas (NEC) of the breast are rare diseases, but NEC has attracted attention in both cytopathology and surgical pathology because of its specific management and prognosis. Fine-needle aspiration biopsy (FNAB) cytology can make the diagnosis in many cases particularly with high-grade NEC, with definitive diagnosis based on histopathology and immunohistochemistry. This review describes the characteristics of the disease based on the WHO classification 2012 and recent literature and ­includes discussion related to the International Academy of Cytology Yokohama System of Reporting Breast FNAB ­cytology.

The diagnostic value of ultrasound-guided fine-needle aspiration biopsy in breast masses

1993 ◽  
Vol 29 (3) ◽  
pp. 535
Author(s):  
Nam Hee Lee ◽  
Hyun Yang Lim ◽  
Noh Kyoung Park ◽  
Seok Tae ◽  
Kyung Ja Shin ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Diagnostic Value ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Ultrasound Guided ◽  
Breast Masses ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

LYMPHOID INFILTRATION IN TOXIC GOITRES STUDIED WITH FINE NEEDLE ASPIRATION BIOPSY

1972 ◽  
Vol 71 (3) ◽  
pp. 480-490 ◽  
Author(s):  
Göran Nilsson
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Lymphoid Cells ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Needle Aspiration Biopsy ◽  
Lymphoid Infiltration ◽  
Long Acting

ABSTRACT Cytodiagnostic fine needle aspiration biopsy specimens from toxic goitres were studied for signs of lymphoid infiltration. Comparison with histological sections of specimens obtained by surgery showed that an excess of lymphoid cells in the aspirate smears corresponded to a large number of lymphoid foci in these sections. Excess of lymphoid cells in the fine needle aspirates was also positively correlated with the occurrence of circulating thyroid antibodies against thyroglobulin and/or cytoplasmic antigen, but not with the presence of the long-acting thyroid stimulating factor, LATS. It also varied with age in that it was most common in the youngest patients and in patients between 40–55 years, while lymphoid infiltration was seldom seen in patients over 55 years. A finding of practical clinical interest was that in toxic goitres with cytological signs of lymphoid infiltration hyperthyroidism had less tendency to recur after treatment with thiocarbamide drugs than in those without such signs.

Sign in / Sign up

Export Citation Format

Share Document