Morphometric Analysis based on length of Cervical enlargement of spinal cord with the gestational age in Indian Human foetuses

Background: Thyroid gland is one of the organs of interest for researchers since a long time. Though, detailed study about adult thyroid gland is there in the literature but thyroid gland at different stages in the foetal period is far less available.Aims and Objective: To find out the morphological and morphometric features on the development of foetal thyroid gland in relation with different gestational weeks.Materials and Methods: The study was carried in the Department of Anatomy, Manipal College of Medical Sciences, Pokhara, Nepal, on 40 human foetuses of known gestational age. The midline dissection of the neck was done to expose the thyroid gland. The shape and measurements like length, breadth and thickness of both lobe of the gland were noted.Results: The mean values of all parameters by gestational age were calculated. In the present study, the weight of foetuses showed gradual increase from 10th week to 38th weeks of gestation. In the normally developing foetuses the thyroid gland dimension and its weight also increases with increase gestational age.Conclusion: There was no more difference between the dimension of right and left lobe of thyroid gland. The study provides morphological and morphometric knowledge on the development of foetal thyroid gland from 10th week to 38th weeks of gestation. The knowledge of thyroid gland weight and dimension and body weight in relation to the gestational age might be helpful to judge the thyroid structure in preterm babies.Asian Journal of Medical Sciences Vol.9(6) 2018 40-44

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Peripheral and brain tissue catecholamine content in intact and anti-NGF-treated fetal sheep

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1987.252.1.r7 ◽

1987 ◽

Vol 252 (1) ◽

pp. R7-R12 ◽

Cited By ~ 2

Author(s):

J. A. Schuijers ◽

D. W. Walker ◽

C. A. Browne ◽

G. D. Thorburn

Keyword(s):

Spinal Cord ◽

Central Nervous System ◽

Nervous System ◽

Gestational Age ◽

Adrenal Glands ◽

Matched Control ◽

Cervical Spinal Cord ◽

Fetal Sheep ◽

Catecholamine Content ◽

The Central Nervous System

Fetal lambs were treated with a single dose of anti-mouse nerve growth factor (anti-NGF) at 80 days gestational age. The catecholamine content of tissues was determined at 135 days gestational age. There was a reduction of either norepinephrine, epinephrine, or both, in the thymus, thyroid, atrium (but not ventricle), lung, liver, kidney, and jejunum when compared with age-matched control fetuses. The spleen, ileum, colon, and the adrenal glands were not affected by anti-NGF. In treated fetuses there was a reduction in catecholamine content of the thalamus, hypothalamus, hippocampus, medulla, cerebellum, and cervical spinal cord. These results show that some tissues are sensitive to, and some are refractory to, the action of anti-NGF at 80 days gestation. Also the results suggest that NGF may play a role in the development of catecholamine-containing neurons within the central nervous system.

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