scholarly journals The Relationship Between Hand Grip Strength and Cognitive Function in Older Adults: The Moderating Effect of Regular Exercise

2014 ◽  
Vol 25 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Sungeun Lee
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Grip Strength ◽  
Hand Grip Strength ◽  
Moderating Effect ◽  
Regular Exercise ◽  
Hand Grip ◽  
The Relationship

The Brain-Derived Neurotrophic Factor Functional Polymorphism and Hand Grip Strength Impact the Association between Brain-Derived Neurotrophic Factor Levels and Cognition in Older Adults in the United States

2022 ◽  
pp. 109980042110651
Author(s):  
Tingting Liu ◽  
Hongjin Li ◽  
Yvette P. Conley ◽  
Brian A. Primack ◽  
Jing Wang ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Grip Strength ◽  
Mental Status ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Hand Grip Strength ◽  
Hand Grip ◽  
Serum Bdnf

Introduction Aging is associated with subtle cognitive decline in attention, memory, executive function, processing speed, and reasoning. Although lower brain-derived neurotrophic factor (BDNF) has been linked to cognitive decline among older adults, it is not known if the association differs among individuals with various BDNF Val66Met (rs6265) genotypes. In addition, it is not clear whether these associations vary by hand grip strength or physical activity (PA). Methods A total of 2904 older adults were included in this study using data from the Health and Retirement Study. Associations between serum BDNF and measures of cognitive function were evaluated using multivariable linear regression models stratified by Met allele status. PA and hand grip strength were added to the model to evaluate whether including these variables altered associations between serum BDNF and cognition. Results Mean age was 71.4 years old, and mean body mass index was 28.3 kg/m2. Serum BDNF levels were positively associated with higher total cognitive score (beta = 0.34, p = .07), mental status (beta = 0.16, p = .07), and word recall (beta = 0.22, p =.04) among Met carriers, while serum BDNF levels were negatively associated with mental status (beta = −0.09, p = .07) among non-Met carriers. Furthermore, associations changed when hand grip strength was added to the model but not when PA was added to the model. Conclusions The BDNF Val66Met variant may moderate the association between serum BDNF levels and cognitive function in older adults. Furthermore, such associations differ according to hand grip strength but not PA.

scholarly journals Regular Exercise and Depressive Symptoms in Korean Older Adults

2021 ◽  
Vol 18 (1) ◽  
pp. 303
Author(s):  
Young-Mee Kim ◽  
Sung-il Cho
Keyword(s):  
Depressive Symptoms ◽  
Grip Strength ◽  
Multivariate Logistic Regression Analysis ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Hand Grip Strength ◽  
Regular Exercise ◽  
Older Individuals ◽  
Related Factors ◽  
Hand Grip

Prior studies have found that exercise has a positive effect on depressive symptoms in the general population. For older individuals, however, the association between exercise and depressive symptoms is conclusive. We examined whether regular exercise is related to depressive symptoms in 5379 Korean adults aged ≥55 years using data from a 2016 survey administered in the Korean Longitudinal Study of Aging. We used the 10-item Center for Epidemiological Studies–Depression scale to assess depressive symptoms. We performed a multivariate logistic regression analysis to investigate the relationship between regular exercise and depressive symptoms, adjusting for sociodemographic characteristics, self-rated health, number of chronic diseases, body mass index, hand-grip strength, physical disability, cognitive impairment, and health behavior. Interaction terms, including regular exercise and health-related factors, were also added. We found that a lack of regular exercise was significantly related to an increased frequency of depressive symptoms (OR = 1.18, 95% CI = 1.03–1.35). Moreover, hand-grip strength may increase the effect of regular exercise on depressive symptoms in individuals 65 years and older (OR = 1.01 vs. 1.70, 95% CI = 1.05–1.96). Our results suggest that it is important to encourage older individuals to exercise regularly as a means of relieving depressive symptoms.

scholarly journals Hand Grip Strength and Gender: Allometric Normalization in Older Adults and Implications for the NIOSH Lifting Equation

2017 ◽  
Vol 7 (2) ◽  
pp. 63-68 ◽  
Author(s):  
Trish Gail Sevene ◽  
Joseph Berning ◽  
Chad Harris ◽  
Mike Climstein ◽  
Kent Jason Adams ◽  
...  
Keyword(s):  
Older Adults ◽  
Grip Strength ◽  
Hand Grip Strength ◽  
Hand Grip ◽  
And Gender ◽  
Niosh Lifting Equation

scholarly journals The Relationship between Muscular Strength and Depression in Older Adults with Chronic Disease Comorbidity

2020 ◽  
Vol 17 (18) ◽  
pp. 6830
Author(s):  
Jae-Moo Lee ◽  
Edward J. Ryan
Keyword(s):  
Older Adults ◽  
Chronic Disease ◽  
Older People ◽  
Grip Strength ◽  
Muscular Strength ◽  
Statistical Tests ◽  
Ministry Of Health ◽  
Hand Grip ◽  
Prevalence Of Depression ◽  
The Relationship

Older adults with disease and disability are particularly vulnerable to experiencing more severe consequences of depression. The purpose of the present study is to investigate the relationship between disease comorbidities (number of disease: ND0, 1 disease: ND1 and 2 or more diseases: ND ≥ 2), hand grip strength (low HGS and high HGS), and the prevalence of depression in Korean older adults. Data from the living profiles of older people survey that was conducted by the ministry of health and welfare in Korea were utilized. Data for 6107 females and 4347 males were appropriate for statistical tests. The results demonstrated that depression was more prevalent as ND increased (p < 0.01). In addition, HGS appeared lower as ND increased in both male (p < 0.01) and female subjects (p < 0.01). Furthermore, relative to ND0 and low HGS, ND0 and high HGS showed a ~65% reduction in the prevalence of depression (p < 0.01). After adjusting for age, the prevalence of depression was reduced by ~60% in the subgroup with ND0 and high HGS relative to ND0 and low HGS (p < 0.01). These data demonstrate that muscular strength indices such as HGS may be useful when assessing depression in older adults. Further research in this area is warranted.

scholarly journals Hand-grip strength among older adults in Singapore: a comparison with international norms and associative factors

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Hui Lin Ong ◽  
Edimansyah Abdin ◽  
Boon Yiang Chua ◽  
Yunjue Zhang ◽  
Esmond Seow ◽  
...  
Keyword(s):  
Older Adults ◽  
Grip Strength ◽  
Hand Grip Strength ◽  
International Norms ◽  
Hand Grip

scholarly journals Hand grip strength and cognitive function among elderly cancer survivors

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0197909 ◽  
Author(s):  
Lin Yang ◽  
Ai Koyanagi ◽  
Lee Smith ◽  
Liang Hu ◽  
Graham A. Colditz ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Cancer Survivors ◽  
Grip Strength ◽  
Hand Grip Strength ◽  
Hand Grip

scholarly journals The Relationship of Digit Ratio (2D:4D) With Cerebral Lateralization and Grip Strength in Elite Swimmers

2018 ◽  
Vol 6 (4) ◽  
pp. 84
Author(s):  
Hakan Acar ◽  
Nebahat Eler
Keyword(s):  
Grip Strength ◽  
Hand Preference ◽  
Hand Grip Strength ◽  
Dominant Hand ◽  
Men And Women ◽  
Left Hand ◽  
Hand Grip ◽  
Elite Swimmers ◽  
The Relationship ◽  
Right And Left Hand

The index finger and the 4th finger ratio (2D:4D) is the indicator of the prenatal testosterone. The aim of this study is to investigate the relationship between 2D:4D, hand preference and hand grip strength in swimmers. A total of 80 elite swimmers, participated in the study. Height, body weight, body mass index (BMI), hand 2D:4D finger measurements and hand grip strength tests were performed for athletes. The hand preference was determined by the Oldfield questionnaire and it was evaluated according to the Geschwind score. The data were recorded in the SPSS 20 program and p<0.05 was considered as statistically significant. It was found that in both men and women, a negative correlation was found between right and left hand 2D:4D and both dominant (DHGS) and non-dominant hand grip strength (NDHGS) values. It was found that men had lower 2D:4D ratio than women. For both right and left handed, there was a statistically significant difference between the right and left hand 2D:4D ratios in both men and women (p<0.05) and the dominant hand (DH) 2D:4D ratios were found to be lower than non-dominant hand (NDH) 2D:4D ratios in both men and women (p<0.05)  It can be said that the 2D:4D ratios may be the effect of determining the hand preference, the grip strength and therefore the strength.

scholarly journals A single-arm feasibility study of community-delivered Baduanjin (Qigong practice of the eight Brocades) training for frail older adults

2020 ◽  
Author(s):  
Xiao Liu ◽  
Jean Wei Ting Seah ◽  
Benedict Wei Jun Pang ◽  
Mary Ann Tsao ◽  
Falong Gu ◽  
...  
Keyword(s):  
Older Adults ◽  
Adverse Events ◽  
Training Program ◽  
Grip Strength ◽  
Fall Risk ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Frail Older Adults ◽  
Knee Extension Strength ◽  
Hand Grip

Abstract Background: Frailty is a common geriatric syndrome, characterized by reduced physiologic reserve and increased vulnerability to stressors, due to cumulative decline in multiple physiological systems. We studied the feasibility of a community-delivered Baduanjin (BDJ) training program among pre-frail/frail community-dwelling older people. We examined 1) safety (adverse events), physical and psychological effects; and 2) feasibility of recruitment, retention, adherence; recruitment efforts and any program challenges, so as to inform future studies.Methods: Our study was a single arm pre-post study in a community setting. Sixteen week group BDJ training (2x/week in the first 4 weeks, and 3x/week thereafter) co-designed and implemented by community-based providers in Singapore. Recruitment, attendance and adverse events were recorded throughout the training. A participants’ survey was also administered after the training program. Effects of the intervention on physical and functional outcomes (hand grip strength, knee extension strength, Time Up and Go (TUG), Physiological Profile Assessment (PPA), 30-second Sit-to-Stand test, 6-meter fast gait speed test), frailty outcomes (frailty score and status), and other outcomes (Maastricht Questionnaire (MQ), Fall Efficacy Scale (FES), Montreal Cognitive Assessment (MoCA), Geriatric Depression Scale (GDS), and EQ-5D-5L) were examined before and after the program.Results: Of 31 older adults screened to be frail, 15 met inclusion criteria and 3 refused participation, resulting in 12 older adults (9 women) enrolled into the program. During the program, one participant was hospitalized (unrelated to BDJ training) and the other 11 (aged 77±6 years; 2 frail, 9 prefrail at baseline) completed the program with average overall attendance of 89%. Most (89%) of the 44 training sessions had attendance >80%. The program received positive feedback with no training-related adverse events. Participants either reversed (n=2) or maintained (n=9) their frailty statuses. There post-training outcomes in hand grip strength, knee extension strength, TUG , MQ , FES , MoCA , GDS and EQ-5D-5L index score appeared to be better. The reduction of frailty and PPA fall risk scores were of moderate-to-large effect size. Conclusions: Community-delivered BDJ training program was safe and feasible for prefrail/frail older adults with the potential to improve physical and cognitive function, reduce fall risk, improve psychological well-being, and reverse frailty status.

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