scholarly journals The predictive value of mean platelet volume, neutrophil lymphocyte ratio and platelet lymphocyte ratio in acute middle cerebral artery infarction patients

2020 ◽  
Author(s):  
Hamit ÇELİK ◽  
Mesut ERBAS
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Predictive Value ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Middle Cerebral Artery Infarction ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio

scholarly journals Profile of mean platelet volume, neutrophil - lymphocyte ratio and platelet - lymphocyte ratio in patient with psoriasis

2021 ◽  
Vol 7 (6) ◽  
pp. 765
Author(s):  
Fatema Khatun ◽  
Zakir Ahmed ◽  
Harasit K. Paul ◽  
Zinat Amin ◽  
M. S. Z. Chowdhury
Keyword(s):  
Mean Platelet Volume ◽  
Inflammatory Diseases ◽  
Systemic Disease ◽  
Severity Index ◽  
Response To Therapy ◽  
Platelet Volume ◽  
Psoriasis Area Severity Index ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Platelet Lymphocyte Ratio

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic, inflammatory, systemic disease. In response to therapy in psoriasis patients, the psoriasis area severity index (PASI) is used to evaluate the disease activity. However more objective laboratory tools should be developed besides PASI. In various inflammatory diseases, mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR), and platelet lymphocyte ratio (PLR) are inflammatory biomarkers that are known to be evaluated. The aim of the study was to assess the frequency of platelet activation and leukocyte infiltration by measuring MPV, NLR, and PLR.</p><p class="abstract"><strong>Methods:</strong> This was a case-control observational study conducted at department of dermatology and venereology at Bangabandhu Sheikh Mujib Medical University from July 2016 to December 2017. A total of 55 psoriasis cases and 55 healthy controls were included according to inclusion and exclusion criteria.<strong></strong></p><p class="abstract"><strong>Results:</strong> We have investigated a total of 55 psoriasis patients and another 55 age-sex matched control. There were 31 males (56.36%) and 24 females (43.44%) psoriasis patients in the study. The mean age of the patient was 34.27±13.44 years. Mean±standard deviation (SD) value of MPV, NLR, and PLR in our study cases were 9.92±1.21, 4.32±8.53, and 292.96±88.80 whereas in the case of control values were 9.46±0.636, 4.54±8.51, and 162.26±103.38 respectively.</p><p class="abstract"><strong>Conclusions:</strong> In conclusion, we suggest MPV is a strong indicator of psoriasis severity. MPV and PLR should be followed up routinely to take preventive measures against psoriasis-related micro and macro vascular thrombotic complications.</p>

scholarly journals Evaluation of Neutrophil, Lymphocyte, Platelet, Mean Platelet Volume, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio in Prostate Cancer Patients Treated with Radiotherapy

2020 ◽  
Vol 7 (5) ◽  
pp. 482-488 ◽  
Author(s):  
Nurten Bahtiyar ◽  
Özlem Mermut
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Mean Platelet Volume ◽  
Venous Blood ◽  
Control Group ◽  
Platelet Volume ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Radiotherapy Group ◽  
Platelet Lymphocyte Ratio

Objective: Radiotherapy is a one cura­tive method for prostate cancer. Ionizing radiation can cause inflammation of tissues in and around the irradiated sites. But it is also suggested that low-dose radiation has anti-inflammatory effects. The present study was aimed at investigating the effects of radiotherapy on some inflammatory markers in prostate cancer patients. Material and Methods: A total of 42 patients with prostate cancer and 30 healthy subjects were included in the present study. The day prior to radiotherapy (pre radiotherapy group) and the day radiotherapy was completed (post radiotherapy group) venous blood samples were collected. Neutrophil, lymphocyte, platelet, mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) levels were detected. Results: Neutrophil values of the pre radiotherapy group were higher than the control group (p<0.05), and values of the post radiotherapy group were lower than the pre radiotherapy group (p<0.001). Lymphocyte values of the post radiotherapy group were lower than the control, and the pre radiotherapy groups (p <0.001 for both). Platelet values were decreased in the post radiotherapy group compared to the pre radiotherapy group (p <0.01). MPV values of the pre radiotherapy group were higher than the control group (p<0.05), and were lower in the post radiotherapy group than the pre radiotherapy group (p <0.001). NLR and PLR values were decreased in the post radiotherapy group compared to the control group (p <0.001 for both), and were increased in post radiotherapy group compared to the pre radiotherapy group (p<0.001 for both). Conclusion: Our findings showed that neutrophil, and MPV were increased in the pre radiotherapy group compared to the control group. Neutrophil, lymphocyte, platelet, and MPV were decreased, NLR and PLR were increased in the post radiotherapy group compared to the pre radiotherapy group.

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