scholarly journals Relationship between actinic keratosis and malignant skin lesions on the eyelid

2022 ◽  
Vol 86 (1) ◽  
Author(s):  
Luiz Angelo Rossato ◽  
Rachel Camargo Carneiro ◽  
Erick Marcet Santiago de Macedo ◽  
Patricia Picciarelli de Lima ◽  
Mariana Ragassi Urbano ◽  
...  
Keyword(s):  
Actinic Keratosis ◽  
Skin Lesions ◽  
Malignant Skin

scholarly journals Dermatoses in parkinsonism: the importance of multidisciplinary follow-up

2019 ◽  
Vol 65 (6) ◽  
pp. 791-795 ◽  
Author(s):  
Isadora Antunes ◽  
Kátia Sheylla Malta Purim ◽  
Luara Leticia Grande ◽  
Nathália Cristina Alberton ◽  
Tatiana Francinne Regis Navarro ◽  
...  
Keyword(s):  
Actinic Keratosis ◽  
Seborrheic Dermatitis ◽  
Skin Lesions ◽  
Disease Diagnosis ◽  
Seborrheic Keratosis ◽  
Cross Sectional ◽  
Inflammatory Dermatoses ◽  
Malignant Skin ◽  
Pigmented Nevus

Summary Parkinsonism is characterized by bradykinesia with rigidity and/or resting tremor, in addition to non-motor symptoms, which include dermatological manifestations. The objective of this study is to evaluate the main dermatoses in patients with parkinsonism found at the Philanthropic Association of Curitiba - PR. A cross-sectional descriptive study was carried out with the application of a questionnaire and dermatological evaluation of the patients. The sample consisted of 386 patients and was composed mainly by men (55.4%), between 60-74 years old (51.6%), with complete primary education (45.3%), disease diagnosis time between 5-10 years (35%) and in use of medication (96.6%). The most prevalent dermatoses were pigmented nevus (36.3%), warts (25.1%), actinic keratosis (22%), seborrheic keratosis (21.5%), seborrheic dermatitis (20.5%), and rosacea (19.2%). Among the 13 cases (3.4%) of malignant cutaneous neoplasms confirmed by biopsy, 2 were melanomas. Regarding patients’ sex, there was a higher prevalence of inflammatory dermatoses (OR 1.64, 95% CI 1.08-2.51, p = 0.025) and benign cutaneous neoplasms (OR 1.77, 95% CI 1.16-2.69, p = 0.01) in men. As to age, patients aged between 60-74 years had more pre-malignant skin lesions (OR 2.60, 95% CI 1.05-6.44, p <0.001) and seborrheic keratosis (OR 2.52, 95% CI 1.02-6.25, p = 0.001) and, in those older than 75 years, actinic keratosis was more frequent (OR 5.43, 95% CI 2.17-13.6, p <0.001). The results of the study show that it is fundamental to dermatologically evaluate and monitor these patients, aiming at diagnosis and early treatment of lesions, especially of skin cancer.

scholarly journals Off-Label 9-Valent Human Papillomavirus Vaccination for Actinic Keratosis: A Case Series

2021 ◽  
pp. 457-463
Author(s):  
Emily Wenande ◽  
Niels Bech-Thomsen ◽  
Katrine Togsverd-Bo ◽  
Merete Haedersdal
Keyword(s):  
Human Papillomavirus ◽  
Actinic Keratosis ◽  
Hpv Vaccination ◽  
Case Series ◽  
Skin Lesions ◽  
Human Papillomavirus Vaccination ◽  
Off Label ◽  
Dermatology Clinic ◽  
Regular Control ◽  
Malignant Skin

<b><i>Background:</i></b> The suspected link between human papillomavirus (HPV) and the development of premalignant and malignant skin lesions remains inadequately examined in clinical settings. This case series describes HPV vaccination as an off-label adjuvant therapy for actinic keratosis (AK). <b><i>Methods:</i></b> Twelve immunocompetent AK patients underwent HPV vaccination at a private dermatology clinic in Naestved, Denmark. Prior to vaccination, all patients demonstrated a high AK burden that required regular control visits. At 0, 2, and 6 months, the patients received an intramuscular injection of a commercially available 9-valent HPV vaccine. Concurrently, patients continued conventional AK therapies at 3-month intervals. Clinical response, consisting of reduction in AK number and general change in skin appearance, was assessed by a dermatologist over 12 months following first vaccination. <b><i>Results:</i></b> All patients (mean age 76.2 years; 10 M and 2 F) completed the vaccine schedule. Overall, an average 85% reduction in total AK burden was recorded 12 months after beginning vaccination. Median AK burden thus fell from 56 (IQR: 44–80) to 13.5 (IQR: 1–18) lesions after 12 months. Lesion reduction was observable by the second inoculation at month 2 (34 AKs; IQR 22–80), continuing steadily until month 6 (15 AKs; IQR 5–30) and plateauing between 6 and 12 months. Clinically, HPV vaccination elicited fading of lesions’ erythematous background after the first dose, often followed by sloughing of hyperkeratotic elements in subsequent weeks. Patients reported no adverse effects related to HPV vaccination. <b><i>Conclusion:</i></b> This case series introduces the possibility that 9-valent HPV vaccination in combination with conventional treatments may be used as a therapeutic strategy for AK.

Special Considerations In The Management Of Malignant Skin Lesions About The Eye

1993 ◽  
Vol 26 (2) ◽  
pp. 215-230
Author(s):  
Gerry F. Funk ◽  
Henry T. Hoffman ◽  
Keith D. Carter
Keyword(s):  
Skin Lesions ◽  
Malignant Skin

Pre-malignant skin lesions

Medicine ◽  
2021 ◽  
Author(s):  
Catherine Drislane ◽  
Katie Lacy
Keyword(s):  
Skin Lesions ◽  
Malignant Skin

Common Benign and Malignant Skin Lesions

2001 ◽  
pp. 867-884
Author(s):  
Maryam M. Asgari ◽  
David J. Leffell
Keyword(s):  
Skin Lesions ◽  
Malignant Skin

scholarly journals Teaching Skin Cancer Detection to Medical Students Using a Dermoscopic Algorithm

PRiMER ◽  
2021 ◽  
Vol 5 ◽  
Author(s):  
Peggy R. Cyr ◽  
Wendy Craig ◽  
Hadjh Ahrns ◽  
Kathryn Stevens ◽  
Caroline Wight ◽  
...  
Keyword(s):  
Primary Care ◽  
Medical Students ◽  
Skin Cancer ◽  
Primary Care Physicians ◽  
Survival Rates ◽  
Family Physicians ◽  
Skin Lesions ◽  
Posttest Score ◽  
Malignant Skin ◽  
Attending Physicians

Introduction: Early detection of melanoma skin cancer improves survival rates. Training family physicians in dermoscopy with the triage amalgamated dermoscopic algorithm (TADA) has high sensitivity and specificity for identifying malignant skin neoplasms. In this study we evaluated the effectiveness of TADA training among medical students, compared with practicing clinicians. Methods: We incorporated the TADA framework into 90-minute workshops that taught dermoscopy to family physicians, primary care residents, and first- and second-year medical students. The workshop reviewed the clinical and dermoscopic features of benign and malignant skin lesions and included a hands-on interactive session using a dermatoscope. All participants took a 30-image pretest and a different 30-image posttest. Results: Forty-six attending physicians, 25 residents, and 48 medical students participated in the workshop. Mean pretest scores were 20.1, 20.3, and 15.8 for attending physicians, resident physicians and students, respectively (P&lt;.001); mean posttest scores were 24.5, 25.9, and 24.1, respectively (P=.11). Pre/posttest score differences were significant (P&lt;.001) for all groups. The medical students showed the most gain in their pretest and posttest scores. Conclusion: After short dermoscopy workshop, medical students perform as well as trained physicians in identifying images of malignant skin lesions. Dermoscopy training may be a valuable addition to the medical school curriculum as this skill can be used by primary care physicians as well as multiple specialists including dermatologists, gynecologists, otolaryngologists, plastic surgeons, and ophthalmologists, who often encounter patients with concerning skin lesions.

scholarly journals Malignant skin lesions in Oshogbo, Nigeria

2015 ◽  
Vol 20 ◽  
Author(s):  
Ganiyu Oyediran Oseni ◽  
Peter Babatunde Olaitan ◽  
Akinwumi Oluwole ◽  
Olaejirinde Olaniyi Olaofe ◽  
Hezekiah Adebola Morakinyo ◽  
...  
Keyword(s):  
Skin Lesions ◽  
Malignant Skin

Chemical and Laser Resurfacing of the Eyelids and Face

2011 ◽  
Author(s):  
John B. Holds
Keyword(s):  
Sun Exposure ◽  
Skin Lesions ◽  
Healing Time ◽  
Skin Type ◽  
Skin Resurfacing ◽  
Skin Preparation ◽  
Type Iv ◽  
Malignant Skin ◽  
Chemical Peels ◽  
History Of

Chemical peels, mechanical abrasion, and more recently laser and electrosurgical devices are used to resurface eyelid and facial skin. The common feature in these techniques is the denaturation or removal of the skin surface. These techniques typically help to hide skin changes related to sun exposure and aging by evening the skin tone, decreasing dyschromia, and diminishing wrinkles. These techniques all require careful case selection and patient preparation with appropriate treatment and postoperative care. Recent interest has focused on less invasive therapy with techniques that leave the epithelium largely intact, shortening healing time and reducing the risk of complications. Aging and sun damage induce a number of changes in skin, including wrinkling, the development of muscle- or gravity-related folds, irregular pigment or dyschromia, and the growth of benign and malignant skin lesions. Scars from acne, trauma, or surgery can also be indications for skin resurfacing. Potential benefit in all of these techniques must be balanced against risks and expected healing time. A medical history must be obtained, looking for a history of immune dysfunction, prior acne, or a history of herpes simplex outbreaks. Prior treatment with radiation or isotretinoin (Accutane) may diminish the pilosebaceous units required for healing. Acne rosacea and cutaneous telangiectasia may be aggravated by skin resurfacing. Cutaneous history must focus on scarring tendencies such as keloid formation, skin type, and ancestry. In particular, one must determine the patient’s skin type, most commonly by assigning a Fitzpatrick’s skin type. Patients with skin type III require careful topical preparation for skin resurfacing treatment in most cases, and patients with skin type IV or higher are more prone to scarring and pigment issues and are not treated with medium depth to deep skin resurfacing techniques by most clinicians. Wrinkles may be graded by the Glogau classification scheme. This scale from “fine wrinkles” (type 1) to “only wrinkles” (type IV) will help to define the amount and type of treatment needed. These loose recommendations will generally hold true in determining effective therapy. The deeper and more invasive the treatment, the more important the role of skin preparation and prophylaxis.

Comparing the capabilities of transfer learning models to detect skin lesion in humans

2020 ◽  
Vol 234 (10) ◽  
pp. 1083-1093 ◽  
Author(s):  
Aditi Singhal ◽  
Ramesht Shukla ◽  
Pavan Kumar Kankar ◽  
Saurabh Dubey ◽  
Sukhjeet Singh ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Transfer Learning ◽  
Wiener Filter ◽  
Skin Lesions ◽  
Automated Classification ◽  
Convolutional Networks ◽  
Image Quantization ◽  
Malignant Skin ◽  
Effective Diagnosis

Effective diagnosis of skin tumours mainly relies on the analysis of the characteristics of the lesion. Automatic detection of malignant skin lesion has become a mandatory task to reduce the risk of human deaths and increase their survival. This article proposes a study of skin lesion classification using transfer learning approach. The transfer learning model uses four different state-of-the-art architectures, namely Inception v3, Residual Networks (ResNet 50), Dense Convolutional Networks (DenseNet 201) and Inception Residual Networks (Inception ResNet v2). These models are trained under the dataset comprising seven different classes of skin lesions. The skin lesion images are pre-processed using image quantization, grayscaling and the Wiener filter before final training step. These models are compared for performance evaluation on different metrics. The present study shows the efficacy of the methodology for automated classification of lesion images.

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