scholarly journals Revisiting the role of a service-Day Hospital in infectious diseases, based on the natural history of HIV infection in the era of potent antiretroviral combination therapy

2010 ◽  
Vol 11 (1) ◽  
pp. 47-49
Author(s):  
Roberto Manfredi
Keyword(s):  
Health Care ◽  
Natural History ◽  
Combination Therapy ◽  
Infectious Diseases ◽  
Metropolitan Area ◽  
Outpatient Service ◽  
Day Hospital ◽  
History Of ◽  
Care Assistance

On the ground of the analysis of health care assistance performed by an Infectious Diseases Day-Hospital outpatient service operating in a metropolitan area during a 15-year-old time, we assess the evolution of referred disorders, in order to plan eventual future remodeling of the service and structure organization and performances, based one the present and evolving epidemiology of infectious diseases.

scholarly journals Natural History of Excessive Daytime Sleepiness: Role of Obesity, Weight Loss, Depression, and Sleep Propensity

SLEEP ◽  
2015 ◽  
Vol 38 (3) ◽  
pp. 351-360 ◽  
Author(s):  
Julio Fernandez-Mendoza ◽  
Alexandros N. Vgontzas ◽  
Ilia Kritikou ◽  
Susan L. Calhoun ◽  
Duanping Liao ◽  
...  
Keyword(s):  
Weight Loss ◽  
Natural History ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
History Of ◽  
Sleep Propensity

The natural history of sleep disturbance among OEF/OIF veterans with TBI and PTSD and the role of proxy variables in its measurement

2017 ◽  
Vol 96 ◽  
pp. 60-66 ◽  
Author(s):  
Paul R. King ◽  
Kerry T. Donnelly ◽  
Gary Warner ◽  
Michael Wade ◽  
Wilfred R. Pigeon
Keyword(s):  
Natural History ◽  
Sleep Disturbance ◽  
Proxy Variables ◽  
History Of

scholarly journals Role of Endothelial Shear Stress in the Natural History of Coronary Atherosclerosis and Vascular Remodeling

2007 ◽  
Vol 49 (25) ◽  
pp. 2379-2393 ◽  
Author(s):  
Yiannis S. Chatzizisis ◽  
Ahmet Umit Coskun ◽  
Michael Jonas ◽  
Elazer R. Edelman ◽  
Charles L. Feldman ◽  
...  
Keyword(s):  
Shear Stress ◽  
Natural History ◽  
Vascular Remodeling ◽  
Coronary Atherosclerosis ◽  
History Of ◽  
Endothelial Shear Stress

Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice

2015 ◽  
Vol 93 (8) ◽  
pp. 641-648 ◽  
Author(s):  
Azza Ramadan ◽  
Mark D. Wheatcroft ◽  
Adrian Quan ◽  
Krishna K. Singh ◽  
Fina Lovren ◽  
...  
Keyword(s):  
Natural History ◽  
Thrombus Formation ◽  
Aortic Aneurysms ◽  
Ang Ii ◽  
Abdominal Aortic ◽  
Suprarenal Aorta ◽  
History Of ◽  
Categorical Distribution

Autophagy regulates cellular homeostasis and integrates the cellular pro-survival machinery. We investigated the role of autophagy in the natural history of murine abdominal aortic aneurysms (AAA). ApoE−/− mice were implanted with saline- or angiotensin II (Ang-II)-filled miniosmotic pumps then treated with either the autophagy inhibitor chloroquine (CQ; 50 mg·(kg body mass)–1·day–1, by intraperitoneal injection) or saline. Ang-II-elicited aneurysmal expansion of the suprarenal aorta coupled with thrombus formation were apparent 8 weeks later. CQ had no impact on the incidence (50% for Ang-II compared with 46.2% for Ang-II + CQ; P = NS) and categorical distribution of aneurysms. The markedly reduced survival rate observed with Ang-II (57.1% for Ang-II compared with 100% for saline; P < 0.05) was unaffected by CQ (61.5% for Ang-II + CQ; P = NS compared with Ang-II). CQ did not affect the mean maximum suprarenal aortic diameter (1.91 ± 0.19 mm for Ang-II compared with 1.97 ± 0.21 mm for Ang-II + CQ; P = NS). Elastin fragmentation, collagen accumulation, and smooth muscle attrition, which were higher in Ang-II-treated mice, were unaffected by CQ treatment. Long-term CQ administration does not affect the natural history and prognosis of experimental AAA, suggesting that global loss of autophagy is unlikely to be a causal factor in the development of aortic aneurysms. Manipulation of autophagy as a mechanism to reduce AAA may need re-evaluation.

Clinician Advocacy and Intersex Health: A History of Intersex Health Care and the Role of the Clinician Advocate Past, Present, and Future

2021 ◽  
Vol 50 (9) ◽  
Author(s):  
Gnendy Indig ◽  
Mariana Serrano ◽  
Katharine B. Dalke ◽  
Nwadiogo I. Ejiogu ◽  
Frances Grimstad
Keyword(s):  
Health Care ◽  
History Of

scholarly journals Emerging infectious disease preparedness and response in healthcare: perspectives from COVID-19 and the role of College-Learnt Microbiology

2021 ◽  
Vol 22 (3) ◽  
pp. 312-321
Author(s):  
J. Tonui ◽  
W. Chepkutto ◽  
J. Rotich
Keyword(s):  
Health Care ◽  
Infectious Diseases ◽  
Health Care Providers ◽  
Healthcare Providers ◽  
Emerging Infectious Diseases ◽  
Microbial Pathogens ◽  
Infection Prevention And Control ◽  
Care Providers ◽  
Emerging Infections

Coronavirus disease 2019 (COVID-19) pandemic began in December 2019 in Wuhan City China where it is believed to have been transmitted to humans from an unknown animal species. The public health, social and economic impact of the pandemic world over is detrimental. Health care providers at the frontline in the fight against COVID-19 are at the greatest risk of infection and so far, many have been infected and some have already died from the disease. Thus, it is imperative that healthcare providers have adequate knowledge of infectious diseases and microbial pathogens to comprehend the scale of risk for better recognition and response. Microbiological concepts of infection prevention and control, hand hygiene and aseptic techniques are essential in slowing down the spread of the virus. COVID-19 has proven that infectious agents can emerge from any region in the world and can spread rapidly with ominous consequences to all humanity. This narrative review discusses the role of college-learnt microbiology in health care provider preparedness for emerging infectious diseases in light of the current pandemic. Keywords: Emerging; Infections; Preparedness; Response; Microbiology; COVID-19; Training

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