scholarly journals Intraductal Carcinoma of the Parotid Gland Presenting as Parapharyngeal Mass

2020 ◽  
Vol 5 (3) ◽  
pp. 1-7
Author(s):  
Yamato Oki ◽  
Hiromitsu Hatakeyama ◽  
Masako Otani ◽  
Hidetaka Ikemiyagi ◽  
Masanori Komatsu ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Parapharyngeal Space ◽  
Malignant Tumors ◽  
Relevant Literature ◽  
Ct Scans ◽  
Intraductal Carcinoma ◽  
First Case

Intraductal carcinomas are rare, malignant tumors that arise from the salivary glands. They commonly grow from the parotid gland and no cases growing from the parapharyngeal space have been reported to date. We report a 76-year-old man who was inadvertently found to have a parapharyngeal lesion by CT scans and MR imaging. The tumor was resected through an upper neck approach and diagnosed histopathologically as intraductal carcinoma. As far as we are aware, this is the first case of intraductal carcinoma arising from the parapharyngeal space. Here, we describe the management of this disease together with a review of the relevant literature.

Lymphoepithelial Carcinoma of the Parotid Glands and Its Relationship With Benign Lymphoepithelial Lesions

2008 ◽  
Vol 132 (2) ◽  
pp. 278-282 ◽  
Author(s):  
Manuela Schneider ◽  
Clara Rizzardi
Keyword(s):  
Parotid Gland ◽  
Salivary Glands ◽  
Malignant Tumors ◽  
Current Knowledge ◽  
Correct Diagnosis ◽  
Lymphocytic Infiltration ◽  
Lymphoepithelial Carcinoma ◽  
Parotid Glands ◽  
Neck Tumors ◽  
Lymphoepithelial Lesions

Abstract The salivary glands, despite their relatively simple morphology, give rise to more than 30 histologically distinct benign and malignant tumors. Salivary gland neoplasms comprise less than 2% of all tumors in humans and 3% of all head and neck tumors. They arise in the parotid gland in 80% of cases, and approximately 80% are benign and 20% are malignant. Among them are lymphoepithelial lesions, rare lesions of the salivary glands and especially of the parotid gland that are characterized by lymphocytic infiltration associated with an epithelial proliferation. They are divided into benign, which is considered as a tumorlike condition, and malignant, which is a rare carcinoma of the salivary glands. This article provides a review of the current knowledge on lymphoepithelial carcinoma with a look at its association with benign lesions and on the importance of making the correct diagnosis for the appropriate treatment.

scholarly journals Primary First Bite Syndrome of the Parotid Gland: Case Report and Literature Review

2020 ◽  
pp. 014556132096258
Author(s):  
Xia Yang ◽  
Xinjie Yang ◽  
Weiqi Wang ◽  
Pu Zhang ◽  
Rui Hou ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Unusual Case ◽  
Parapharyngeal Space ◽  
Malignant Tumors ◽  
Pathological Examination ◽  
Inclusion Criteria ◽  
Temporal Fossa ◽  
Deep Lobe ◽  
Surgical History ◽  
First Bite Syndrome

Objective: A case of primary first bite syndrome (FBS), diagnosed in a patient with nonspecific adenocarcinoma of the deep lobe of the parotid gland. Data Sources: A Medline literature search was conducted on PubMed, using the keywords “first bite syndrome.” Review Methods: Using primary FBS and existence of a definite etiology as inclusion criteria. Results: We report on an unusual case of primary FBS, which had no surgical history. After multiple examinations, the pain was localized to a mass in the deep lobe of the parotid gland. After tumorectomy, the FBS pain was significantly relieved. The postoperative pathological examination determined that the excised mass was a nonspecific adenocarcinoma. Reviewing the literature, we found that primary FBS was mostly caused by malignant tumors in the inferior temporal fossa, the deep lobe of the parotid gland, and (or) the parapharyngeal space. Surgery was reported to be an effective treatment. Conclusion: The case highlights the critical importance of identifying the etiology of primary FBS. When manifested with a primary FBS, malignant tumors must be high on the differential diagnosis list, especially those in the region of the inferior temporal fossa, the deep lobe of the parotid gland, and the parapharyngeal space.

ADC histogram analysis of MR imaging in the different diagnosis between benign and malignant tumors in the parapharyngeal space

Toukeibu Gan ◽  
2020 ◽  
Vol 46 (3) ◽  
pp. 248-253
Author(s):  
Natsuko Kunimatsu ◽  
Koki Miura ◽  
Yuichiro Tada ◽  
Tatsuo Masubuchi ◽  
Chihiro Fushimi ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Parapharyngeal Space ◽  
Malignant Tumors ◽  
Histogram Analysis

scholarly journals Spectrum of primary epithelial tumors of major salivary glands: a 5 year record based descriptive study from a tertiary care centre

2017 ◽  
Vol 4 (2) ◽  
pp. 562
Author(s):  
Jayalakshmy Payippat Leelamma ◽  
Bhavya P. Mohan
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Malignant Tumors ◽  
Tertiary Care ◽  
Benign Tumors ◽  
Care Centre ◽  
Tertiary Care Centre

Background: Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant epithelial tumors of major salivary glands in South India.Methods: This is a retrospective study in a tertiary care centre in Kerala, South India. A total of 180 epithelial neoplasms of major salivary gland were studied over a 5 year period. In each case age, sex, anatomical location and histopathological diagnosis were recorded.Results: Patients with benign and malignant tumors presented with a mean age of 52.3 and 55.9 years respectively. The frequency of benign tumors was 80.6% (n = 145) and of malignant tumors was 19.4% (n = 35). There was a higher prevalence of tumors in males 60.6% (n = 109) than in females 39.4% (n = 71). 91.9% (n = 164) of the tumors were localized in the parotid gland, 8.3% (n = 15) in the submandibular gland and 0.6% (n = 1) in the sublingual gland. The most common benign tumors were Pleomorphic adenoma (48.9%, n = 88) and Warthin’s tumor (28.9%, n = 52). Among malignant tumors, Mucoepidermoid carcinoma was the most common (9.5%, n = 17) followed by Carcinoma ex pleomorphic adenoma (2.8%, n = 5) and adenoid cystic carcinoma (2.2%, n = 4).Conclusions: Parotid gland was the most common site of both benign and malignant tumours. Plemorphic adenoma was the most common benign tumor and mucoepidermoid carcinoma was the most common malignant tumor.

Tuberous sclerosis with primary meningioma of the maxillary antrum

1991 ◽  
Vol 105 (6) ◽  
pp. 481-483 ◽  
Author(s):  
R. M. Irving ◽  
G. R. Ford ◽  
N. S. Jones
Keyword(s):  
Connective Tissue ◽  
Parotid Gland ◽  
Tuberous Sclerosis ◽  
Paranasal Sinuses ◽  
Autosomal Dominant ◽  
Parapharyngeal Space ◽  
Maxillary Antrum ◽  
First Case ◽  
Neurocutaneous Syndrome

AbstractPrimary extracranial meningiomas are uncommon; they have been documented in the ear, skin, orbit, parapharyngeal space, parotid gland, mediastinum, and rarely the paranasal sinuses. Tuberoussclerosis is an autosomal dominant neurocutaneous syndrome characterized by multiple connective tissue tumours. We report the first case of a tuberous sclerosis patient with a maxillary antral meningioma.

Complete recovery following transorbital penetrating head injury traversing the brainstem: case report

2019 ◽  
Vol 24 (6) ◽  
pp. 697-701 ◽  
Author(s):  
Mark A. MacLean ◽  
Karim Mukhida ◽  
Jai J. S. Shankar ◽  
Matthias H. Schmidt ◽  
David B. Clarke
Keyword(s):  
Head Injuries ◽  
Relevant Literature ◽  
Subsequent Development ◽  
Complete Recovery ◽  
Endovascular Embolization ◽  
Ophthalmological Examination ◽  
Trauma Resuscitation ◽  
Retained Foreign Body ◽  
First Case ◽  
Initial Injury

Transorbital penetration accounts for one-quarter of the penetrating head injuries (PHIs) in adults and half of those in children. Injuries that traverse (with complete penetration of) the brainstem are often fatal, with survivors rarely seen in clinical practice. Here, the authors describe the case of a 16-year-old male who suffered and recovered from an accidental transorbital PHI traversing the brainstem—the first case of complete neurological recovery following such injury. Neuroimaging captured the trajectory of the initial injury. A delayed-onset carotid cavernous fistula and the subsequent development of internal carotid artery pseudoaneurysms were managed by endovascular embolization.The authors also review the relevant literature. Sixteen cases of imaging-confirmed PHI traversing the brainstem have been reported, 14 involving the pons and 12 penetrating via the transorbital route. Management and outcome of PHI are informed by object velocity, material, entry point, trajectory, relationship to neurovascular structures, and the presence of a retained foreign body. Trauma resuscitation is followed by a careful neurological examination and appropriate neuroimaging. Ophthalmological examination is performed if transorbital penetration is suspected, as injuries may be occult; the potential for neurovascular complications highlights the value of angiography. The featured case shows that complete recovery is possible following injury that traverses the brainstem.

Novel Coronavirus Disease (COVID-19): A Narrative Review Based on Current Status

2020 ◽  
Vol 18 ◽  
Author(s):  
Rina Das ◽  
Dinesh Kumar Mehta ◽  
Meenakshi Dhanawat
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Clinical Symptoms ◽  
Virus Disease ◽  
Relevant Literature ◽  
World Health ◽  
Current Status ◽  
Future Research ◽  
Treatment And Prevention ◽  
First Case ◽  
Novel Coronavirus

Abstract:: A novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), appeared and expanded globally by the end of year in 2019 from Wuhan, China, causing severe acute respiratory syndrome. During its initial stage, the disease was called the novel coronavirus (2019-nCoV). It was named COVID-19 by the World Health Organization (WHO) on 11 February 2020. The WHO declared worldwide the SARS-CoV-2 virus a pandemic on March 2020. On 30 January 2020 the first case of Corona Virus Disease 2019 (COVID-19) was reported in India. Now in current situation the virus is floating in almost every part of the province and rest of the globe. -: On the basis of novel published evidences, we efficiently summarized the reported work with reference to COVID-19 epidemiology, pathogen, clinical symptoms, treatment and prevention. Using several worldwide electronic scientific databases such as Pubmed, Medline, Embase, Science direct, Scopus, etc were utilized for extensive investigation of relevant literature. -: This review is written in the hope of encouraging the people successfully with the key learning points from the underway efforts to perceive and manage SARS-CoV-2, suggesting sailent points for expanding future research.

Primary stromal sarcoma of breast: A case report and literature review

2021 ◽  
pp. 1-7
Author(s):  
Mohammad Al-Wiswasy ◽  
Mahmoud Al-Balas ◽  
Raith Al-Saffar ◽  
Hamzeh Al-Balas
Keyword(s):  
Malignant Tumors ◽  
Histopathological Examination ◽  
Prognostic Significance ◽  
Total Duration ◽  
Young Patients ◽  
Soft Tissue Sarcomas ◽  
Breast Mass ◽  
Resection Margins ◽  
Stromal Sarcoma ◽  
First Case

INTRODUCTION: Primary breast sarcoma (PBS) was first described in 1887 as a rare heterogeneous neoplasm arising from the mesenchymal tissue of the mammary gland accounting for less than 5% of all body soft-tissue sarcomas and less than 0.1% of all malignant tumors of the breast. CASE PRESENTATION: A 31-year old lady presented with left breast mass which she felt four years before during which the mass increased in size from 1 to 6 cm in the largest diameter, diagnosed clinically as a benign fibroadenoma without any further cytological or histopathological confirmation. Histopathological examination of the excised breast mass reveals undifferentiated, primary stromal sarcoma of the breast (PSSB), which was followed by mastectomy three weeks later with reconstructive breast surgery with a total duration of follow-up of 3 years thereafter. This is the first case of PSSB reported in Jordan. DISCUSSION/CONCLUSION: PSSB is the generic term given to malignant breast tumors thought to arise from the specialized mesenchymal stroma of the breast but lacking an epithelial component with a phylloides pattern. PSSB is difficult to diagnose preoperatively due to its rarity and inadequate imaging methods to establish an exact diagnosis. The histology of the patient mass may be the leading factor for the management of these tumors. Even in very young patients, a progressively growing breast mass should alert the clinician to investigate for malignancy and verify the results by biopsy. Surgery with adequate resection margins represents the only potentially curative modality with prognostic significance. Adjuvant chemotherapy and radiotherapy are not very beneficial. The prognosis is dismal for patients with lymph node involvement and the size of the tumor has a lesser bearing on the outcome.

Penile Lymphoepithelioma-Like Carcinoma: A Rare Case With PD-L1 Expression

2021 ◽  
pp. 106689692098834
Author(s):  
Raquel Machado-Neves ◽  
Bernardo Teixeira ◽  
Elsa Fonseca ◽  
Pedro Valente ◽  
Joaquim Lindoro ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Tumor Cells ◽  
Rare Case ◽  
Malignant Tumors ◽  
Squamous Cell Carcinomas ◽  
The Third ◽  
The Past ◽  
First Case ◽  
Lymphoplasmacytic Infiltrate

Most malignant tumors of the penis are squamous cell carcinomas (SCC), being divided in 2 groups, one human papillomavirus (HPV)-related and another non-HPV-related, with lymphoepithelioma-like carcinoma (LELC) being one of the rarest HPV-related SCC. In this article, we report a case of a 50-year-old man who presented testicular swelling and pain for the past 3 months. A penile mass was identified, and the patient was submitted to a total penectomy. The penectomy specimen showed an ulcerated lesion at the glans reaching the cavernous bodies. Microscopic examination showed undifferentiated epithelial cells with syncytial growth pattern mix with a dense lymphoplasmacytic infiltrate, consistent with LELC. The tumor cells expressed p16 and all 3 different clones of PDL1 (22C3, SP263, and SP142). The patient is alive and well with a follow-up of 3 months. To our knowledge, this is the third LELC of the penis reported in literature and the first case reported with PDL1 expression.

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