EVALUATION OF ANALGESIC EFFECT OF TAB TRAILOKYA VIJAYA VATI IN POST-OPERATIVE PAIN IN KSHARKARMA PATIENTS: AN OBSERVATIONAL STUDY

Despite the advances in technology and robotics, the basics of surgical management are not changed drastically. The science of life, Ayurveda has extensive knowledge of surgeries, including complicated procedures mentioned in the classical texts. However, with time, the ability of anaesthetics and analgesic agents has been lost. This resulted in the lagging of Ayurvedic Surgical wisdom and the rise of modern analgesics and anaesthetics in the market. These current products have potential side effects, and hence a safer and better alternative to these products can boost Ayurveda Surgery worldwide. Trailokya Vijaya Vati (TVV) is one such Ayurvedic formulation that is explained for its potent analgesic activity. The present study was conducted to evaluate the safety and efficacy of TVV in post-operative pain management in patients undergoing anorectal procedures. The observational trial suggested a reduction in time to sleep (p < 0.05), less incidence of insomnia and undisturbed sleep in the treatment group than the control. The formulation was also well tolerated with no or minimal requirement of rescue analgesics. The efficacy observed in the study suggests the formulation can be explored further on a larger population with a diverse activity profile.

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POST-OPERATIVE PAIN RELIEF FOR LOWER ABDOMINAL SURGERY

The Professional Medical Journal ◽

10.29309/tpmj/2005.12.03.5134 ◽

2005 ◽

Vol 12 (03) ◽

pp. 340-345

Author(s):

ROBINA FIRDOUS

Keyword(s):

Pain Management ◽

Side Effects ◽

Pain Relief ◽

Abdominal Surgery ◽

Opioid Receptors ◽

Acute Pain ◽

Alternate Route ◽

Parenteral Route ◽

Group I ◽

Post Operative Pain

The severity of post-operative pain and the lack of efforts in relievingit have led to the involvement of Anaesthesiologists in the management of post-operative and acute pain. Parenteralopiates have been utilized for post-operative pain management. The identification of the opioid receptors on substantiagelatinosa has provided an alternate route i.e 1 the epidural route - for administering opiates. Objectives: To evaluateand compare the efficacy and side effects of parenteral Buprenorphine with those of Extradural Buprenorphine.Setting: Department of Anaesthesia, District Headquarter Hospital, Faisalabad. Period: The data was collected duringthe last three and a half years. Materials and Methods: Sixty adult patients of either sex and ages ranging from 35-45years, who underwent lower abdominal surgery, were randomly selected for the study. They were equally divided intotwo groups. Group I patients were administered Buprenorphine 0.3 mg through the epidural catheter in extraduralspace. Group II patients were given Buprenorphine 0.3 mg intramuscularly. Results: Buprenorphine through theepidural route gives better analgesia with fewer side effects as compared with the parenteral route.

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Children's nurses’ post-operative pain management practices: An observational study

International Journal of Nursing Studies ◽

10.1016/j.ijnurstu.2006.03.010 ◽

2007 ◽

Vol 44 (6) ◽

pp. 869-881 ◽

Cited By ~ 51

Author(s):

Alison Twycross

Keyword(s):

Pain Management ◽

Observational Study ◽

Management Practices ◽

Post Operative Pain

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Pharmacology of pain management in general practice

InnovAiT Education and inspiration for general practice ◽

10.1177/1755738016665132 ◽

2016 ◽

Vol 9 (12) ◽

pp. 742-752

Author(s):

Christopher Evans ◽

Alison Hoggarth ◽

Colm Lanigan

Keyword(s):

Chronic Pain ◽

Pain Management ◽

Side Effects ◽

Wide Spectrum ◽

Pharmacological Action ◽

The Novel ◽

Drug Dosing ◽

Pain Pathways ◽

Analgesic Agents ◽

First Time

Pain is described as the fifth vital sign, yet its importance is frequently not fully recognised, despite 68 000 000 analgesic prescriptions being dispensed annually. GPs treat pain in the context of a wide spectrum of patient conditions and co-morbidities, recognising potential drug interactions and side-effects. They also factor in the patient’s anxieties, coping strategies, cultural background and previous experiences of pain. It is no wonder that we frequently do not get it right first time. This article discusses the pharmacological action of the major groups of analgesic drugs, considers common pitfalls, and suggests appropriate drug dosing. A titrated multi-modal approach is recommended to target nociceptor pain pathways, and to reduce the side-effects caused by large doses of monotherapy. It discusses the novel use of analgesic agents previously only used for chronic pain. It does not, however, discuss acute-on-chronic pain, drug tolerance, drug addiction or complex pain management.

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Perioperative Surgical Pain Management

Primary Dental Journal ◽

10.1177/205016841800700411 ◽

2018 ◽

Vol 7 (4) ◽

pp. 45-50

Author(s):

Nadine Khawaja

Keyword(s):

Pain Management ◽

Side Effects ◽

Dental Pain ◽

Over The Counter ◽

Pain Experience ◽

Surgical Pain ◽

Post Operative Pain ◽

The Impact ◽

Acute Dental Pain

Acute dental pain continues to be under-managed, despite availability of several effective over-the-counter analgesics. This article discusses the mechanisms underlying the pain experience, the impact of post-operative pain and how to overcome barriers to optimal pain management. Prescribing using principles of multi-modal analgesia will be covered as well as discussion of associated side effects.

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Observational study of post-operative pain control before and after the implementation of a clinical practice guideline for postoperative pain management

Medicina Clínica (English Edition) ◽

10.1016/j.medcle.2019.01.033 ◽

2019 ◽

Vol 153 (8) ◽

pp. 312-318

Author(s):

Ángeles Mesas Idáñez ◽

Cristina Aguilera Martin ◽

Concepción Muñoz Alcaide ◽

Antonio Vallano Ferraz ◽

M. Victoria Ribera Canudas ◽

...

Keyword(s):

Clinical Practice ◽

Pain Management ◽

Postoperative Pain ◽

Observational Study ◽

Clinical Practice Guideline ◽

Practice Guideline ◽

Pain Control ◽

Postoperative Pain Management ◽

Post Operative Pain ◽

Before And After

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Principles of pain management

Current Surgical Guidelines ◽

10.1093/med/9780198794769.003.0021 ◽

2018 ◽

pp. 191-198

Author(s):

Abdullah Jibawi ◽

Mohamed Baguneid ◽

Arnab Bhowmick

Keyword(s):

Neuropathic Pain ◽

Pain Management ◽

Side Effects ◽

Cancer Pain ◽

Surgical Trauma ◽

Who Analgesic Ladder ◽

Vital Part ◽

Quick Recovery ◽

Post Operative Pain ◽

Operative Assessment

Post-operative pain is related to surgical trauma and pre-operative assessment plays a vital part in post-operative pain management. Both pharmacological and non-pharmacological options should be discussed with the patient and do help in quick recovery. The ABCDE approach should be followed whilst assessing the pain postoperatively. WHO analgesic ladder is recommended for pain management. Effective management of side-effects of analgesia and re-evaluation of pain management are also important. The same principle is applied for cancer pain and neuropathic pain.

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Comparison of Efficacy and Safety of Patient Taking Pregabalin and Desvenlafaxine in Neuropathic Pain

Volume 5 - 2020, Issue 9 - September - International Journal of Innovative Science and Research Technology ◽

10.38124/ijisrt20aug221 ◽

2020 ◽

Vol 5 (8) ◽

pp. 231-235

Author(s):

Neenu Rachel Santhosh ◽

Ajay K Raj ◽

Rahmathullah SN ◽

Dr.Abdu Rahman ◽

Sereena A

Keyword(s):

Neuropathic Pain ◽

Side Effects ◽

Pain Relief ◽

Observational Study ◽

Prospective Observational Study ◽

Efficacy And Safety ◽

Safety And Efficacy ◽

Visual Analogue Pain ◽

Pain Scores ◽

Prolonged Pain

To compare safety and efficacy of pregabalin and desvenlafaxine respectively for treating Neuropathic Pain. 04 patients were entered into a prospective observational study of pregabalin and desvenlafaxine in neuropathic pain for 6 months. Patients were randomly arranged into 2 groups, 52 patients received pregabalin and other group of 52 patients received desvenlafaxine. The initialassessement were made during the first visit and two subsequent reviews were done in 2 months interval, up to 6 months. Visual analogue pain scores, incidence of side effects were measured. The pain scores(mean±S.D.) were 5.37±1.14 and 6.7±1.39 respectively for desvenlafaxine and pregabalin.The low pain score of desvenlafaxine was associated with prolonged pain relief. There were pronounced differences in incidence of side effect between the two drugs: pregabalin, 36.5% compared to desvenlafaxine, 7%. The study findings revealed that desvenlafaxine is more safe and efficacious than pregabalin. Thus this study recommends the use of desvenlafaxine for neuropathic pain over pregabalin

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A Clinical Trial of Hydroxyethylrutosides in the Treatment of Haemorrhoids of Pregnancy

Journal of International Medical Research ◽

10.1177/030006059202000107 ◽

1992 ◽

Vol 20 (1) ◽

pp. 54-60 ◽

Cited By ~ 32

Author(s):

H Wijayanegara ◽

JC Mose ◽

L Achmad ◽

R Sobarna ◽

W Permadi

Keyword(s):

Clinical Trial ◽

Treatment Group ◽

Side Effects ◽

Active Treatment ◽

Controlled Trial ◽

Active Treatment Group ◽

Subjective Symptoms ◽

Drug Related Problems ◽

Double Blind ◽

Safety And Efficacy

The safety and efficacy of 500 mg O-( β-hydroxyethyl)rutosides given orally twice daily in the treatment of 97 patients with first-, second-, or third-degree haemorrhoids were investigated in a double-blind, randomized placebo-controlled trial. The rutosides produced a significant ( P < 0.001) improvement in patient-assessed subjective symptoms (pain, bleeding, exudation and pruritus) compared with placebo. There was also a significant ( P < 0.0001) improvement in clinician-assessed subjective and objective signs (bleeding, inflammation and dilatation of the haemorrhoidal plexus) after 2 and 4 weeks' treatment compared with placebo. There were three mild, transient side-effects reported in the active treatment group and no drug-related problems in the pregnancy or delivery were observed. The results suggest that O-( β-hydroxyethyl)rutosides provide a safe and effective treatment for women with haemorrhoids of pregnancy.

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