Phenolic profile, Anti-inflammatory and Diuretic properties of Asplenium ceterach tested on Albino mice and Wistar albino rats

2020 ◽  
Vol 13 (6) ◽  
pp. 449-454
Author(s):  
Rekia Sidhoum ◽  
Mostapha Bachir bey ◽  
Latifa Halli ◽  
Othmane Yalaoui ◽  
Asma Belkadi
Keyword(s):  
Albino Rats ◽  
Phenolic Profile ◽  
Albino Mice ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

scholarly journals Analgesic and Anti-Inflammatory Activity of Total Crude Leaf Extract of <i>Phytolacca dodecandra</i> in Wistar Albino Rats

2019 ◽  
Vol 10 (03) ◽  
pp. 259-271
Author(s):  
Loyce Nakalembe ◽  
Josephine N. Kasolo ◽  
Edward Nyatia ◽  
Aloysius Lubega ◽  
Godfrey S. Bbosa
Keyword(s):  
Leaf Extract ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Phytolacca Dodecandra ◽  
Crude Leaf Extract ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

scholarly journals Antibacterial, Antioxidant and Anti-Inflammatory Potential of the Different Extracts of Holoptelia Integrifolia

2019 ◽  
Vol 9 (2) ◽  
pp. 5234-5240
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Inflammatory Activity ◽  
Diffusion Method ◽  
Albino Rats ◽  
Nitric Oxide Radical ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

Medicinal plants are play significant impact in the personal medicine for most of the people all over the world as an alternative live saving medicines and most of their medicinal properties are well known for anticancer activity. The different extracts of Holoptelea integrifolia (H.integrifolia) leaves, stem bark and fruits were studied as a potent natural source of antimicrobial, antioxidant and wound healing potential. This work was carried out to evaluate antimicrobial, antioxidant and anti-inflammatory activity of different extracts of H.integrifolia. The antimicrobial activity of the H.integrifolia ethanolic extract was studied against five fungal and bacterial strains by utilizing the agar well diffusion method and MIC. Among several strain, the ethanolic extract of fruit has shown higher antimicrobial inhibition zone as 9.25-16 mm compare to other two extracts of stem and leaves as 10- 13.25 mm and 6-10.2 mm respectively. The antioxidant activities for different extract were also determined by DPPH free radical assay, Hydroxyl Radical Scavenging and Nitric Oxide Radical Scavenging Activity method. The anti-inflammatory activity also estimated basedon formalin induced paw edema method on Wistar albino rats. The different extracts of leaves, stem bark and fruit parts of Holoptelea integrifolia were estimated for in vivo anti-inflammatory activity against the animal model of female Wistar albino rats. The results of anti-inflammatory activity revealed that the Ethanol extracts showed vital and dose-dependent anti-inflammatory effects. Our findings revealed that aerial parts of H.integrifolia contais potential antimicrobial, antioxidant and anti-inflammatory compounds, which expose the medicinal potential of the selected plant could be a significant drug candidates against microbial, oxidative and inflammation-related pathological processes as a future alternative medicine.

scholarly journals PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF AERIAL PART EXTRACTS OF PLANTAGO MAJOR L.

2017 ◽  
Vol 10 (9) ◽  
pp. 307
Author(s):  
Jyoti Vandana ◽  
Gupta A K ◽  
Alok Mukerjee
Keyword(s):  
Aerial Part ◽  
Iridoid Glycosides ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Plantago Major ◽  
Phytochemical Screening ◽  
Paw Edema ◽  
Edema Model ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

  Objective: This study aims to perform phytochemical screening and investigate anti-inflammatory activity of extract from aerial part of the plant Plantago major L.Methods: Preliminary phytochemical screening of plant extract was carried out using standard qualitative procedures and anti-inflammatory activity was evaluated using carrageenan-induced paw edema model in male Wistar albino rats using plethysmometer. Diclofenac sodium (10 mg/kg, b.w.) was used as standard drug.Results: Preliminary phytochemical screening of the different extracts revealed that they were rich in secondary metabolite compounds such as carbohydrates, tannins, steroids, flavonoids, terpenoids, glycosides, fats and oils, alkaloids, phenolic compounds, and iridoid glycosides. The anti-inflammatory activity was evaluated using carrageenan-induced paw edema models in Wistar albino rats. The anti-inflammatory activity of methanolic extract (ME) was found to be dose dependent in carrageenan-induced paw edema model. The ME has shown significant (p<0.05) inhibition of paw edema, 61.11% and 55.55% on 4th hr at the doses of 900 and 600 mg/kg, respectively.Conclusion: The results of the present study demonstrate that ME of the aerial parts of the plant possess significant (p<0.05) anti-inflammatory potential.

Antioxidant potential, anti-inflammatory activity and gastroprotective mechanisms of Mallotus roxburghianus (Muell.) against ethanol-induced gastric ulcers in Wistar albino rats

2017 ◽  
Vol 36 ◽  
pp. 448-458 ◽  
Author(s):  
Kumari Sagun ◽  
Vikas Kumar Roy ◽  
Ramaswamy Sathish Kumar ◽  
Kalibulla Syed Ibrahim ◽  
Thangaraj Parimelazhagan ◽  
...  
Keyword(s):  
Antioxidant Potential ◽  
Inflammatory Activity ◽  
Gastric Ulcers ◽  
Albino Rats ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

scholarly journals EXPERIMENTAL EVALUATION OF ANALGESIC AND ANTI INFLAMMATORY POTENTIAL OF LEAVES OF ANTIDESMA ACIDUM ON WISTAR ALBINO RATS

2014 ◽  
Vol 2 (1) ◽  
pp. 1-3
Author(s):  
Arathi Krishnan ◽  
Ravi Mundugaru ◽  
Suma Mallya ◽  
Sridhar Bairy ◽  
Ravishankar B
Keyword(s):  
Experimental Evaluation ◽  
Albino Rats ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF CURCUMIN WITH DIFFERENT NSAIDS

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (07) ◽  
pp. 72-76
Author(s):  
Navpreet Kaur ◽  
Sharanjit Kaur ◽  
Sumeet Gupta ◽  
Samrat Chauhan ◽  
Ipshita Chattopadhyaya
Keyword(s):  
Analgesic Activity ◽  
Albino Rats ◽  
Time Interval ◽  
Writhing Test ◽  
Analgesic Agents ◽  
Plantar Region ◽  
Anti Inflammatory ◽  
Wistar Albino Rats ◽  
Higher Doses ◽  
Acid Administration

The objective of this study was to investigate the anti-inflammatory and analgesic activity of curcumin with combination of different drugs using carrageenan induced paw edema model and writhing test in mice. Nimesulide and tenoxicam were administered orally at different doses of 2.5, 5.0 and 7.5 mg/kg and the lower doses of these drugs were also administered orally with curcumin 60 mg/kg. After, 1 hour 0.1 ml of carrageenan (i.e. 10 mg/ml) was injected into the sub-plantar region of right hind paw of the Wistar Albino rats (150-200g) and paw volume was measured after 30 mins 1 hr, 2 hr and 3 hr using a Plethysmometer. In analgesic activity, the drug ketorolac was used with combination of curcumin and number of writhes induced by glacial acetic acid administration in mice were observed. Administration of carrageenan produced significant edema in the hind paw of rats. The edema was found to be significantly inhibited by combination of curcumin 60 mg/kg and the lower doses of nimesulide & tenoxicam in different time interval and having comparable effects as of higher doses of these drugs. Similar results were also observed in analgesic activity. From this study it can be concluded that curcumin having synergistic effect when administered with combination different anti-inflammatory and analgesic agents.

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