scholarly journals Neuroimagerie fonctionnelle chez l’adolescent avec un trouble de personnalité limite

2016 ◽  
Vol 41 (1) ◽  
pp. 141-162 ◽  
Author(s):  
Amélie LeBoeuf ◽  
Jean-Marc Guilé ◽  
Réal Labelle ◽  
David Luck
Keyword(s):  
Affective Disorders ◽  
Diagnostic Interview ◽  
School Age Children ◽  
School Age

De nombreuses études en neuroimagerie fonctionnelle (IRMf) menées chez les adultes présentant un trouble de personnalité limite (TPL) convergent pour identifier un patron d’activation neuronale, notamment fronto-limbique, différent de celui activé chez les adultes sans TPL lors des tâches de visualisation d’images émotionnelles. À ce jour, aucune étude en IRMf n’a été réalisée chez les adolescents avec TPL. Ce projet pilote vise à évaluer la faisabilité d’un protocole d’IRMf chez des adolescentes avec TPL et à identifier les régions neuronales d’intérêt pour les études de neuroimagerie chez cette population. Le projet porte sur six adolescentes euthymiques présentant un diagnostic de TPL (âge moyen : 15,8 ± 0,9 ans) et six adolescentes témoins sans diagnostic psychiatrique (âge moyen : 15,5 ± 1,2 ans). Après l’évaluation diagnostique incluant le Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime et le Diagnostic Interview for Borderline – Revised version, les participantes ont complété une tâche d’IRMf au cours de laquelle elles devaient regarder 20 images à valence affective positive, 20 images à valence affective négative et 20 images neutres. L’étude de faisabilité montre que les participantes ont été recrutées en 22 mois et que le protocole était bien toléré par celles-ci. Les résultats montrent que le visionnement des scènes positives et négatives a entraîné une plus grande activation de plusieurs aires limbiques ainsi que frontales, temporales et du cervelet chez le groupe TPL. Les aires limbiques et préfrontales semblent être des régions d’intérêt dans l’étude du fonctionnement neuronal chez les adolescentes avec TPL.

6.73 PSYCHOMETRIC PROPERTIES OF THE DSM-5 SCHEDULE FOR AFFECTIVE DISORDERS AND SCHIZOPHRENIA FOR SCHOOL-AGE CHILDREN-PRESENT AND LIFETIME VERSION

2019 ◽  
Vol 58 (10) ◽  
pp. S295
Author(s):  
Gudmundur A. Skarphedinsson ◽  
Orri Smarason ◽  
Harpa Hronn Hardardottir ◽  
Olafur Thordarson ◽  
Fridrik Mar Aevarsson ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
Affective Disorders ◽  
School Age Children ◽  
School Age ◽  
Dsm 5

Validity of K-SADS-PL (Schedule for Affective Disorders and Schizophrenia for School-Age Children—Present and Lifetime Version) depression diagnoses in an adolescent clinical population

2010 ◽  
Vol 64 (6) ◽  
pp. 409-420 ◽  
Author(s):  
Bertrand Lauth ◽  
Guðmundur B. Arnkelsson ◽  
Páll Magnússon ◽  
Guðmundur Á. Skarphéðinsson ◽  
Pierre Ferrari ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Clinical Population ◽  
School Age Children ◽  
School Age

Schedule for Affective Disorders and Schizophrenia for School Age Children--Present and Lifetime Version; Spanish Version

2018 ◽  
Author(s):  
Francisco R. de la Peña ◽  
Lino R. Villavicencio ◽  
Juan D. Palacio ◽  
Fernando J. Félix ◽  
Marcela Larraguibel ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Spanish Version ◽  
School Age Children ◽  
School Age

scholarly journals Interrater agreement for the schedule for affective disorders and schizophrenia epidemiological version for school-age children (K-SADS-E)

2003 ◽  
Vol 25 (2) ◽  
pp. 87-90 ◽  
Author(s):  
Guilherme V Polanczyk ◽  
Mariana Eizirik ◽  
Victor Aranovich ◽  
Daniel Denardin ◽  
Tatiana L da Silva ◽  
...  
Keyword(s):  
Disruptive Behavior ◽  
Affective Disorders ◽  
Brazilian Portuguese ◽  
Kappa Coefficient ◽  
Interrater Agreement ◽  
School Age Children ◽  
Childhood And Adolescence ◽  
School Age ◽  
Porto Alegre ◽  
Attention Deficit Hyperactivity Disorders

OBJETIVE: The main objective of this study was to assess the interrater agreement for the Schedule for Affective Disorders and Schizophrenia Epidemiological version for School-Age Children (K-SADS-E). METHODS: Four interviewers being trained with the K-SADS-E scored independently 29 videotaped interviews performed with psychiatric outpatients in the ADHD Outpatient Clinic at Hospital de Clínicas de Porto Alegre. Interrater agreement analysis was performed using the kappa coefficient (k). RESULTS: Kappa coefficients were .93 (p<.001) for affective disorders, .9 (p<.001) for anxiety disorders, .94 (p<.001) for attention-deficit/hyperactivity disorders and disruptive behavior disorders. CONCLUSION: These findings suggest an excellent interrater agreement for the diagnosis of several mental disorders in childhood and adolescence by the Brazilian Portuguese version of the K-SADS-E.

P01-364 Associations of 5HTT-LPR with ADHD symptoms are moderated by platelet MAOB activity

2011 ◽  
Vol 26 (S2) ◽  
pp. 366-366
Author(s):  
H.-L. Wargelius ◽  
K. Malmberg ◽  
J.-O. Larsson ◽  
L. Oreland
Keyword(s):  
Enzyme Activity ◽  
Behavior Problems ◽  
Disruptive Behavior ◽  
Affective Disorders ◽  
Clinical Sample ◽  
School Age Children ◽  
Study Group ◽  
School Age ◽  
Adhd Symptoms ◽  
Psychiatric Problems

IntroductionThe monoamine systems have been suggested to play a role for the biological background of ADHD symptoms. Thus, polymorphisms in e.g. the serotonin transporter (5HTT) gene have been associated with ADHD like phenotypes.Furthermore, platelet MAOB activity has frequently been linked to impulsiveness-related traits.ObjectiveBiological markers and candidate genes for psychiatric problems are often studied separately. We study ADHD symptoms with regard to the combination of platelet MAOB activity and 5HTT genotype.AimTo test the hypothesis that associations between ADHD like behavior problems and 5HTT-LPR polymorphism, would be more robust if calculations were done in combination with platelet MAOB enzyme activity.MethodsThe study group consisted of 156 adolescent twin pairs, i.e. 312 individuals. ADHD symptoms were scored with a structured clinical interview of both the twin and a parent using Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL).ResultsPresence of a short 5HTT-LPR allele, in combination with high levels of platelet MAOB enzyme activity was associated with higher scores of ADHD like problems and disruptive behavior in boys. No such associations were found in girls.ConclusionThis examination of ADHD scores in a non-clinical sample suggests that the effects of the 5HTT-LPR are moderated by platelet MAOB activity.

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