scholarly journals Reproducibility of tapping rhythm in young and elderly subjects

1991 ◽  
Vol 9 ◽  
pp. 21-26
Author(s):  
Tooru Nagasawa ◽  
Satoshi Kurata ◽  
Yasuhiko Abe ◽  
Yoshitaka Yuasa ◽  
Kazuhiro Tsuga ◽  
...  
2010 ◽  
Vol 43 (15) ◽  
pp. 2999-3006 ◽  
Author(s):  
Benoit Mariani ◽  
Constanze Hoskovec ◽  
Stephane Rochat ◽  
Christophe Büla ◽  
Julien Penders ◽  
...  

1988 ◽  
Vol 17 (1) ◽  
pp. 35-41 ◽  
Author(s):  
R. J. NEALE ◽  
H. LIM ◽  
JULIE TURNER ◽  
C. FREEMAN ◽  
J. R. KEMM

1994 ◽  
Vol 37 (3) ◽  
pp. 662-670 ◽  
Author(s):  
Peter J. Fitzgibbons ◽  
Sandra Gordon-Salant

This study examined auditory temporal sensitivity in young adult and elderly listeners using psychophysical tasks that measured duration discrimination. Listeners in the experiments were divided into groups of young and elderly subjects with normal hearing sensitivity and with mild-to-moderate sloping sensorineural hearing loss. Temporal thresholds in all tasks were measured with an adaptive forced-choice procedure using tonal stimuli centered at 500 Hz and 4000 Hz. Difference limens for duration were measured for tone bursts (250 msec reference duration) and for silent intervals between tone bursts (250 msec and 6.4 msec reference durations). Results showed that the elderly listeners exhibited diminished duration discrimination for both tones and silent intervals when the reference duration was 250 msec. Hearing loss did not affect these results. Discrimination of the brief temporal gap (6.4 msec) was influenced by age and hearing loss, but these effects were not consistent across all listeners. Effects of stimulus frequency were not evident for most of the duration discrimination conditions.


1991 ◽  
Vol 261 (2) ◽  
pp. E252-E256 ◽  
Author(s):  
B. A. Clark ◽  
D. Elahi ◽  
L. Fish ◽  
M. McAloon-Dyke ◽  
K. Davis ◽  
...  

Atrial natriuretic peptide (ANP) may suppress vasopressin release, but the dynamics of this interaction as well as the influence of age have not been defined. We studied six or seven young (19-40 yr old) and seven elderly volunteers (65-83 yr old) under two circumstances: 1) after infusion of 5% saline (0.04 ml.kg-1.min-1) for 2 h and 2) after the same infusion given with simultaneous synthetic human ANP (0.05 micrograms.kg-1.min-1). Hypertonic saline alone produced a progressive rise in plasma vasopressin with increasing serum sodium. During hypertonic saline alone, vasopressin levels began to rise at an increment in serum sodium of 1.67 +/- 0.35 mM in the young and 1.43 +/- 0.32 mM in the elderly and rose linearly with increasing serum sodium. When ANP was infused with hypertonic saline (with peak ANP levels of approximately 1,000 pM), vasopressin levels began to rise at an increment in serum sodium of 4.43 +/- 0.67 mM in the young and 4.57 +/- 0.43 mM in the elderly (P less than 0.01 vs. saline alone). Furthermore, the vasopressin response for any given serum sodium was significantly reduced in both young and elderly subjects, resulting in a rightward displacement of the curve relating vasopressin response to sodium concentration (P less than 0.001). In conclusion, ANP not only suppresses vasopressin but raises the threshold for release of vasopressin in response to osmotic stimulation in both young and elderly individuals. High circulating ANP levels may be responsible in part for the suppression of vasopressin levels and water diuresis seen during states of volume expansion.


1978 ◽  
Vol 44 (6) ◽  
pp. 964-968 ◽  
Author(s):  
B. M. Yergin ◽  
K. Saketkhoo ◽  
E. D. Michaelson ◽  
S. M. Serafini ◽  
K. Kovitz ◽  
...  

Nasal mucous velocity was estimated by following the motion of radiopaque discs of Teflon by means of a fluoroscopic image intensifier. From 5 to 10 discs were deposited on the superior surface of the inferior turbinate with a forceps. No local anesthesia was employed and the subjects experienced no discomfort. The linear velocity of the discs was obtained by playing the videotape onto a television monitor, measuring distance with a ruler, and dividing by elapsed time. Duplicate runs of 1–2 min, 15 min apart were very reproducible but runs at 4-h intervals or daily over a 5-day period had a coefficient of variation of 30%. Average nasal velocity for individual ranged from 0 to 22.5 mm/min and group means ranged from 6. 8 to 10.8 mm/min. There was no statistically significant difference in nasal mucous velocity between young and elderly subjects nor was there a sexual difference. The saccharin test of nasal mucous transport was unsatisfactory because of inability to repeat the test more often than 1–2 h and its propensity to produce mild discomfort in a significant number of subjects. Saccharin times did not correlate significantly with values of nasal mucous velocity.


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