Primary Squamous Cell Carcinoma of the Distal Hallux

2013 ◽  
Vol 103 (2) ◽  
pp. 149-151 ◽  
Author(s):  
Michael G. David ◽  
Jennifer Stumph ◽  
Brianna M. David

Squamous cell carcinoma is a common disease of cutaneous tissue with a great ability to form metastases. Squamous cell carcinoma is found most commonly on sun-damaged skin and has a rare occurrence on the toes and feet. The patient was a 68-year-old woman who was seen at a podiatric specialty office with a complaint of pain in her left great toe and toenail. Radiographs displayed erosion of the distal hallux, and magnetic resonance imaging revealed no further spread of disease in the proximal phalanx. An amputation was performed of the hallux interphalangeal joint, and pathology confirmed squamous cell carcinoma of the verrucous type. (J Am Podiatr Med Assoc 103(2): 149–151, 2013)

2016 ◽  
Vol 9 ◽  
pp. CGast.S40605 ◽  
Author(s):  
Nikhil Sonthalia ◽  
Samit S. Jain ◽  
Ravindra G. Surude ◽  
Vinay B. Pawar ◽  
Suhas Udgirkar ◽  
...  

Esophageal squamous cell carcinoma (ESCC) is the commonest primary malignant esophageal tumor, which typically presents as endoscopically visible surface mucosal ulcerations, irregularities, or polyploidal masses. We here report a rare case of primary ESCC with completely intramural growth under a normal looking intact nondysplastic surface squamous epithelium disguising as a submucosal tumor. Upper gastrointestinal endoscopy-guided mucosal biopsy was negative for malignancy. Endoscopic ultrasound (EUS) revealed a heteroechoic solid mass originating from the muscularis propria of the distal esophagus. Cytological study of EUS-guided fine needle aspiration from the mass was suggestive of squamous cell carcinoma, which was confirmed on immunohistochemistry. There was no evidence of metastatic origin of this tumor or continuous cancer involvement from the surrounding structures, including the head, neck, and lungs on bronchoscopy, computed tomography scan, and positron emission tomography scan. Exclusive intramural squamous cell carcinoma with normal overlying mucosa is an exceedingly rare presentation of primary ESCC with only four cases reported in the literature so far. A high index of suspicion is required by the gastroenterologists and pathologists in diagnosing these cases as these tumors closely mimic the mesenchymal submucosal tumors such as lipoma, leiomyoma, and gastrointestinal stromal tumors. EUS is an indispensable tool in making a preoperative diagnosis and therapeutic decision making.


2005 ◽  
Vol 91 (5) ◽  
pp. 418-420 ◽  
Author(s):  
Gabriella Guerriero ◽  
Maria Giovanna Zagami ◽  
Marilena Montesano ◽  
Angelo Primavera ◽  
Rita Carino ◽  
...  

Squamous cell breast carcinoma is a rare occurrence. Often the tumor is metastatic from an extramammary primary tumor. In order to determine the nature of the lesion, extensive sampling is necessary. We report a case of primary squamous cell carcinoma of the breast diagnosed by vacuum-assisted core biopsy.


Oral Oncology ◽  
2015 ◽  
Vol 51 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Arun Khattri ◽  
Zhixiang Zuo ◽  
Johannes Brägelmann ◽  
Michaela K. Keck ◽  
Mohamed El Dinali ◽  
...  

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