scholarly journals Peer Review #3 of "One-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditions (v0.1)"

2018 ◽  
Keyword(s):  
Peer Review ◽  
Heterogeneous Catalyst ◽  
Mannich Reaction ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions

scholarly journals One-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditions

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5065 ◽  
Author(s):  
Giovanna Bosica ◽  
Ramon Zammit
Keyword(s):  
Heterogeneous Catalyst ◽  
Mannich Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Free Medium ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Activity Loss ◽  
A Minor ◽  
Minor Activity

An environmentally-friendly, one-pot multicomponent reaction of various aldehydes, amines and nitroalkanes for the synthesis of β-nitroamines is here described. Amberlyst A-21 supported CuI was found to be a highly efficient novel heterogeneous catalyst for the three-component nitro-Mannich reaction between aldehydes, amines and nitroalkanes. The developed protocol is performed in a solvent-free medium to produce a variety of β-nitroamines in good to excellent yields within short reaction times. The catalyst can be easily prepared and recovered. It has been tested up to eight times with only a minor activity loss.

scholarly journals Synthesis of 2,4,6-triarylpyridines Using AlPO4 Under Solvent-free Conditions

2010 ◽  
Vol 2 (2) ◽  
pp. 337-342 ◽  
Author(s):  
P. Rajput ◽  
N. J. P. Subhashini ◽  
Shiva Raj
Keyword(s):  
Heterogeneous Catalyst ◽  
Simple Procedure ◽  
Reaction Times ◽  
Aluminum Phosphate ◽  
Solvent Free ◽  
One Pot ◽  
One Pot Synthesis ◽  
Solvent Free Conditions

A series of 2,4,6-triarylpyridines have been prepared using a variety of aromatic and heteroaromatic aldehydes in the presence of aluminum phosphate (AlPO4) as a heterogeneous catalyst at 120 oC under solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure, shorter reaction times, milder conditions and the catalyst exhibited remarkable reusable activity. Keywords: Aluminum phosphate; 2,4,6-triarylpyridines; One-pot synthesis; Shorter reaction times;  Reusable activity.  © 2010 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v2i2.3859               J. Sci. Res. 2 (2), 337-342 (2010) 

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