Os Intermetatarseum and Polymetatarsia Without Polydactyly: A Case Report

2020 ◽  
Vol 110 (5) ◽  
Author(s):  
Michelle Kavin ◽  
Nicholas Taweel ◽  
Paul Sullivan ◽  
Charles Langman

Nontraumatic bony abnormalities of the foot occur at different rates, according to the literature. However, it is uncommon to see rare variations presenting together in one patient. This article discusses two less common anomalies: fused os intermetatarseum and polymetatarsia without polydactyly. Etiology, symptomology, diagnosis, and treatment are reviewed, in addition to the relationship of the two conditions to each other. We then discuss a case where both anomalies are present at the same time in a 17-year-old patient.


2014 ◽  
Vol 86 (9) ◽  
Author(s):  
Łukasz Ulatowski ◽  
Anna Kaniewska

AbstractThe study presented a case of a patient with a neurilemoma of the median nerve. It presented as a six centemeters tumor, at the level of the proximal one third of the arm with only mild paraesthesias within frst to third ray of the hand. MRI showed the relationship of the tumor and the median nerve, and allowed for the preliminary diagnose of a benign peripheral neural sheath tumor (neurilemoma or neurofibroma). During the first operation the tumor has not been excised, because nerve reconstruction technique was not available. During the second procedure excision of the tumor has been performed without resection of the median nerve trunk with no postoperative deficiencies. The paper provides a detailed description of a surgical procedure. The presented case, like current publications shows that peripheral neural sheath tumor may be usually excised without resection of the nerve trunk, although the possibility of nerve fascicles injury or the need to excise them in the case of neurofibroma clearly suggest that these type of operations should be carried out in centers with microsurgical facilities.



Author(s):  
Tevfik Kalelioglu ◽  
Guler Celikel ◽  
Ozlem Devrim Balaban ◽  
Nesrin Karamustafalioglu ◽  
Jennifer Kim Penberthy

Objective: Neuroleptic malignant syndrome (NMS) is a rare but severe side effect of antipsychotic medication. Neutrophil-lymphocyte ratio (NLR) is a simple marker used to measure systemic inflammation. Method: In this case report we explore the relationship of inflammation in the etiology of NMS. In our case involving NMS, although there was no leukocytosis, the NLR was increased up to systemic infection levels. Conclusion: We hypothesized that systemic inflammation may take a role in developing NMS. If so, NLR could be a new marker of NMS that may be able to provide more sensitive results than leukocyte levels.



PEDIATRICS ◽  
1954 ◽  
Vol 14 (5) ◽  
pp. 547-556
Author(s):  
ALBERT J. SOLNIT ◽  
MILTON J. E. SENN

1. The out-patient clinic is the most valuable place for the physician to learn how comprehensive pediatrics can be mastered in his every-day office and home-visit practice. It is also the logical place to teach the relationship of community resources to pediatric practice. 2. Comprehensive medical care of the child is defined as the prevention and treatment of physical disease, and the supervision of healthy growth and development, physical and psychological. Through his comprehension of physical, psychological and social forces that influence the child, the pediatrician enables the child and his family to take an active role in solving their health problem. 3. The interview should serve as a basic instrument of diagnosis and treatment. It should be flexible, and enable the patient to express fears, anticipations and questions about his symptoms. It should be practical in length of time and sequence, depending on the patient's symptoms and his reactions to being examined by the doctor. 4. The attitudes necessary for the practice of pediatrics are best acquired by the student through the demonstrations of his teachers and through his professional identification with them. 5. When pediatric teaching is focussed on the patient as a person, a student learns that: a) Every patient is an interesting person. It can be as satisfying and important to care for a six-week-old infant who is well or a child who is going to camp, as one who suffers from a rare disease. b) There is no such thing as a non-contributory family history. It is necessary to know the meaning that complaints or questions have for the mother and the child. This can only be obtained through the physician's expressed interest in both, and in his patient attitude and willingness to listen to what both have to tell him. c) The physician is faced with a patient (child) who is extremely dependent on parents or parental figures. The parents and child form a unit. It is the pediatrician's goal to help improve the health of the child by understanding the child's position in the unit. He should utilize the assets of this unit for the child and parents. d) His interest in and acceptance of the patient results in more effective diagnosis and treatment. This attitude develops gradually when adequate supervision is available.



2017 ◽  
Vol 1 (2) ◽  
pp. 95
Author(s):  
Timothy Nyckowski ◽  
Roger Ceilley ◽  
Joshua Wilson

Introduction: Sarcoidosis is a systemic granulomatous inflammatory disease with an unknown etiology and complex pathogenesis. Existing literature supports the relationship of new-onset sarcoidosis with the use of a several biologic agents. Since the skin is the second most commonly involved organ in sarcoidosis and often precedes systemic involvement, dermatologists must be able to recognize its non-specific clinical presentation.Case Report: We present a 45 year old female with psoriatic arthritis who developed biopsy proven cutaneous sarcoidal granulomas with pulmonary involvement shortly after initiating secukinumab for treatment of psoriatic arthritis. Despite discontinuation of secukinumab, the sarcoidosis has persisted.Discussion: This is the first case report of secukinumab, or any IL-17 inhibitor related sarcoidosis that we are aware of in the literature. Dermatologists should be aware of this as a possible side effect of secukinumab use. As the research on the role of IL-17 in the pathogenesis of sarcoidosis continues to develop, the implications of this side effect of IL-17 inhibition may have important future implications.



2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Panagiota Spyridonos ◽  
Vasiliki Zampeli ◽  
Sophia-Nefeli Rapti ◽  
Ioannis D. Bassukas

Induction of new psoriasis sites was reported in only a small amount of psoriasis patients undergoing tattooing, despite the intuitive belief that tattoo trauma might awaken the disease due to the isomorphic phenomenon of Koebner. In this case report, we discuss a patient who presented with a remarkable sparing of his three tattoo sites during a guttate psoriasis flare-up that was unrelated to tattooing. The spatial concordance of tattoo and psoriasis lesions was analyzed on clinical pictures of tattoo sites taken during the psoriasis episode. For the quantification of the spatial distribution of the psoriasis lesions, Voronoi diagrams were generated, and coefficients of variation and the two-sample t-test were employed to compare the distributions of Voronoi patch sizes in different settings. Compared to skin areas without tattoos, a tattoo introduced a higher variation in the sizes of the Voronoi patches centered around psoriasis lesions. Based on our findings, we would like to discuss the possible role of macrophages as the key cellular link in the complex pathophysiologic relationship between tattooing/tattoo and psoriasis. Taking into account the relationship of autophagy and psoriasis lesions, we propose the hypothesis that tattoos represent a “psoriasis-hostile” tissue environment pertained by a population of LAP active M2-polarized macrophages. Further clinical studies of the relationship of psoriasis lesions to the tattooed skin are needed and may provide important insights into the role of macrophages in the pathogenesis of psoriasis.



Author(s):  
G. Chuprina ◽  
T. Parnikoza ◽  
N. Svyrydova

The theory of the five elements is widely used in traditional Chinese medicine, and the division of natural phenomena according to the properties of the five elements and the nature of the relationship between them, is practical in clinical acupuncture: to characterize the structural, physiological and pathological features of the patient, diagnosis and treatment. With the development of diseases there is a pathological relationship between Zhang-Fu organs and tissues that they are subordinated to. The human body is an organic whole, in which there are numerous interconnections in the development of the pathological process due to the existing modified interconnections. It is established that the theory of five elements is a simple theory with certain limitations. The laws of the relationship between the elements of the U-Syin cycle are not a reflection of all possible interconnections between the Zhang-Fu organs and the related tissues. In clinical practice, these laws show objective physiological and pathological communications between the internal organs and can be used in the process of acupuncture diagnosis and treatment. The theory of the five elements lies at the heart of the methodology of traditional acupuncture diagnostics, used during its implementation and data analysis, it determines the pathological states in accordance with the characteristics and laws of the relationship of the five elements and formulates the syndromic diagnosis of traditional Chinese Medicine (TCM).



1981 ◽  
Vol 46 (1) ◽  
pp. 34-38 ◽  
Author(s):  
Leonard L. Lapointe ◽  
Jennifer Horner

Palilalia is an acquired speech disorder characterized by reiteration of utterances in a context of increasing rate and decreasing loudness. The condition has been associated with bilateral subcortical neuropathology. The relationship of palilalia to other adult disfluency syndromes, aphasia, and motor speech disorders requires a thorough understanding of the nature of palilalic case report systematically describes seven distinct types of reiteration, frequency (severity) of reiteration relative to seven types of speech tasks, and consistency and adaptation effects observed in a 29-year-old male.



Sign in / Sign up

Export Citation Format

Share Document