scholarly journals Predictors of heart failure in patients treated with primary PCI for acute myocardial infarction: Short term 30-days follow-up

2011 ◽  
Vol 30 (4) ◽  
pp. 27-34
Author(s):  
Ivana Nedeljković ◽  
Miodrag Ostojić ◽  
Bosiljka Vujisić-Tešić ◽  
Branko Jakovljević ◽  
Milan Petrović ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Acute Myocardial Infarction ◽  
Primary Pci ◽  
Short Term

Long-term impact of new-onset atrial fibrillation complicating acute myocardial infarction on heart failure: insights from the NOAFCAMI-SH registry

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S.L Xu ◽  
J Luo ◽  
H.Q Li ◽  
Z.Q Li ◽  
B.X Liu ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Myocardial Infarction ◽  
Natural Science ◽  
Funding Source ◽  
Onset Atrial Fibrillation ◽  
New Onset

Abstract Background New-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) has been associated with poor survival, but the clinical implication of NOAF on subsequent heart failure (HF) is still not well studied. We aimed to investigate the relationship between NOAF following AMI and HF hospitalization. Methods This retrospective cohort study was conducted between February 2014 and March 2018, using data from the New-Onset Atrial Fibrillation Complicating Acute Myocardial Infarction in ShangHai registry, where all participants did not have a documented AF history. Patients with AMI who discharged alive and had complete echocardiography and follow-up data were analyzed. The primary outcome was HF hospitalization, which was defined as a minimum of an overnight hospital stay of a participant who presented with symptoms and signs of HF or received intravenous diuretics. Results A total of 2075 patients were included, of whom 228 developed NOAF during the index AMI hospitalization. During up to 5 years of follow-up (median: 2.7 years), 205 patients (9.9%) experienced HF hospitalization and 220 patients (10.6%) died. The incidence rate of HF hospitalization among patients with NOAF was 18.4% per year compared with 2.8% per year for those with sinus rhythm. After adjustment for confounders, NOAF was significantly associated with HF hospitalization (hazard ratio [HR]: 3.14, 95% confidence interval [CI]: 2.30–4.28; p<0.001). Consistent result was observed after accounting for the competing risk of all-cause death (subdistribution HR: 3.06, 95% CI: 2.18–4.30; p<0.001) or performing a propensity score adjusted multivariable model (HR: 3.28, 95% CI: 2.39–4.50; p<0.001). Furthermore, the risk of HF hospitalization was significantly higher in patients with persistent NOAF (HR: 5.81; 95% CI: 3.59–9.41) compared with that in those with transient NOAF (HR: 2.61; 95% CI: 1.84–3.70; p interaction = 0.008). Conclusion NOAF complicating AMI is strongly associated with an increased long-term risk of heart. Cumulative incidence of outcome Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): 1. National Natural Science Foundation of China, 2. Natural Science Foundation of Shanghai

D-dimer and the incidence of heart failure and mortality after acute myocardial infarction

Heart ◽  
2020 ◽  
pp. heartjnl-2020-316880 ◽  
Author(s):  
Xiaoyuan Zhang ◽  
Shanjie Wang ◽  
Jinxin Liu ◽  
Yini Wang ◽  
Hengxuan Cai ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Acute Myocardial Infarction ◽  
Plaque Rupture ◽  
Risk Of Death ◽  
Increased Risk ◽  
Clinical Covariates ◽  
All Cause Mortality ◽  
D Dimer

ObjectiveD-dimer might serve as a marker of thrombogenesis and a hypercoagulable state following plaque rupture. Few studies explore the association between baseline D-dimer levels and the incidence of heart failure (HF), all-cause mortality in an acute myocardial infarction (AMI) population. We aimed to explore this association.MethodsWe enrolled 4504 consecutive patients with AMI with complete data in a prospective cohort study and explored the association of plasma D-dimer levels on admission and the incidence of HF, all-cause mortality.ResultsOver a median follow-up of 1 year, 1112 (24.7%) patients developed in-hospital HF, 542 (16.7%) patients developed HF after hospitalisation and 233 (7.1%) patients died. After full adjustments for other relevant clinical covariates, patients with D-dimer values in quartile 3 (Q3) had 1.51 times (95% CI 1.12 to 2.04) and in Q4 had 1.49 times (95% CI 1.09 to 2.04) as high as the risk of HF after hospitalisation compared with patients in Q1. Patients with D-dimer values in Q4 had more than a twofold (HR 2.34; 95% CI 1.33 to 4.13) increased risk of death compared with patients in Q1 (p<0.001). But there was no association between D-dimer levels and in-hospital HF in the adjusted models.ConclusionsD-dimer was found to be associated with the incidence of HF after hospitalisation and all-cause mortality in patients with AMI.

One-year follow-up results from the randomised study STEP IN AMI (Short Term Psychotherapy In Acute Myocardial Infarction)

2012 ◽  
Vol 4 ◽  
pp. 58-59 ◽  
Author(s):  
Roncella Adriana ◽  
Pristipino Christian ◽  
Pasceri Vincenzo ◽  
Scorza Silvia ◽  
Cianfrocca Cinzia ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Short Term ◽  
Randomised Study ◽  
One Year

scholarly journals A prolonged follow-up of patients with acute myocardial infarction with using aldosterone antagonists

2013 ◽  
Vol 17 (2 (66)) ◽  
pp. 132-136
Author(s):  
V. K. Tashchuk ◽  
O. S. Polianska ◽  
O. I. Gulaga
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Acute Myocardial Infarction ◽  
Left Ventricle ◽  
Ejection Fraction ◽  
Functional Condition ◽  
Plasma Aldosterone ◽  
Aldosterone Antagonists ◽  
S Factor

We have carried out an analysis of longterm results of using aldosterone antagonists (spironolactone and eplerenone) in a holiatry of patients with myocardial infacrtion and heart failure. The functional condition of the myocardium has been investigated by means of electrocardiography, the level of the neurohumoral messengers – aldosterone, angiotensin-converting enzym, atrial natriuretic peptide, Willebrand`s factor has been determined. It has been demonstrated that with the use of eplerenone there exists a higher probability of restoring the functional state of the myocardium in patients – an increase of the ejection fraction by 16,1 %, the stroke volume by 23,2 %. According to the theory of chances it has been established that, while using eplerenone, the likelihood of achieving the mass of the myocardium of the left ventricle less than 180,24±15,24 g is sighnificantly higher than the use of spironolactone (t=2,10, р<0,05). While analyzing the concentration of the blood plasma aldosterone it was establishes that in a year its content essentially decreased in both groups, although it was more marked in persons who took eplerenone (р<0,01).

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