scholarly journals Cocaine-Induced Pituitary and Subdural Brain Abscesses and the Treatment Challenges

Cureus ◽  
2021 ◽  
Author(s):  
Mansoor Zafar ◽  
Samuel Vaughan ◽  
Bao Khuu ◽  
Sophiya Shrestha ◽  
Elisabetta Porruvecchio ◽  
...  
Keyword(s):  
1999 ◽  
Vol 56 (11) ◽  
pp. 659-663 ◽  
Author(s):  
Nau ◽  
Behnke-Mursch

Die verursachenden Erreger von Hirnabszessen variieren in Abhängigkeit von der Grunderkrankung. Typisch sind Mischinfektionen aus Aerobiern und Anaerobiern. Hirnabszesse entwickeln sich meist subakut. Sensibelster Entzündungsparameter im Blut ist das C-reaktive Protein (bei 80–90% der Patien-ten erhöht). Die entscheidende diagnostische Maßnahme ist das kraniale CT ohne und mit Kontrastmittel (KM). Die rasche Kultur von Abszeßinhalt durch Punktion, Drainage oder Abszeßexzision ist entscheidend für die Erregeridentifikation. Eine alleinige Chemotherapie zur Abszeßbehandlung wird nur angewandt, wenn 1. multiple, tief gelegene und/oder sehr kleine Abszesse vorliegen oder 2. sich der Patient in einem so schlechten Allgemeinzustand befindet, daß ihm ein invasiver Eingriff nicht zugemutet werden kann oder 3. eine Hirnphlegmone und kein abgekapselter Abszeß vorliegt. Gebräuchliche operative Verfahren sind die Abszeßaspiration (meist nach stereotaktischer Abszeßpunktion), die offene Kraniotomie mit Abszeßexzision und die offene Abszeßevakuation ohne Kapselentfernung. Für die ungezielte Chemotherapie vor Erregernachweis bevorzugen wir die Kombination von Cefotaxim (3×2–4 g/d i.v.) mit Metronidazol (3–4×0,5 g/d i.v.). Kortikosteroide sind indiziert, wenn der Prozeß raumfordernd ist und eine Herniation droht oder multiple Abszesse vorliegen, die nur teilweise operativ angehbar sind, oder Hirnregionen mit besonderer Ödemneigung betroffen sind.


Author(s):  
Guilherme Finger ◽  
Maria Eduarda Conte Gripa ◽  
Tiago Paczko Bozko Cecchini ◽  
Tobias Ludwig do Nascimento

AbstractNocardia brain abscess is a rare clinical entity, accounting for 2% of all brain abscesses, associated with high morbidity and a mortality rate 3 times higher than brain abscesses caused by other bacteria. Proper investigation and treatment, characterized by a long-term antibiotic therapy, play an important role on the outcome of the patient. The authors describe a case of a patient without neurological comorbidities who developed clinical signs of right occipital lobe impairment and seizures, whose investigation demonstrated brain abscess caused by Nocardia spp. The patient was treated surgically followed by antibiotic therapy with a great outcome after 1 year of follow-up.


Author(s):  
Mohammad Jamali ◽  
Iman Ahrari ◽  
Keyvan Eghbal ◽  
Arash Saffarrian ◽  
Abbas Rakhsha ◽  
...  

Abstract Introduction Low-velocity penetrating brain injury is not prevalent. In some conditions such as childhood, and with the penetration of a pellet in weak spots of skull, low-velocity penetrating brain injury is expected; however, high-velocity projectiles have also been reported as the cause of severe brain injuries. One of the complications of penetrating brain injury is infection, in which different types of microorganisms play a role. The Streptococcus genus is the leading cause of abscess formation in non-traumatic patients. Multiple brain abscesses are not common. Case Presentation A 10-year-old boy with penetrating brain injury caused by an air gun pellet, who developed signs and symptoms of high intracranial pressure 18 days after the trauma. After the imaging scans and the detection of multiple brain abscesses and severe brain edema, prompt surgical intervention was performed for all three lesions in a single operation. The culture of a pus specimen was positive for Streptococcus species, and, with adequate antibiotic therapy, the patient was discharged from the hospital in good condition. Conclusion Brain injury with air gun shot is not prevalent. The penetration of a low-velocity air gun pellet in weak points of the skull (such as the orbit, the squamous portion of the temporal bone, and the cranial suture), specially in children, can cause significant brain injuries.


Neurosurgery ◽  
1977 ◽  
Vol 1 (3) ◽  
pp. 297-299 ◽  
Author(s):  
Kenneth J. Murray ◽  
Samuel K. Ackerman ◽  
Shelley N. Chou ◽  
Steven D. Douglas
Keyword(s):  

The Lancet ◽  
1988 ◽  
Vol 331 (8592) ◽  
pp. 994
Author(s):  
J. Richards ◽  
P.R. Sisson ◽  
H.R. Ingham
Keyword(s):  

2006 ◽  
Vol 27 (3) ◽  
pp. 213-222 ◽  
Author(s):  
Giuseppe Lucio Cascini ◽  
Diego De Palma ◽  
Federica Matteucci ◽  
Alberto Biggi ◽  
Pier Francesco Rambaldi ◽  
...  

1944 ◽  
Vol 88 (2) ◽  
pp. 155-160 ◽  
Author(s):  
Herbert M. Vann ◽  
Roland E. Miller
Keyword(s):  

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