scholarly journals The effect of antimicrobial photodynamic therapy against virulence genes expression in colistin-resistance Acinetobacter baumannii

LASER THERAPY ◽  
2019 ◽  
Vol 28 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Ebrahim Boluki ◽  
Maryam Moradi ◽  
Pardis Soleimanzadeh Azar ◽  
Reza Fekrazad ◽  
Maryam Pourhajibagher ◽  
...  
Nanomedicine ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. 437-452 ◽  
Author(s):  
Maryam Pourhajibagher ◽  
Alireza Partoazar ◽  
Mojgan Alaeddini ◽  
Shahroo Etemad-Moghadam ◽  
Abbas Bahador

Aim: To evaluate the antimicrobial effects of photoexcited silver sulfadiazine nanoliposomes (AgSD-NLs) doped by curcumin (AgSD-NLs@Cur) on Acinetobacter baumannii. Materials & methods: Following characterization, the cytotoxic and hemolytic activities of AgSD-NLs@Cur were evaluated. The antimicrobial activities of AgSD-NLs@Cur-mediated antimicrobial photodynamic therapy (aPDT) were determined. Histopathological examination of the burn wound sites of infected mice treated with photoexcited AgSD-NLs@Cur was assessed. Results: No significant cytotoxic and hemolytic activities were observed. There was a decrease in the Acinetobacter baumannii count in planktonic and biofilm forms and the gene expression level using AgSD-NLs@Cur-aPDT (p < 0.05). Histopathological analysis indicated the epidermis developed markedly and the bacterial load decreased significantly after aPDT. Conclusion: Photoexcited AgSD-NLs@Cur has an antimicrobial potential against A. baumannii.


2009 ◽  
Author(s):  
Tianhong Dai ◽  
George P. Tegos ◽  
Zongshun Lu ◽  
Timur Zhiyentayev ◽  
Liyi Huang ◽  
...  

2019 ◽  
Vol 34 (9) ◽  
pp. 1755-1761 ◽  
Author(s):  
Mirian Marcolan De Mello ◽  
Patrícia Pimentel De Barros ◽  
Renata de Cassia Bernardes ◽  
Silvio Rubens Alves ◽  
Naiara Pires Ramanzini ◽  
...  

Author(s):  
Pier Poli ◽  
Francisley Avila Souza ◽  
Mattia Manfredini ◽  
Carlo Maiorana ◽  
Mario Beretta

Not required for Clinical case letters according to the authors' guidelines.


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