scholarly journals Fatigue dan status nutrisi pada pasien dengan kanker payudara yang menjalani kemoterapi

2020 ◽  
Vol 13 (4) ◽  
pp. 278-283
Author(s):  
Sapti Ayubbana ◽  
Sari Narulita

Fatigue and nutritional status in patients with breast cancer undergoing chemotherapyBackground: Breast cancer is one type of cancer and is one of the leading causes of death in the world. Cancer patients who receive chemotherapy are at risk of impaired nutritional status due to the disease and its treatment. Chemotherapy treatment can have side effects on the gastrointestinal system such as nausea, vomiting, stomatitis, anorexia, changes in taste. These side effects can cause the patient's nutritional intake to decrease. Cancer and its treatment can cause fatigue complaints.Purpose: to identify the relationship between fatigue and nutritional status in patients with breast cancer patients undergoing chemotherapyMethods: The design of this study was quantitative using a cross sectional approach. The population in this study were patients with breast cancer undergoing chemotherapy. This research was conducted at Dr.H. Abdul Moeloek Hospital of Lampung Province with 42 respondents.Results: Spearman correlation test results found that nutritional status variables have a significant relationship with fatigue (p value = 0.031) with moderate correlation strength (r = 0.471).Conclusion: The nursing intervention on the side effects of chemotherapy treatment which has a positive effect on nutritional conditions in an effort to overcome nutritional disorders and complaints of fatigue in cancer patients.Keywords: Breast Cancer; Chemotherapy; Fatigue; Nutritional StatusPendahuluan: Kanker payudara merupakan salah satu jenis kanker dan menjadi salah satu penyebab kematian di dunia. Pasien kanker yang menerima kemoterapi memiliki resiko gangguan status nutrisi akibat penyakit dan pengobatannya. Pengobatan kemoterapi dapat memberikan efek samping terhadap sistem ganstrointestinal seperti mual, muntah, stomatitis, anoreksia, perubahan rasa. Efek samping tersebut dapat menyebabkan asupan nutrisi pasien dapat mengalami penurunan. Kanker dan pengobatannya dapat menyebabkan keluhan fatigue.Tujuan: Mengetahui adanya hubungan antara status nutrisi terhadap fatigue pada pasien kanker payudara yang menjalani kemoterapi.Metode: Desain penelitian ini adalah kuantitatif dengan menggunakan pendekatan cross sectional . Populasi pada penelitian ini adalah pasien dengan kanker payudara yang menjalani kemoterapi. Penelitian ini dilakukan di RSUD Dr.H. Abdul Moeloek Provinsi Lampung dengan 42 responden.Hasil: Pada uji korelasi spearman didapatkan bahwa variabel status nutrisi mempunyai hubungan yang bermakna dengan fatigue ( p value = 0,031) dengan kekuatan korelasi sedang (r = 0,471).Simpulan: Kesimpulan diperlukan intervensi keperawatan terhadap efek samping pengobatan kemoterapi yang berdapak terhadap kondisi nutrisi dalam upaya mengatasigangguan nutrisi dan keluhan fatigue pada pasien kanker 

2021 ◽  
Vol 1 (2) ◽  
pp. 36-41
Author(s):  
Angga Dian Prastowo

AbstrakKanker payudara adalah penyebab kematian terbesar pada wanita. Salah satu hal yang penting untuk diperhatikan adalah pada pasien kanker payudara yang menjalani kemoterapi akan mengalami efek samping mual muntah, rambut rontok, nyeri, kehilangan nafsu makan dan lain- lain. Penelitian saat ini bertujuan untuk mengetahui pengaruh konseling terhadap tingkat pemahaman penyakit dan efek samping kemoterapi pasien kanker payudara Penderita kanker payudara perlu mengetahui penyakitnya dengan baik agar kualitas hidupnya dapat tetap terjaga. Edukasi yang dilakukan secara perseorangan maupun kelompok pada penderita tentang efek samping obat kemoterapi sangat diperlukan supaya penderita tidak merasa cemas apabila mengalami efek dari kemoterapi tersebut. Pemberian konseling oleh Apoteker pada pasien kemoterapi kanker payudara sangat penting karena dapat meningkatkan pengetahuan pasien, kepatuhan pasien dalam pengobatannya serta dapat meningkatkan kualitas hidup pasien. Tujuan penelitian ini untuk mengetahui pengaruh pemberian konseling oleh Apoteker terhadap tingkat pemahaman penyakit dan efek samping kemoterapi pada pasien kanker payudara di Unit Kemoterapi Salah Satu Rumkit Pemerintah Di Kota Malang..Penelitian ini merupakan studi kuantitatif dengan desain Pre-Experimental berupa pretest-postes design. Banyaknya sampel yang diambil didasarkan atas waktu yaitu selama satu bulan dan sampel diambil dengan metode consecutive sampling. Hasil penelitian menggunakan uji Wilcoxon menunjukkan terdapat perbedaan nilai sebelum dan sesudah diberikan konseling oleh apoteker terhadap pasien kemoterapi kanker payudara dengan nilai signifikansi sebesar 0,000 (P value< 0,05). Kesimpulan pada penelitian ini adalah pemberian konseling oleh apoteker dapat meningkatkan tingkat pemahaman penyakit dan efek samping dari kemoterapi kanker payudara.Kata kunci : konseling, pemahaman, penyakit kanker payudara, efek samping kemoterapi Abstract Breast cancer is the leading cause of death in women. One important thing to note is that breast cancer patients who undergo chemotherapy experience side effects of nausea and vomiting, hair loss, pain, loss of appetite and others. The current study aims to determine the effect of counseling on the level of understanding of the disease and the side effects of breast cancer chemotherapy patients Breast cancer patients need to know the disease well to the quality of life can be maintained. Education is done individually or in groups to the patient about the side effects of chemotherapy drugs is indispensable so that the patient does not feel anxious when experiencing the effects of chemotherapy. Provision of counseling by pharmacists in patients with breast cancer chemotherapy is very important because it can improve patient knowledge, patient compliance in the treatment and can improve the quality of life of patients. The purpose of this study to determine the effect of counseling by pharmacists to the level of understanding of the disease and the side effects of chemotherapy in breast cancer patients on Chemotherapy Unit One Government Hospital In Malang .. This research is a quantitative study with Pre-Experimental design in the form of a pretestposttest design. The number of samples taken based on the time that is for one month and samples were taken with consecutive sampling method. The results using the Wilcoxon test shows that there are differences in values before and after counseling by pharmacists to patients with breast cancer chemotherapy with a significance value of 0.000 (p value <0.05). Conclusion of this research is the provision of counseling by pharmacists can improve the level of understanding of the disease and the side effects of breast cancerchemotherapy. The results using the Wilcoxon test shows that there are differences in values before and after counseling by pharmacists to patients with breast cancer chemotherapy with a significance value of 0.000 (p value <0.05). Conclusion of this research is the provision of counseling by pharmacists can improve the level of understanding of the disease and the side effects of breast cancer chemotherapy. The results using the Wilcoxon test shows that there are differences in values before and after counseling by pharmacists to patients with breast cancer chemotherapy with a significance value of 0.000 (p value <0.05). Conclusion of this research is the provision of counseling by pharmacists can improve the level of understanding of the disease and the side effects of breast cancer chemotherapy. Keywords : Counseling, understanding, breast cancer, chemotherapy side effects


2020 ◽  
Vol 6 (2) ◽  
pp. 89
Author(s):  
Ariyani Wisudawati Nira ◽  
Mira Triharini ◽  
Aria Aulia Nastiti

Introduction: The management of chemotherapy in breast cancer requires a long time and cause miscellaneous of side effects. High resilience is needed by breast cancer patients to undergo chemotherapy regularly. This study aimed to analyze factors associated with the resilience of breast cancer patients undergoing chemotherapy.Methods: This study design was cross-sectional. From the total population of 122 breast cancer patients, a sample of 100 participants was selected using a purposive sampling technique. The independent variables were hardiness, education level, economic status, side effects of chemotherapy, family support, and anxiety. The dependent variable was resilience. The instruments of this study were Hardiness questionnaire, Chemothraphy-Symptom Assessment Scale (C-SAS), Family Support questionnaire, Zung-Self Rating Anxiety Scale (ZSRAS), and Connor-Davidson Resilience Scale (CD-RISC). The Spearmen’s Rho was used for statistical analysis.Results: Hardiness (p=0.000; r=0.310), Education Level (p=0.000; r=0.416), Economic Status (p=0.000; r=0.369), Side Effects of Chemotherapy (p=0.004; r=-0.283) and Family Support (p=0.000; r=0.579) have relation with the resilience. Anxiety has no relation with the resilience (p=0.23; r=0.121).Conclusion: The side effects management of chemotherapy and family support were necessary to increase the resilience of breast cancer patients undergoing chemotherapy. It is highly recommended to the next researchers to do some studies about factors associated with the side effects of chemotherapy and nursing intervention, which can reduce the side effects of chemotherapy itself.


2020 ◽  
Vol 9 (2) ◽  
pp. 181
Author(s):  
Ni luh Putu Mahayani ◽  
Ni Komang Sukraandini ◽  
Ni Wayan Suniyadewi

AbstractBreast cancer sufferers have a tendency to experience a decrease of self esteem that make  patients shall showing symptoms such as blaming themself for what they experienced. One way to increase self esteem in cancer patients is by increasing family participation through family support. The aim of this study is to determine the relationship between family support and self esteem in breast cancer patients. This study was using cross sectional design. The study was taken place at the Surgical Oncology Polyclinic, found samples of 188 respondents which was selected with a purposive sampling technique.The results showed that the majority of respondents were in the category of moderate self-esteem were 98 respondents (52.1%) and the category of moderate family support were 96 respondents (51.1%). The Rank Spearmen test results shows p value 0,000 (p <ɑ), means there is a relationship between self-esteem and family support in breast cancer patients with r value of 0.566 (positive relationship). It is expected that the family will always support the patient in every process of treatment, whether in the form of physical, psychological or financial support that could increase the patient's self esteem


2021 ◽  
Vol 2 (2) ◽  
pp. 023-031
Author(s):  
Reynard Budy Setiawan ◽  
Desak Gede Agung Suprabawati ◽  
Jusak Nugraha

Background: Immunohistochemical testing is important in determining clinical diagnosis and therapy, and is useful as a prognostic and predictive factor, but it is not easy to do and is not always available. Breast cancer patient with higher low-density-lipoprotein cholesterol [LDL-c]. level tends to have larger tumor size, higher grade, higher proliferation rate, positive Human Epidermal growth factor Receptor-2 (HER2-neu) and occasionally come at late stage. High LDL-c receptors are found on the surface of breast cancer cells, where cancer cells will take up cholesterol in serum, and a metabolite of 27-hydroxycholesterol cholesterol will affect Estrogen Receptor-α. Methods: Analytical observational study by cross sectional method, during July 2020 – November 2020, at Oncology Clinic Dr. Soetomo Hospital Surabaya with a total sample size of 42. The data obtained were analyzed using the SPSS version 23.0 program, regression test and Chi-Square were performed for characteristic analysis and Chi-Square Fischer’s Exact Test were performed for correlation test between lipid profiles with hormonal status. Results: The mean value of LDL-c was 117.88 ± 33.89 mg/dL. In the analysis of the correlation between LDL-c and hormonal status, it was found that the majority of patients who had positive hormonal status had LDL-c levels of ≤160 mg/dL with p value = 0.049. ROC analysis shown LDL-c cut-off point of 132 mg/dL, p value = 0.034 (OR 5.031, 95% CI 1.159-21.848), sensitivity 46.7% and specificity 83.35%. Conclusion: There is a statistically significant relationship between LDL-c levels and hormonal status with the cut-off point of 132 mg/dL. The increase in LDL-c in serum increases the tendency of negative hormonal status, therefore LDL-c levels can be considerate in determining the therapy for breast cancer patients.


2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Eti Yerizel ◽  
Niki Astria ◽  
Daan Khambri

Background: Breast cancer is one of the most common cancers as well as one of the leading causes of cancer mortality in women worldwide. Cancer risk potentially continues to increase because of the many sources of exposure to carcinogenic chemical compounds. Carcinogenic compounds can contribute to free radical formation which might further interact and damage biomolecules such as lipids. Lipid peroxidation will increase malondialdehyde (MDA) levels, triggering gene mutations that leads to cancer.  Objective: The purpose of this research was to measure and compare MDA levels between breast cancer patients and control.Methods: This research was observational research using a cross-sectional comparative design of 30 breast cancer patients and 30 healthy controls. The place of this research is in Ropanasuri specialized surgery hospital and biochemical laboratory,  Faculty of Medicine, Andalas University, Padang. This research was conducted from August to September 2019. The MDA was measured using a spectrophotometer and an independent T-test was done.Results: The result of this research showed the mean MDA level of breast cancer patients was 3.98 ± 0.35 nmol/ml, higher than controls was 3.04 ± 0.36 nmol/ml with p-value = 0.001.Conclusion: There were significant differences in MDA levels among breast cancer patients and control in Ropanasuri specialized surgery hospital, Padang. 


2020 ◽  
Vol 15 (2) ◽  
pp. 110
Author(s):  
Alfat Hidayat ◽  
Luh Eka Purwani ◽  
Nunuk Nugrohowati

Breast cancer is the highest cause of death in women around the world. Common problems that arise in breast cancer patients is nutritional problems. The purpose of this study was to determine the relationship between chemotherapy, energy intake and nutritional status of stage II and III breast cancer patients at Fatmawati General Hospital in 2018-2019. The type of study was observational analytic with cross-sectional design on 34 breast cancer patients at Fatmawati General Hospital. The sample used purposive sampling technique by choosing patients who accomplish inclusion criterias including patients with compos mentis state, stage II and III, aged between 25–64 years old, have been taken chemotherapy without complication, outpatient, and agreed to be participant in this study. The exclusion criteria were patients with undernutrition before chemotherapy, received radiation and hormonal therapy, patients with severe infectious diseases (TBC and HIV/AIDS) and chronic diseases. The taken datas including nutritional status measured by Body Mass Index (BMI); chemotherapy status gained from medical record; and energy intake assessed by 3×24 hours food recall. The Chi-Square test showed there was no relationship between chemotherapy and nutritional status of breast cancer patients (p=1.000). However, there was a relationship between energy intake and nutritional status of breast cancer patients (p<0.05) with CI 95%, OR = 65.000 (4.905-861.448) which means that the patients with the intake of energy defi cit have 65 times bigger risk for malnutrition. The conclusion from this study is, there was a relationship between the energy intake with nutritional status of stage II and III breast cancer patients at Fatmawati General Hospital.


2020 ◽  
Vol 6 (1) ◽  
pp. 1-4
Author(s):  
Jumikha Tamara Sahmaulyana Sidauruk

Background: Breast cancer is a malignancy in breast tissue that can be originated from ductal epithelium and lobules. It is the main cause of death from cancer suffered by women in the world. Age and hormonal are important risk factors for breast cancer where the longer a person is exposed to estrogen, the higher is the risk for breast cancer. The estrogen receptor is one of the main prognostic and predictive factors examined in breast cancer and can be determinant for hormonal therapy. Objectives: This study aimed to discover the relation between age and estrogen receptor in breast cancer patients of RSUD Dr.Pirngadi Medan in 2018. Methods: This research was an analytical study with a cross-sectional design. The research sample was 96 breast cancer patients by medical records of RSUD Dr.Pirngadi Medan in 2018 collected by a consecutive sampling method. Analysis of the data in this study was done by univariate to describe the characteristics of research subjects, while bivariate analysis used the chi-square test method to analyze the relationship between age and estrogen receptor. Results: The patients with breast cancer in RSUD Dr.Pirngadi Medan 2018 was mostly >40 years old (79.2%), with negative estrogen receptor hormonal status (53%), status was married (99%), and the highest level of education was high school (54.2%). The results of the study showed that there was a relationship between age and estrogen receptor in breast cancer patients with p-value =0.007 (p value<0,05). Conclusion: There was a significant relationship between age and estrogen receptors and estrogen receptors in breast cancer patients in RSUD Dr.Pirngadi Medan 2018.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Lucilla Suparmi ◽  
Fransisca Anjar Rina Setyani

Objective: Chemotheraphy is one of theraphy managements for breast cancer patients. Chemotherapy has some side effects like nausea, gag, alpoesia, etc. Those can increase patients’ anxiety. Then, this anxiety will give impact on sleeping quality disoeder. This research aims to identify the anxiety level of breast cancer patients in chemotheraphy ODC room.Methods: This research used crossectional design. There are 32 respondents as research sample choosen by purposive sample technic.Results: The result shows that most repondents (68,75 %) didnot feel anxiety, 15,63% got mild anxiety, 9,38% got moderate and severe anxiety, and no one got panic anxiety. Most respondents (71,87) had good sleeping quality and 28,13% had poor sleeping quality. There is no relationship between level anxiety and sleeping quality of cancer patients with P value = 0,182.Conclusion: There is no relationship between level anxiety and sleeping quality of cancer patients. Nurse should do persoal approach to patients who are still having severe anxiety and poor sleeping qualitiy.


2020 ◽  
Vol 3 (3S) ◽  
pp. 136-140
Author(s):  
Yuliana Syam ◽  
Prihantono Prihantono ◽  
Elly Lilianty Sjattar ◽  
Arnis Puspitha

Chemotherapy is one of the modality therapies given to breast cancer patients to inhibit cancer cell metastases. The side effects of chemotherapy can suppress the hematopoietic system in the bone marrow and progressively affect the patient's prognosis. The aim of study was to analyze routine blood profiles as supporting data in developing nursing care for breast cancer patients undergoing chemotherapy at the RSU. Dr. Wahidin Sudirohusodo Makassar, Indonesia, from June to September 2018. This research was a descriptive research with descriptive survey method. This research was conducted at the RSU Surgical Polyclinic. Dr. Wahidin Sudirohusodo. The sampling technique used was Non-Probability Sampling a purposive sampling method. The participants of this study were patients with breast cancer who undergo chemotherapy treatment with a number of samples that meet the inclusion criteria as many as 32 people. of the 17 routine blood components which were assessed as one of the investigations in 32 patients were found to be 4 abnormal components, red blood cells mean ± SD (3.99 10^6/ uL ± 0.51), hemoglobin mean ± SD (11.18 gr/l ± 1.09), hematocrit mean ± SD (34.96% ± 3.96), and mean ± SD monocyte (15,043 10^3/uL ± 8.95). due to metastasis and side effects of chemotherapy treatment decrease red blood cells, hemoglobin, hematocrit, and increase in specific immune response through increase of monocytes indicator that performing phagocytosis.


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