scholarly journals Synthesis, Characterization and Investigation of Antimicrobial Activity of a New Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) Phenol and Its Cu(II) and Ni(II) Complexes

2020 ◽  
pp. 30-38
Author(s):  
Musarat Farjana Yesmin ◽  
Farzana Khanm Camellia ◽  
Modina Bashar ◽  
Md. Sajjad Hossain ◽  
Saiyad Nasira ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Conductivity Measurements ◽  
Physico Chemical ◽  
Square Planar ◽  
Infrared Spectral ◽  
Chemical Techniques ◽  
And Staphylococcus Aureus

New complexes of Cu (II) and Ni (II) of the Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) phenol were synthesized and characterized by analytical and  physico-chemical techniques including magnetic susceptibility, conductivity measurements, electronic and IR spectral studies. The infrared spectral studies revealed the tetra-dentate nature of the Schiff base in the complexes. On the basis of all characterizations, square- planar geometry has proposed for all the obtained complexes. The complexes showed moderate antimicrobial activity against Escherichia coli and Staphylococcus aureus.

scholarly journals Unsymmetrical Schiff Base Functionalized as Monobasic Tridentate Ligand on Complexation with Some Transition Metal Ions

2012 ◽  
Vol 9 (2) ◽  
pp. 532-544
Author(s):  
Bibhesh K. Singh ◽  
Narendar Bhojak ◽  
Anant Prakash
Keyword(s):  
Schiff Base ◽  
Transition Metal Ions ◽  
Tridentate Ligand ◽  
Planar Geometry ◽  
Physico Chemical ◽  
Square Planar ◽  
Unsymmetrical Schiff Base ◽  
Mm2 Calculations ◽  
Microbial Potential

Cu(II), Co(II), Ni(II) and Mn(II) complexes of Schiff base derived from 2-aminophenol and pyrrole-2- carbaldehyde have been prepared. The complexes are formed by coordination of N and O atoms of the ligand. Their structures were characterized by physico-chemical and spectroscopic methods. Molecular structure of the complexes has been optimized by MM2 calculations and suggests a tetrahedral/ square planar geometry. The bio-efficacy of the ligand and their complexes has been examined against the growth of bacteriain vitroto evaluate their anti-microbial potential.

scholarly journals Synthesis, spectral studies and antibacterial activity of Cu(II), Co(II) and Ni(II) complexes of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol- -1-yl)methyl]hydrazone

2009 ◽  
Vol 74 (8-9) ◽  
pp. 927-938 ◽  
Author(s):  
Paulmony Tharmaraj ◽  
Deivasigamani Kodimunthiri ◽  
Clarence Sheela ◽  
Shanmuga Priya
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Free Ligand ◽  
Esr Spectra ◽  
Octahedral Geometry ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Hydrazone Ligand ◽  
Square Planar

A new series of Cu(II), Co(II) and Ni(II) complexes with the 1-(2- -hydroxyphenyl)-3-phenyl-2-propen-1-one, N2-[(3,5-dimethyl-1H-pyrazol-1- -yl)methyl]hydrazone ligand, C21H22N4O (LH), were synthesized by the reaction of 1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one, hydrazone with (3,5-dimethyl- 1H-pyrazol-1-yl)methanol and characterized. The nature of the bonding and geometry of the complexes were deduced from elemental analysis, IR, electronic and 1H-NMR spectroscopy, and magnetic susceptibility and conductivity measurements. The studies indicated square-planar, tetrahedral and octahedral geometry for the copper(II), cobalt(II) and nickel(II) complexes, respectively. The ESR spectra of the copper(II) complex in acetonitrile at 300 and 77 K were recorded and their salient features are reported. The electrochemical behavior of the copper (II) complex was studied by cyclic voltammetry. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus, Salmonella enterica typhi, Escherichia coli and Bacillus subtilis by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.

scholarly journals Transition metal M(II) complexes with isonicotinoylhydrazone-9-anthraldehyde

2010 ◽  
Vol 75 (11) ◽  
pp. 1515-1531 ◽  
Author(s):  
M.L. Dianu ◽  
A. Kriza ◽  
N. Stanica ◽  
A.M. Musuc
Keyword(s):  
Thermal Analyses ◽  
Thermal Studies ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Tetrahedral Geometry ◽  
Physico Chemical ◽  
Pyridine Nitrogen ◽  
Infrared Spectral ◽  
Nitrate Complexes

New complexes of isonicotinoylhydrazone-9-anthraldehyde with Cu(II), Co(II) and Ni(II) have been prepared and characterized by analytical and physico-chemical techniques, such as elemental and thermal analyses, magnetic susceptibility and conductivity measurements, and electronic, EPR and IR spectral studies. The infrared spectral studies revealed the bidentate or monodentate nature of the Schiff base in the complexes; the pyridine nitrogen does not participate in the coordination. A tetrahedral geometry is suggested for the nitrate-complexes and an octahedral geometry for the others. Thermal studies support the chemical formulation of these complexes.

scholarly journals Synthesis, Characterization, and Biological Activity of Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) Complexes of N-Thiophenoyl-N′-Phenylthiocarbohydrazide

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
M. Yadav ◽  
Debasis Behera
Keyword(s):  
Magnetic Susceptibility ◽  
Biological Activity ◽  
Octahedral Geometry ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Tetradentate Ligand ◽  
Tetrahedral Geometry ◽  
Square Planar ◽  
Infrared Spectral ◽  
Bacteria And Fungi

Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) complex of N-thiophenoyl -N′-phenylthiocarbohydrazide (H2TPTH) have been synthesized and characterized by elemental analysis, magnetic susceptibility measurements, infrared, NMR, electronic, and ESR spectral studies. The complexes were found to have compositions [Mn(H TPTH)2], [Co(TPTH) (H2O)2], [Ni(TPTH) (H2O)2], [Cu(TPTH)], [Zn(H TPTH)], [Cd(H TPTH)2], and [Fe(H TPTH)2(EtOH)]. The magnetic and electronic spectral studies suggest square planar geometry for [Cu(TPTH)], tetrahedral geometry for [Zn(TPTH)] and [Cd(H TPTH)2], and octahedral geometry for rest of the complexes. The infrared spectral studies of the 1 : 1 deprotonated complexes suggest bonding through enolic oxygen, thiolato sulfur, and both the hydrazinic nitrogens. Thus, H2TPTH acts as a binegative tetradentate ligand. H2TPTH and its metal complexes have been screened against several bacteria and fungi.

scholarly journals Spectroscopic and Biological Studies on Newly Synthesized Cobalt (II) and Nickel (II) Complexes with 2-Acetyl Coumarone Semicarbazone and 2-Acetyl Coumarone Thiosemicarbazone

2013 ◽  
Vol 2013 ◽  
pp. 1-7
Author(s):  
Sanjay Goel ◽  
Sulekh Chandra ◽  
Sudhanshu Dhar Dwivedi
Keyword(s):  
Magnetic Susceptibility ◽  
Metal Complexes ◽  
Antioxidant Activities ◽  
Molar Conductance ◽  
Metal Salts ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Square Planar ◽  
Biological Studies ◽  
Infrared Spectral

Co(II) and Ni(II) complexes of general composition ML2X2(M = Co(II), Ni(II); X = Cl−,NO3 −) were synthesized by the condensation of metal salts with semicarbazone/thiosemicarbazone derived from 2-acetyl coumarone. The ligands and metal complexes were characterized by NMR, elemental analysis, molar conductance, magnetic susceptibility measurements, IR, and atomic absorption spectral studies. On the basis of electronic, molar conductance and infrared spectral studies, the complexes were found to have square planar geometry. The Schiff bases and their metal complexes were tested for their antibacterial and antioxidant activities.

scholarly journals Synthesis, Characterization and Toxicity Evaluation of Cu(II), Mn(II), Co(II), Ni(II), Pd(II) Complexes with Ligand Derived from Hydrazinecarbothioamide

2018 ◽  
Vol 69 (11) ◽  
pp. 2959-2963 ◽  
Author(s):  
Elena Pahontu ◽  
Laura Ileana Socea ◽  
Stefania Felicia Barbuceanu ◽  
Diana Carolina Ilies ◽  
Mihaela Badea ◽  
...  
Keyword(s):  
Thermal Analysis ◽  
Magnetic Susceptibility ◽  
Metal Complexes ◽  
Daphnia Magna ◽  
Molar Conductivity ◽  
Spectral Studies ◽  
Toxicity Evaluation ◽  
Physico Chemical ◽  
Infrared Spectral ◽  
Chemical Techniques

New copper(II), manganese(II), cobalt(II), nickel(II) and palladium(II) complexes, [Cu(L)(X)(H2O)] [X= OAc- (1), Cl- (3), ClO4- (4)], [M(L)2(H2O)2] [M= Cu2+(2), Mn2+(5)], [M(L)(OAc)(H2O)] [M= Co2+(6), Pd2+(8)], [Ni(L)(OAc)] (7) were synthesized with 2-(5H-dibenzo [a,d][7] annulen-5-ylacetyl)-N-(4-chlorophenyl) hydrazinecarbothioamide (HL). All the metal complexes have been characterized by different physico-chemical techniques like molar conductivity, magnetic susceptibility measurements, electronic and infrared spectral studies, elemental and thermal analysis. The toxicity of newly synthesized compounds was evaluated using the Daphnia magna bioassay.

scholarly journals Synthesis, Characterization, and Biological Activity of Some Transition Metal Complexes Derived from Novel Hydrazone Azo Schiff Base Ligand

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
C. Anitha ◽  
S. Sumathi ◽  
P. Tharmaraj ◽  
C. D. Sheela
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Second Harmonic ◽  
Biological Activities ◽  
Diffusion Method ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Conductivity Measurements ◽  
Tetrahedral Geometry

A series of metal(II) complexes ML where M = VO(II), Co(II), Ni(II), Cu(II), and Zn(II) have been synthesized from azo Schiff base ligand (N′E)-N′-(5-((4-chlorophenyl)diazenyl)-2-hydroxybenzylidene)-2-hydroxybenzohydrazide and characterized on the basis of elemental analyses, electronic, IR, and 1H NMR spectra, magnetic susceptibility and also by aid of scanning electron microscopy (SEM), X-ray powder diffraction, fluorescence spectral studies, and molar conductivity measurements. Conductivity measurements reveal that the complexes are nonelectrolytes. Spectroscopy and other analytical studies reveal distorted square planar geometry for copper, square-pyramidal geometry for oxovanadium, and tetrahedral geometry for other complexes. Redox behavior of the copper(II) complex has been studied with cyclic voltammetry, and the biological activities of the ligand and metal complexes have been studied against several microorganisms by the well diffusion method. All synthesized compounds can serve as potential photoactive materials as indicated from their characteristic fluorescence properties. The second harmonic generation (SHG) efficiency of the ligand was measured and found to be higher than that of urea and KDP. The SEM image of the copper(II) complex implies that the size of the particles is 50 nm.

scholarly journals Synthesis, characterization and biological study of Cu(II) complexes of aminopyridine and (aminomethyl)pyridine Schiff bases

2018 ◽  
Vol 83 (7-8) ◽  
pp. 809-819 ◽  
Author(s):  
Abdullahi Sobola ◽  
Gareth Watkins ◽  
Brecht van
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Biological Study ◽  
Planar Geometry ◽  
Molecular Formula ◽  
Schiff Base Ligands ◽  
Monoclinic System ◽  
1H And 13C Nmr ◽  
Square Planar

The synthesis, characterization and antimicrobial activity determination of some aminopyridine- and (aminomethyl)pyridine?salicylaldimine copper(II) complexes were realized. The ligands, L1?L6, were prepared by condensing salicylaldehyde and o-vanillin with 2- and 3-amino- and (aminomethyl)pyridine, respectively. The complexes were characterized by micro-analytical, electronic, infrared and conductivity data. The structures of the Schiff base ligands were further confirmed from 1H- and 13C-NMR spectral data. This study established that salicylaldimine ligands could coordinate as neutral species via the imine-N and the undeprotonated phenolic-O. The complexes have the molecular formula: [CuLCl], [Cu(LH)2Cl2]?xH2O or [Cu(LH)Cl(H2O)]Cl. The X-ray crystal structure of [CuL6Cl] indicated a square planar geometry with the Schiff base ligand coordinated to the Cu(II) ion as a tridentate monobasic, N2O, ligand. The crystals crystallized in a monoclinic system with P21/c space group. All the ligands and their Cu(II) complexes were screened for their antimicrobial activity against Staphylococcus aureus subsp. aureus ATCC? 6538?*, Bacillus subtillis subsp. spizizenii ATCC? 6633?*, Escherichia coli ATCC? 8739?* and Candida albicans ATCC? 2091?* using agar diffusion and broth dilution techniques. The presence of the methoxyl group enhanced the antimicrobial activity of the salicylaldimine Schiff base ligands.

scholarly journals New 5-bromo-2-hydroxybenzaldehyde S-ethylisothiosemicarbazone and its mixed-ligand Cu(II) complex with imidazole: synthesis, characterization and DFT calculation

2013 ◽  
Vol 11 (11) ◽  
pp. 1844-1851 ◽  
Author(s):  
Reza Takjoo ◽  
Alireza Akbari ◽  
Mehdi Ahmadi ◽  
Hadi Rudbari ◽  
Giuseppe Bruno
Keyword(s):  
Schiff Base ◽  
Analytical Data ◽  
Geometry Optimization ◽  
Schiff Base Complex ◽  
Mixed Ligand ◽  
Planar Geometry ◽  
Base Complex ◽  
Physico Chemical ◽  
Square Planar ◽  
Ft Ir

AbstractA new Schiff base ligand of 5-bromo-2-hydroxybenzaldehyde S-ethyl-isothiosemicarbazone (H2L) was synthesized and its mixed-ligand Cu(II) complex was also prepared by reaction of Cu(NO3)2·3H2O with H2L and imidazole. Their structures were fully characterized by elemental analysis, FT-IR, molar conductivity and UV-Vis methods. The analytical data suggest that the metal, H2L and imidazole ratios in the Schiff base complex are 1:1:1. Single crystal diffraction was also used to better understand the molecular structure of the Cu(II) complex. The results of physico-chemical analyses of the Schiff base complex reveal the coordination geometry around the central atom is square planar. The H2L ligand (NNO donor) is coordinated to the metal center as a tridentate bionegatively agent. Another position of the square planar geometry is occupied by the imidazole ligand. Furthermore, computational studies of the new complex were performed by carrying out DFT calculations. Geometry optimization and natural band analysis of the complex is discussed in further detail.

{1-[2-(Methylamino)ethyliminomethyl]naphthalen-2-olato}thiocyanatocopper(II)

2006 ◽  
Vol 62 (7) ◽  
pp. m1533-m1534 ◽  
Author(s):  
Han-Na Hou
Keyword(s):  
Schiff Base ◽  
Schiff Base Ligand ◽  
Title Compound ◽  
Planar Geometry ◽  
Asymmetric Unit ◽  
Thiocyanate Anion ◽  
Square Planar

The title compound, [Cu(C14H15N2O)(NCS)], is a mononuclear copper(II) complex, with two molecules in the asymmetric unit. The CuII ion is coordinated by one O and two N atoms of a Schiff base ligand, and by one N atom of a thiocyanate anion, forming a square-planar geometry.

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