scholarly journals Differential Staged Sacral Reflexes: Methodology and Normal Values from 51 Healthy Subjects and 134 Patients with Pudendal Neuralgia

2012 ◽  
Vol 2 (4) ◽  
pp. 21-26
Author(s):  
Eric de Bisschop ◽  
Rajeshree Nundlall
Author(s):  
Elif Gündoğdu ◽  
Uğur Toprak

Background: The middle ear cavity is ventilated through the aditus ad antrum. Aditus blockage contributes to the pathology of otitis media. Objective: To determine the normal values of the aditus ad antrum diameter on computed tomography and to investigate its relationship with chronic otitis media and related pathologies (tympanosclerosis and myringosclerosis). Methods: The temporal CT images of 162 individuals were evaluated retrospectively. In the axial sections, the inner diameter of the aditus was measured at the narrowest point at the cortex. The differences in diameter were compared between diseased and healthy ears. Results: In healthy individuals, the diameter was narrower in women. There was no difference between the right and left ears in healthy subjects. No correlation was found between age and diameter. In male patients with myringosclerosis, the diameter was slightly narrower on both sides but more marked on the left. In female patients with myringosclerosis, the diameter in both ears was slightly narrower. In cases of otitis media and tympanosclerosis, the diameter was less than that of healthy individuals, despite the lack of statistically significant result in all cases. Conclusion: The aditus ad antrum was narrower in diseased ears, indicating that a blocked aditus may contribute to the development of otitis media, as well as mucosal diseases.


2005 ◽  
Vol 40 (7) ◽  
pp. 768-774 ◽  
Author(s):  
Jörgen Wenner ◽  
Folke Johnsson ◽  
Jan Johansson ◽  
Stefan Öberg

During several expeditions to the Jungfraujoch (3450 m) the effect of residence at altitude upon various nervous functions of healthy subjects was studied. The threshold of cutaneous and gustatory sensitivity, the threshold of the knee-jerk reflex, the amplitude of equilibratory movements and the reaction time to optic stimulation were measured at 560 or 800 m, and on the same subjects during a stay of 2 or 3 weeks on the Jungfraujoch, and finally once more after the return to the plain. Apparatus was specially adapted for this (Fleisch 1945; Grandjean 1948a).The major results were as follows: the thresholds of cutaneous sensitivity were lowered at an altitude of 3450 m in forty-two of fifty examined subjects. The thresholds returned to normal values in some subjects at the end of the stay at Jungfraujoch and in all subjects after the return to the plain. An analogous result was obtained by either measuring the cutaneous sensitivity electrically or by measuring the sensitivity of the cornea with a hair (Grandjean 19486). The thresholds of gustatory sensitivity to glucose, NaCl, tartaric acid and to quinine were lowered in all 18 subjects examined during their stay at the Jungfraujoch (Fleisch & Grandjean J944).


1996 ◽  
Vol 21 (4) ◽  
pp. 350
Author(s):  
B. Erbas ◽  
N. Kahraman ◽  
Y. Li ◽  
C. D. Russell ◽  
E. V. Dubovsky

1993 ◽  
Vol 39 (6) ◽  
pp. 980-985 ◽  
Author(s):  
M A Mansoor ◽  
A B Guttormsen ◽  
T Fiskerstrand ◽  
H Refsum ◽  
P M Ueland ◽  
...  

Abstract We administered reduced L-homocysteine perorally (67 mumol/kg of body wt) to 12 healthy subjects and injected the same dose into one person, and determined the kinetics of the alterations in reduced, oxidized, and protein-bound concentrations of homocysteine, cysteine, and cysteinylglycine. After oral intake, reduced homocysteine increased rapidly (tmax < or = 15 min), reaching concentrations [3.97 (SD 2.99) mumol/L] 20-fold above fasting values, and then declined towards the normal concentration within 2 h. There was a similar increase in reduced cysteine and a moderate increase in reduced cysteinylglycine. During this response, we observed a positive correlation between the reduced/total ratio for homocysteine and cysteine. When homocysteine was injected, the increase in reduced homocysteine preceded the increase in reduced cysteine by about 3 min. After oral loading, oxidized homocysteine showed a transient increase (tmax = 30 min) that lagged behind the increase of reduced homocysteine. Oxidized cysteine and cysteinylglycine were stable or decreased slightly. Protein-bound homocysteine increased the least rapidly after homocysteine administration (tmax = 1-2 h), and returned to normal values slowly. Changes in protein-bound homocysteine essentially mirrored a concurrent decrease in protein-bound cysteine, suggesting displacement of bound cysteine. These data show that plasma homocysteine has a pronounced, direct effect on the redox status and protein binding of other plasma thiol components. Such effects should be recognized when studying the mechanisms behind the atherogenic effect of increased plasma homocysteine.


2000 ◽  
Vol 5 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Yuji Nakazato ◽  
Yasuro Nakata ◽  
Kaoru Nakazato ◽  
Masayuki Yasuda ◽  
Masataka Sumiyoshi ◽  
...  

1988 ◽  
Vol 64 (5) ◽  
pp. 2215-2219 ◽  
Author(s):  
I. Rubinstein ◽  
A. S. Slutsky ◽  
A. S. Rebuck ◽  
P. A. McClean ◽  
R. Boucher ◽  
...  

Maximal static expiratory pressure developed at the mouth (PEmax) provides a useful clinical index of expiratory muscle function; however, the range of normal values among laboratories shows considerable variation. We examined the hypothesis that the wide variability could be attributable to the differences in technique among laboratories. We measured PEmax at functional residual capacity (PEmax FRC) in 28 healthy subjects using the following five techniques: 1) using a scuba-type mouthpiece with the cheeks supported by the hands ("hands on"), 2) without supporting the cheeks ("no hands"), 3) using a rigid, circular mouthpiece (2.8 cm ID, "tube"), 4) using the scuba-type mouthpiece but with the cheeks supported by an observer ("other hands"), and 5) using a large-bore circular mouthpiece (4.1 cm ID, "new tube"). Mean PEmax FRC obtained with hands on was significantly higher than no-hands and tube methods. PEmax FRC values obtained by the other-hands and new-tube maneuvers were similar to the hands-on maneuver. We conclude that the technique used to measure PEmax FRC can significantly affect the results and suggest that it should be measured using a large-bore circular mouthpiece or a scuba-diving mouthpiece with the cheeks supported.


1996 ◽  
Vol 16 (6) ◽  
pp. 762-768 ◽  
Author(s):  
Kazuo Moroe ◽  
Tadayuki Hiroki ◽  
Toru Iwa ◽  
Tadashi Kobayashi ◽  
Yuji Nakazato ◽  
...  

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