Immunity of breast cancer patients compromised months after chemotherapy treatment

2016 ◽  
Vol 30 (26) ◽  
pp. 14-14
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment

Cognitive decline as a result of impaired sleep and glucose levels during chemotherapy treatment in breast cancer patients.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e20713-e20713
Author(s):  
Liliana Moyers-Ruiz ◽  
Tamas Hickish ◽  
Andrew Mayers ◽  
Simon Thompson
Keyword(s):  
Breast Cancer ◽  
Cognitive Decline ◽  
Cancer Patients ◽  
Qualitative Interview ◽  
Sleep Efficiency ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Chemotherapy Group ◽  
Glucose Levels ◽  
Self Reports

e20713 Background: Sleep efficiency might be altered during chemotherapy treatment. Cognitive decline has been associated with sleep disruption, impaired glucose levels, and chemotherapy treatment. We hypothesize that the biological factors considered in this study are playing an important role. Anecdotical reports have shown discrepancy with neuropsychological batteries results, therefore a qualitative interview and memory self-reports will be conducted for the cancer group. Methods: A sample of 32 Breast cancer patients and 29 healthy controls has been recruited in the Dorset area in the UK. The chemotherapy group will be tested three times within de course of their treatment (baseline, mid-treatment, after treatment). The radiotherapy participants will be tested three times within a period of four months, and the healthy control group two times within a four-month period. A subset of chemotherapy participants will be tested six months after chemotherapy. A neuropsychological battery is being used to assess cognitive function, and sleep efficiency is analysed using a sleep monitor and validated self-reports; Furthermore, glucose levels will be analysed for the chemotherapy group, and an online semi-qualitative interview will be conducted for cancer patients for a thematic analysis, along with a Prospective Memory questionnaire. Results: Preliminary data shows that sleep efficiency is disturbed during the course of chemotherapy, although not statistically significant, there is a trend in decreased sleep efficiency percentage when we compared baseline and mid-chemotherapy assessment The strongest tendency is observed on the PSQI self-report, showing an increase in Global PSQI score . Glucose levels show an increase during mid-treatment, although preliminary analyses show no significant effect. Memory data is still under scrutiny and more data will be reported at the poster presentation, along with assessments for times three and four. Conclusions: The inclusion of a semi-qualitative study will add a very important information to this study when test results are compered with anecdotical and self-reports.

scholarly journals Fatigue dan status nutrisi pada pasien dengan kanker payudara yang menjalani kemoterapi

2020 ◽  
Vol 13 (4) ◽  
pp. 278-283
Author(s):  
Sapti Ayubbana ◽  
Sari Narulita
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Nursing Intervention ◽  
P Value ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Cross Sectional ◽  
Breast Cancer Chemotherapy

Fatigue and nutritional status in patients with breast cancer undergoing chemotherapyBackground: Breast cancer is one type of cancer and is one of the leading causes of death in the world. Cancer patients who receive chemotherapy are at risk of impaired nutritional status due to the disease and its treatment. Chemotherapy treatment can have side effects on the gastrointestinal system such as nausea, vomiting, stomatitis, anorexia, changes in taste. These side effects can cause the patient's nutritional intake to decrease. Cancer and its treatment can cause fatigue complaints.Purpose: to identify the relationship between fatigue and nutritional status in patients with breast cancer patients undergoing chemotherapyMethods: The design of this study was quantitative using a cross sectional approach. The population in this study were patients with breast cancer undergoing chemotherapy. This research was conducted at Dr.H. Abdul Moeloek Hospital of Lampung Province with 42 respondents.Results: Spearman correlation test results found that nutritional status variables have a significant relationship with fatigue (p value = 0.031) with moderate correlation strength (r = 0.471).Conclusion: The nursing intervention on the side effects of chemotherapy treatment which has a positive effect on nutritional conditions in an effort to overcome nutritional disorders and complaints of fatigue in cancer patients.Keywords: Breast Cancer; Chemotherapy; Fatigue; Nutritional StatusPendahuluan: Kanker payudara merupakan salah satu jenis kanker dan menjadi salah satu penyebab kematian di dunia. Pasien kanker yang menerima kemoterapi memiliki resiko gangguan status nutrisi akibat penyakit dan pengobatannya. Pengobatan kemoterapi dapat memberikan efek samping terhadap sistem ganstrointestinal seperti mual, muntah, stomatitis, anoreksia, perubahan rasa. Efek samping tersebut dapat menyebabkan asupan nutrisi pasien dapat mengalami penurunan. Kanker dan pengobatannya dapat menyebabkan keluhan fatigue.Tujuan: Mengetahui adanya hubungan antara status nutrisi terhadap fatigue pada pasien kanker payudara yang menjalani kemoterapi.Metode: Desain penelitian ini adalah kuantitatif dengan menggunakan pendekatan cross sectional . Populasi pada penelitian ini adalah pasien dengan kanker payudara yang menjalani kemoterapi. Penelitian ini dilakukan di RSUD Dr.H. Abdul Moeloek Provinsi Lampung dengan 42 responden.Hasil: Pada uji korelasi spearman didapatkan bahwa variabel status nutrisi mempunyai hubungan yang bermakna dengan fatigue ( p value = 0,031) dengan kekuatan korelasi sedang (r = 0,471).Simpulan: Kesimpulan diperlukan intervensi keperawatan terhadap efek samping pengobatan kemoterapi yang berdapak terhadap kondisi nutrisi dalam upaya mengatasigangguan nutrisi dan keluhan fatigue pada pasien kanker 

Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer.

1998 ◽  
Vol 16 (5) ◽  
pp. 1689-1696 ◽  
Author(s):  
J A Broeckel ◽  
P B Jacobsen ◽  
J Horton ◽  
L Balducci ◽  
G H Lyman
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Psychiatric Disorder ◽  
Sleep Quality ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Severe Fatigue ◽  
History Of ◽  
History Of Cancer

PURPOSE Clinical reports suggest that many breast cancer patients experience persistent fatigue as a long-term side effect of adjuvant chemotherapy treatment. To investigate this issue further, we examined the characteristics and correlates of fatigue in women who had completed adjuvant chemotherapy for breast cancer and in a comparison group of women with no history of cancer. PATIENTS AND METHODS Participants were 61 women with breast cancer who had completed chemotherapy an average of 471 days previously and 59 women with no history of cancer. All participants completed standardized self-report measures of fatigue, sleep quality, menopausal symptoms, and coping and were administered a structured clinical interview to identify current and past psychiatric disorder. RESULTS Compared with women with no history of cancer, former adjuvant chemotherapy patients reported more severe fatigue (P < .01) and worse quality of life because of fatigue (P < .05). More severe fatigue among patients was significantly (P < .05) related to poorer sleep quality, more menopausal symptoms, greater use of catastrophizing as a coping strategy, and current presence of a psychiatric disorder. CONCLUSION These findings support the view that many breast cancer patients experienced heightened fatigue after completion of adjuvant chemotherapy treatment. Results yield a profile of women who are at increased risk for heightened fatigue after chemotherapy and suggest ways to intervene clinically to prevent or reduce fatigue in this patient population.

scholarly journals Effects of Behavioral Activation on the Quality of Life and Emotional State of Lung Cancer and Breast Cancer Patients During Chemotherapy Treatment

2017 ◽  
Vol 43 (2) ◽  
pp. 151-180 ◽  
Author(s):  
Concepción Fernández-Rodríguez ◽  
Erica Villoria-Fernández ◽  
Paula Fernández-García ◽  
Sonia González-Fernández ◽  
Marino Pérez-Álvarez
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Behavioral Activation ◽  
Emotional State ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment

Research suggests that the progressive abandonment of activities in cancer patients are related to depression and worse quality of life. Behavioral activation (BA) encourages subjects to activate their sources of reinforcement and modify the avoidance responses. This study assesses the effectiveness of BA in improving quality of life and preventing emotional disorders during chemotherapy treatment. One sample of lung cancer patients and another of breast cancer patients were randomized into a BA experimental group (E.G.lung/4sess. n = 50; E.G.breast/6sess. n = 33) and a control group (C.G.lung/4sess. n = 40; C.G.breast/6sess. n = 35), respectively. In each session and in follow-ups (3/6/9 months), all participants completed different assessment scales. The results converge to show the effectiveness of BA, encouraging cancer patients to maintain rewarding activities which can activate their sources of day-to-day reinforcement and modify their experience avoidance patterns. BA appears to be a practical intervention which may improve social and role functioning and the emotional state of cancer patients during chemotherapy treatment.

Guideline adherence rates of chemotherapy treatment for breast cancer patients treated in U.S. community oncology practices.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 596-596 ◽  
Author(s):  
K. A. Bergstrom ◽  
Z. Wang ◽  
I. Aksamit ◽  
L. Tuscher ◽  
T. Lam ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Guideline Adherence ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Community Oncology

Prospective and working memory decline as a result of impaired sleep and/or impared blood glucose in breast cancer patients during chemotherapy treatment.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. TPS9148-TPS9148
Author(s):  
Liliana Moyers-Ruiz ◽  
Tamas Hickish ◽  
Simon Thompson
Keyword(s):  
Breast Cancer ◽  
Working Memory ◽  
Blood Glucose ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Memory Decline ◽  
Glucose Levels ◽  
Impaired Sleep ◽  
Chemo Brain

TPS9148 Background: Breast cancer patients might develop impaired sleep patterns during chemotherapy, and impaired cognitive function has been associated with sleep patterns disruption. It has been suggested that sleepiness (sleep tendency) in cancer patients is prevalent and causes distress in the patient’s quality of life, that and their cognitive abilities are also affected. Furthermore, increased blood glucose levels among women undergoing chemotherapy may contrubute to memory deficits in breast cancer patients. It is proposed that Prospective and Working Memory are being affected by the disturbance of these biological factors over the course of chemotherapy. Methods: Ninety participants will be invited to take part in the study. Thirty will be breast cancer patients receiving chemotherapy treatment, thirty breast cancer patients receiving treatment other than chemotheray, and thirty healthy controls. Measures of sleep and sleepiness, will be administered at 4 testing sessions during a 9-month period, along with a neuropsychological battery. Additionally, blood samples will be analysed. Eight of planned 60 cancer patients have been enrolled, and four of them have completed the second testing session. For the assessment of sleep/wake activity, participants will be required to wear a sleeping monitor (sensewear armband) for 7 days. Pupil dilatation to observe sleepiness will be meassured by using a Pupillometry developed at Poole hospital in the UK. Prospective Memory will be assessed using CAMPROMT test to analyse if this is a more sensitive measure for mild cognitive impairment. Discussion: Impairment on variables such as sleep, sleepiness and glucose have not been studied within the context of Chemo-Brain on breast cancer patients.Therefore we want to observe whether impaired sleep and sleepiness, and impaired glucose levels are at the core of Prospective and Working Memory decline in Chemo-Brain patients in order to find a cause-and-effect relationship as a consequence of chemotherapy.

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