Comparison of Non-diabetic Young Adults with and without Parental History of Diabetes Mellitus for Heart Rate Recovery

2017 ◽  
Vol 11 (3) ◽  
pp. 187
Author(s):  
Akansha Sikarwar ◽  
Richa Rai ◽  
V P Gupta ◽  
Priyanka Chugh ◽  
Y P Munjal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Young Adults ◽  
Heart Rate Recovery ◽  
Parental History ◽  
History Of ◽  
Parental History Of Diabetes

scholarly journals Association of Autonomic imbalance with Parental history of Type 2 Diabetes Mellitus

2020 ◽  
Vol 11 (3) ◽  
pp. 67-70
Author(s):  
Satyajit Bagudai ◽  
Hari Prasad Upadhyay
Keyword(s):  
Diabetes Mellitus ◽  
Heart Rate ◽  
Heart Rate Recovery ◽  
Step Test ◽  
Parental History ◽  
Type2 Diabetes ◽  
Diabetic Children ◽  
History Of ◽  
Parental History Of Diabetes

Background: Off springs with a parental history of type 2 diabetes mellitus are genetically susceptible to develop diabetes. In some recent reports it has been shown that these vulnerable population exhibit altered autonomic activity even before the manifestations of disease. Autonomic dysfunction might be the initial cardiac pathology in subclinical type2 diabetes. Till now very few studies have been done to find out the early outcomes of this genetic transmission. Keeping in view of the above facts, the current study was carried out to find out the association between autonomic dysfunction and parental history of diabetes. Aim and Objectives: This study was aimed to quantify and compare the difference (if any) of heart rate recovery in response to 3minute step test between the young non diabetic children of non-diabetic and diabetic parents. Materials and Methods: Fifty-one non diabetic students were divided into two groups. One group comprised of students with parental history of type2 diabetes mellitus and another group with students without parental history of diabetes. Each student was subjected to 3minute Master step test. Recordings of heart rate were made before and after exercise. Heart arte recovery (HRR) in 1 minute (HRR1) as well as in 2, 3 and 4 minute (HRR2,HRR3, HRR4) were recorded and analyzed. Results: The resting (basal) as well as 1stminute heart rate recovery (HRR1) was not significantly different between the two groups. Likewise, the 2nd minute HRR (HRR2), 3rd minute HRR (HRR3) and 4th minute HRR (HRR4) respectively were also not significantly different between the two groups. Conclusion: This study concludes that there is no difference in the heart rate recovery in response to the exercise stress test between the young non diabetic children of non-diabetic and diabetic parents. Therefore, parental history of diabetes does not have any impact on the cardiovascular autonomic activity before the disease manifestation.

scholarly journals Comparison of heart rate recovery between normotensive young adults with and without a parental history of hypertension

2020 ◽  
Vol 11 (3) ◽  
pp. 31-36
Author(s):  
Satyajit Bagudai ◽  
Hari Prasad Upadhyay
Keyword(s):  
Heart Rate ◽  
Young Adults ◽  
Heart Rate Recovery ◽  
Step Test ◽  
Exercise Heart Rate ◽  
Parental History ◽  
Recovery Index ◽  
Significant Difference ◽  
History Of ◽  
The Difference

Introduction: Studies have reported that off springs of hypertensive parents are more likely to develop hypertension. Affection of target organ starts even before the diagnosis of hypertension. Autonomic dysfunction may be the initial cardiac effects in the pathogenesis of hypertension. Till now very few studies have been done to find the early outcomes in the cardiac autonomic functions in the normotensive siblings of hypertensive patients. Heart rate recovery after exercise is a useful marker for cardiac autonomic function. Since the etio-pathogenesis of hypertension is expected to affect the autonomic cardiovascular parameters even before the prehypertensive stage, the following study was carried out to analyze the heart rate recovery, in the descendent non- hypertensive young adults with and without parental history of hypertension. Aim and objective: This research study was aimed to study the quantify and compare the difference (if any) of heart rate recovery in response to 3minute step test between non hypertensive children of non- hypertensive and hypertensive parents within an age group of 18-22 years. Material &Methods: A total of 63 normotensive students were divided into one hypertensive parents(HP) group containing students with parental history of hypertension) and one non hypertensive parents group (NHP) having students without parental history of hypertension). Each student was subjected to 3 minute Master step test. Recordings of heart rate were made before and after exercise. Heart rate recovery index (HRRI) of 1minute (HRRI1), as well as in 2, 3 and 4 minute (HRRI2, HRRI3, HRRI4) were calculated and analyzed. Results: The resting (basal) heart rate as well as 1st minute heart rate recovery index (HRRI1) was not significantly different in the two groups. Likewise, the 2nd minute (HRRI2), 3rd minute (HRRI3), and 4th minute HRRI (HRR4) respectively were also not significantly different between the two groups. Conclusion: This study concluded that there is no significant difference in heart rate recovery among non-hypertensive young adults, with and without parental history of hypertension.

Parental history of diabetes mellitus has additive risk of metabolic syndrome in patients treated with clozapine

2020 ◽  
Vol 50 ◽  
pp. 101939
Author(s):  
Yanzhi Zeng ◽  
Shengyun Chen ◽  
Dennis Liu ◽  
Lisa Hahn ◽  
Xiaowei Xia ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Parental History ◽  
History Of ◽  
Additive Risk ◽  
Parental History Of Diabetes

scholarly journals RELATIONSHIP BETWEEN PARENTAL HISTORY OF TYPE 2 DIABETES MELLITUS WITH THE SYMPATHOVAGAL BALANCE IN YOUNG ADULTS WITH COMPARABLE BMI, STRESS AND PHYSICAL ACTIVITY LEVELS

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Shakthinag S ◽  
Sandip Sardessai
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Heart Rate ◽  
Type 2 Diabetes Mellitus ◽  
Time Domain ◽  
P Value ◽  
Parental History ◽  
History Of

Background: With the heritability of Type 2 diabetes mellitus adding to the disease burden, it would be ideal to find screening tools to detect early changes that could be present in Euglycemic individuals with a genetic predisposition. Objective: To study if the parental history of type 2 diabetes mellitus has an association with the time domain, frequency domain and nonlinear basal heart rate variability indices Methods and material: Thiscross sectional study was conducted in the Physiology department of Goa Medical college over a period of 2 months on 70 Medical students between the age of 18-21 years, with low-moderate stress (PAS 10) and fair physical activity(PAI of American academy of health and fitness). Using an Inco Polyrite D instrument, data collection was done and the RR interval data was analysed using Kubios software for the basal Heart rate variability indices of time domain, frequency domain and nonlinear methods. Data was entered into Excel spreadsheet and analysed using SPSS version 14. Mann Whitney U test was done to test for statistical significance. Result: The mean age of the sample was 18.94± 0.759 years and out of the 70 subjects who had participated in the study 36 (51.4%) subjects had a positive parental family history of type 2 diabetes mellitus while 34 (48.6%) subjects did not. Significant changes were observed in the LF (nu), HF (nu) and LF/HF ratio. A significantly higher LF.n.u (p value - 0,008) and LF/HF (p value- 0.008) was observed in group with family history and a significantly lower HF.n.u ( p value – 0.007)was observed in the same group. No other significant changes were observed in time domain and non linear indices. Conclusion: Frequency domain HRV may be useful as a predictive index for diabetes mellitus. The presence of higher sympathetic activity and lower parasympathetic activity in individuals (with comparable stress level, BMI, physical activity) having a positive parental history of diabetes mellitus might indicate an underlying autonomic imbalance Keywords: Diabetes, Family history, Heart rate variability, HRV, parental history, Sympathovagal balance

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