ADC histogram analysis of MR imaging in the different diagnosis between benign and malignant tumors in the parapharyngeal space

Intraductal carcinomas are rare, malignant tumors that arise from the salivary glands. They commonly grow from the parotid gland and no cases growing from the parapharyngeal space have been reported to date. We report a 76-year-old man who was inadvertently found to have a parapharyngeal lesion by CT scans and MR imaging. The tumor was resected through an upper neck approach and diagnosed histopathologically as intraductal carcinoma. As far as we are aware, this is the first case of intraductal carcinoma arising from the parapharyngeal space. Here, we describe the management of this disease together with a review of the relevant literature.

Download Full-text

A comparative study of parapharyngeal space tumors over a 7 year period experience in tertiary care hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20182958 ◽

2018 ◽

Vol 4 (5) ◽

pp. 1167

Author(s):

Athiyaman K. ◽

Gowri Shankar M. ◽

Suresh V. ◽

Natarajan S. ◽

Malarvizhi R.

Keyword(s):

Parapharyngeal Space ◽

Malignant Tumors ◽

Tertiary Care ◽

Direct Access ◽

Vascular Lesions ◽

Care Hospital ◽

Neurogenic Tumors ◽

Parapharyngeal Space Tumors ◽

First Choice ◽

Cervical Approach

Background: Tumors of the parapharyngeal space (PPS) are rare, accounting for 0.5–1.5% of all head and neck tumors. The anatomy of the PPS is responsible for a wide variety of tumors arising from the PPS. Our series of 10 PPS tumors provides an overview of the clinical course and management of PPS tumors.Methods: This retrospective study included clinical data from patients treated for PPS tumors from 2011 to 2018 at the Stanley medical college hospital, Chennai. Results: After careful analysis of the outcome of the study, we have found out that there was no local recurrence in any patient during the follow-up period. Though few approaches are advised in the literature, In our study transoral approach may be advocated as the first choice for excision of parapharyngeal space tumors, except for malignant tumors and neurogenic tumor. Trans cervical approach is used for malignant and neurogenic tumors, considering its advantages of providing direct access to the neoplasm, adequate control of neurovascular structures from the neck.Conclusions: In our study, middle aged male population was most commonly affected. Pleomorphic adenoma is the most common PPS tumor; prestyloid compartment is mostly affected by these tumors. As per the previous studies, trans cervical approach is first choice for excision of parapharyngeal space tumors. In our study, trans oral approach is also a suitable, safe approach for pre styloid non vascular lesions and trancervical approach can be reserved for postsyloid and malignant lesions.

Download Full-text

Whole-Body MR Imaging for Staging of Malignant Tumors in Pediatric Patients: Results of the American College of Radiology Imaging Network 6660 Trial

Radiology ◽

10.1148/radiol.12112531 ◽

2013 ◽

Vol 266 (2) ◽

pp. 599-609 ◽

Cited By ~ 46

Author(s):

Marilyn J. Siegel ◽

Suddhasatta Acharyya ◽

Frederic A. Hoffer ◽

J. Brad Wyly ◽

Alison M. Friedmann ◽

...

Keyword(s):

Mr Imaging ◽

Pediatric Patients ◽

Malignant Tumors ◽

Whole Body

Download Full-text

Use-fullness of dynamic contrast-enhanced MR imaging and diffusion weighted MR imaging for differentiation of benign and malignant parotid tumors

10.36879/jcmi.18.000101 ◽

2018 ◽

pp. 1-6

Keyword(s):

Mr Imaging ◽

Malignant Tumors ◽

Dce Mri ◽

Dynamic Contrast Enhanced ◽

Parotid Tumors ◽

Contrast Enhanced ◽

Type C ◽

Sensitivity Specificity ◽

And Diffusion ◽

Malignant Parotid Tumors

Objectives: To evaluate the usefullness of dynamic contrast-enhanced MR Imaging (DCE-MRI) and diffusion weighted imaging (DWI) for differentiating benign from malignant parotid tumors. Methods: Prospectively,DCE-MRI and DWI were performed in 112 patients, with 148 confirmed parotid masses. The differential optimal thresholds were determined. Results: WConsidering tumors with time-intensity curve (TIC) Type C as malignant, sensitivity, specificity, accuracy were 95%, 76%, 79%, respectively. Considering ADC threshold values 0.709×10-3mm2 /s<ADC<0.948×10-3mm2 /s as malignant, sensitivity, specificity, accuracy were 75%, 78%, 78%, respectively. Considering TIC Type C and ADC values 0.709×10-3mm2 /s<ADC<0.948×10-3mm2 /s as malignant, sensitivity, specificity, accuracy were 75%, 91%, 89%, respectively. With threshold Kep<1.118 min-1 and Ve >0.315 between Warthin and malignant tumors, threshold Kep>0.555 min-1 and Ve <0.605 between pleomorphic adenomas and malignant tumors, sensitivity, specificity, accuracy for malignancy were 70% vs 90%, 96% vs 74%, 92% vs 80%, respectively. Conclusion: DCE-MRI and DWI provide more information in differentiating benign from malignant parotid tumors.

Download Full-text

Low Field Magnetic Resonance Imaging of Focal Hepatic Masses at 0.02 T

Acta Radiologica ◽

10.1177/028418518903000605 ◽

1989 ◽

Vol 30 (6) ◽

pp. 591-595

Author(s):

L. Ekelund ◽

L. Athlin

Keyword(s):

Magnetic Resonance ◽

Mr Imaging ◽

Malignant Tumors ◽

Signal To Noise Ratio ◽

Malignant Neoplasms ◽

Hepatic Hemangioma ◽

Resonance Imaging ◽

Benign Lesions ◽

Low Field ◽

Better Than

The diagnostic utility of extremely low field magnetic resonance (MR) imaging was evaluated in 25 patients with focal hepatic masses, including 17 with primary (n=7) or secondary (n= 10) malignant neoplasms and 8 with benign lesions (6 hemangiomas). The findings were compared with the results of computed tomography (CT). Out of 16 patients with malignant tumors demonstrated by both modalities, the diagnostic information from MR imaging was equal to or better than that from CT in 6 patients and inferior to CT in 10. Shortcomings of MR were mainly due to low signal-to-noise ratio and poor spatial resolution, resulting in an image quality inferior to that obtained at higher field strengths. Considering these facts, together with the long imaging times required, low field MR cannot be recommended for general use in the evaluation of hepatic masses. On the other hand, our results indicate that this technique may be useful in establishing the diagnosis of hepatic hemangioma.

Download Full-text