scholarly journals Pulmonary Adenofibroma in an Elderly Male with Recurrent Soft Tissue Sarcoma

2021 ◽  
Author(s):  
Sandhya Devi Pasupathy ◽  
Archana Lakshmanan ◽  
S Annapurneswari
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Benign Lesion ◽  
Female Genital Tract ◽  
Anterior Segment ◽  
Pulmonary Blastoma ◽  
Soft Tissue Tumour ◽  
Biphasic Pattern ◽  
Tissue Tumour ◽  
Stromal Component

Pulmonary Adenofibroma (PAF) is a rare soft tissue tumour of the lung. It is a benign lesion, having a biphasic pattern with an admixture of epithelial and stromal components and has resemblance to fibroadenoma of the breast and adenofibroma of the female genital tract. The diagnosis can be challenging and it has to be delineated from other entities with biphasic pattern, like pulmonary hamartoma, pulmonary blastoma, intrapulmonary solitary fibrous tumour and metastases from soft tissue and visceral sarcomas, as each tumour has its own therapeutic and prognostic implications. Here, we report a case of a 73-year-old male, a known case of recurrent soft tissue sarcoma of the thigh, who presented with solitary pulmonary lesion. The patient was a non-smoker and did not have any specific respiratory complaints. On staging work-up with a Positron Emission Tomography and Computed Tomography (PET-CT), a hypermetabolic lesion was identified in the anterior segment of right upper lobe of the lung, following which he underwent right lobectomy. The tumour was a solitary lesion located near the hilum and on histology showed a biphasic pattern with scattered glandular spaces lined by columnar epithelium set in a hyalinised spindle cell stroma. The cells showed mild pleomorphism with oval to elongated nuclei and indistinct cytoplasm. On immunohistochemistry, the epithelial component showed positivity for Cytokeratin (CK), Epithelial Membrane Antigen (EMA), Thyroid Transcription Factor-1 (TTF-1) and Napsin-A and the stromal component showed positivity for Vimentin, Desmin, Smooth Muscle Actin (SMA) and H-Caldesmon (High molecular weight isoform-Caldesmon). With the given histological and immunohistochemistry findings, a diagnosis of PAF was rendered.

scholarly journals The Effectiveness of “Two-Week” Referrals for Suspected Bone and Soft Tissue Sarcoma

Sarcoma ◽  
2007 ◽  
Vol 2007 ◽  
pp. 1-3 ◽  
Author(s):  
A. Malik ◽  
L. Wigney ◽  
S. Murray ◽  
C. H. Gerrand
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
General Practitioners ◽  
Diagnosis And Treatment ◽  
Soft Tissue Tumour ◽  
Malignant Tumours ◽  
Urgent Referral ◽  
The North ◽  
Tissue Tumour ◽  
Time To Diagnosis

The two-week “wait” target introduced in 2000 requires that patients with suspected cancer referred by general practitioners should be seen within two weeks. We reviewed patients who had been referred under this standard to the North of England Bone and Soft Tissue Tumour Service, to determine if the referral guidelines had been followed, and what proportion of patients referred under the guideline had malignant tumours. 40 patients were referred under the guideline between January 2004 and December 2005. Ten of these patients (2548%) had malignant tumours, compared with 243 of 507 (48%) of those referred from other sources. In 9 of the 40 cases, the patient did not meet the criteria for urgent referral. Although this target has focussed attention on shortening the time to diagnosis and treatment, prioritising patients referred from general practitioners has the potential to disadvantage those with malignant tumours referred from other sources.

scholarly journals Synovial sarcoma

2014 ◽  
Vol 18 (2) ◽  
Author(s):  
Sucari S.C. Vlok ◽  
Georg W.W. Wagener ◽  
Dan Zaharie
Keyword(s):  
Soft Tissue ◽  
Synovial Sarcoma ◽  
Soft Tissue Mass ◽  
Benign Lesion ◽  
Soft Tissue Sarcomas ◽  
Soft Tissue Tumour ◽  
Tissue Mass ◽  
Young Adult Patient ◽  
Tissue Tumour ◽  
Insidious Onset

Synovial sarcoma is a malignant, predominantly juxta-articular, soft-tissue tumour representing approximately 10% of all soft-tissue sarcomas. Frequently initially incorrectly diagnosed as a benign lesion, it should be considered as a diagnosis when a young adult patient presents with a calcified juxta-articular soft-tissue mass of insidious onset.

scholarly journals Angiomyofibroblastoma of scalp: a rare soft tissue tumour at an unusual site

2020 ◽  
Vol 7 (4) ◽  
pp. 1301
Author(s):  
Sajid Hussain
Keyword(s):  
Soft Tissue ◽  
Female Genital Tract ◽  
Reproductive Age ◽  
Soft Tissue Tumour ◽  
Unusual Site ◽  
Posterior Aspect ◽  
Medical College ◽  
Tissue Tumour ◽  
Slow Growing ◽  
Reproductive Age Group

Angimyofibroblastoma is a very rare, benign mesenchymal soft tissue tumour which involves the vulvovaginal area of females of reproductive age group. These tumours are usually slow growing and painless which has a very low tendency for local recurrence. In women it is common in female genital tract, vulva, and posterior perivesical space. In men it occurs in spermatic cord. Here a report of 47 year old male patient from VMKV Medical College and Hospital, Salem was presented with a swelling in the posterior aspect of scalp from 6 months with no any associated symptoms. A preoperative diagnosis of dermoid scalp was made and patient was subjected for excision.

Guide to pseudotumours and soft tissue tumour mimics

2017 ◽  
Vol 31 (3) ◽  
pp. 204-215 ◽  
Author(s):  
Kethesparan Paramesparan ◽  
Amit Shah ◽  
Winston J. Rennie
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumour ◽  
Tissue Tumour

Musculoskeletal CPD revision: Cases from the New Zealand bone and soft tissue tumour registry

2012 ◽  
Vol 56 (1) ◽  
pp. 96-99
Author(s):  
Yuranga Dilan Weerakkody ◽  
Michael Dray ◽  
Clinton Pinto ◽  
Michael Rosenfeldt ◽  
Michael Flint
Keyword(s):  
New Zealand ◽  
Soft Tissue ◽  
Soft Tissue Tumour ◽  
Tissue Tumour

Mesenteric leiomyosarcoma : A rare mesenchymal soft tissue tumour in a dog

2020 ◽  
Vol 44 (3) ◽  
pp. 189-191
Author(s):  
N. Babu Prasath ◽  
J Selvaraj ◽  
M Sasikala ◽  
S. Senthilkumar
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumour ◽  
Tissue Tumour

Rare case of angiofibroma presenting as perineal hernia

2021 ◽  
Vol 14 (1) ◽  
pp. e236661
Author(s):  
Ruchika Kumari ◽  
Cherring Tandup ◽  
Ambuj Agarwal ◽  
Anish Chowdhury
Keyword(s):  
Soft Tissue ◽  
Case Reports ◽  
En Bloc Resection ◽  
Perineal Hernia ◽  
Pathological Examination ◽  
Soft Tissue Tumour ◽  
Open Approach ◽  
En Bloc ◽  
Rare Tumour ◽  
Tissue Tumour

Angiofibroma is a benign soft tissue tumour presenting as a gradually progressive swelling in the vulvovaginal area in women and in the inguinoscrotal region in men. Being a rare tumour, there are only a few case reports in the literature, and among them, presentation as perineal herniation is very rare. En bloc resection of angiofibroma either via laparoscopic or open approach is the choice of treatment to avoid recurrence. Detailed pathological examination and immunohistochemistry workup are imperative to distinguish it from various mesenchymal tumours. Perineal hernia is itself rare and may occur spontaneously or following abdominoperineal resection, sacrectomy or pelvic exenteration. Surgical repair via open transabdominal and transperineal approaches has been described. Here, we report a case of a young woman who presented with spontaneous reducible perineal hernia with a soft tissue tumour as its content, which on histopathological investigation was found to be an angiofibroma.

scholarly journals Extraskeletal Mesenchymal Chondrosarcoma

2018 ◽  
Vol 142 (11) ◽  
pp. 1421-1424 ◽  
Author(s):  
Komal Arora ◽  
Nicole D. Riddle
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Soft Tissues ◽  
Hyaline Cartilage ◽  
Mesenchymal Chondrosarcoma ◽  
Small Cells ◽  
Diagnostic Challenge ◽  
Biphasic Pattern ◽  
Biopsy Specimens ◽  
Extraskeletal Mesenchymal Chondrosarcoma

Extraskeletal mesenchymal chondrosarcoma is a rare soft tissue sarcoma arising from soft tissues, mainly of the lower extremities, meninges, and orbits. It usually presents during the second to third decades of life, and has a slight predominance in females. Histologically, it has a typical biphasic pattern comprising small cells and islands of hyaline cartilage. It can pose a diagnostic challenge in small biopsy specimens where 1 of the 2 components can be absent. The prognosis is extremely variable; survival varies depending on the location of the tumor.

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