scholarly journals Unsymmetrical Schiff Base Functionalized as Monobasic Tridentate Ligand on Complexation with Some Transition Metal Ions

2012 ◽  
Vol 9 (2) ◽  
pp. 532-544
Author(s):  
Bibhesh K. Singh ◽  
Narendar Bhojak ◽  
Anant Prakash
Keyword(s):  
Schiff Base ◽  
Transition Metal Ions ◽  
Tridentate Ligand ◽  
Planar Geometry ◽  
Physico Chemical ◽  
Square Planar ◽  
Unsymmetrical Schiff Base ◽  
Mm2 Calculations ◽  
Microbial Potential

Cu(II), Co(II), Ni(II) and Mn(II) complexes of Schiff base derived from 2-aminophenol and pyrrole-2- carbaldehyde have been prepared. The complexes are formed by coordination of N and O atoms of the ligand. Their structures were characterized by physico-chemical and spectroscopic methods. Molecular structure of the complexes has been optimized by MM2 calculations and suggests a tetrahedral/ square planar geometry. The bio-efficacy of the ligand and their complexes has been examined against the growth of bacteriain vitroto evaluate their anti-microbial potential.

scholarly journals Synthesis, Characterization and Investigation of Antimicrobial Activity of a New Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) Phenol and Its Cu(II) and Ni(II) Complexes

2020 ◽  
pp. 30-38
Author(s):  
Musarat Farjana Yesmin ◽  
Farzana Khanm Camellia ◽  
Modina Bashar ◽  
Md. Sajjad Hossain ◽  
Saiyad Nasira ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Schiff Base ◽  
Spectral Studies ◽  
Planar Geometry ◽  
Conductivity Measurements ◽  
Physico Chemical ◽  
Square Planar ◽  
Infrared Spectral ◽  
Chemical Techniques ◽  
And Staphylococcus Aureus

New complexes of Cu (II) and Ni (II) of the Schiff Base, 2-(((2-((4-hydroxybenzylidene) amino)ethyl)imino)methyl) phenol were synthesized and characterized by analytical and  physico-chemical techniques including magnetic susceptibility, conductivity measurements, electronic and IR spectral studies. The infrared spectral studies revealed the tetra-dentate nature of the Schiff base in the complexes. On the basis of all characterizations, square- planar geometry has proposed for all the obtained complexes. The complexes showed moderate antimicrobial activity against Escherichia coli and Staphylococcus aureus.

scholarly journals Mononuclear and Tetranuclear Copper(II) Complexes Bearing Amino Acid Schiff Base Ligands: Structural Characterization and Catalytic Applications

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7301
Author(s):  
Karla-Alejandra López-Gastélum ◽  
Enrique F. Velázquez-Contreras ◽  
Juventino J. García ◽  
Marcos Flores-Alamo ◽  
Gerardo Aguirre ◽  
...  
Keyword(s):  
Schiff Base ◽  
Tridentate Ligand ◽  
Planar Geometry ◽  
X Ray Diffraction ◽  
Schiff Base Ligands ◽  
X Ray ◽  
Square Planar ◽  
Catalytic Applications ◽  
Amino Acid Schiff Base ◽  
Very High

Two new glycine-Schiff base copper(II) complexes were synthesized. Single crystal X-ray diffraction (SCXRD) allowed us to establish the structure of both complexes in the solid state. The glycine-Schiff base copper(II) complex derived from 2′-hydroxy-5′-nitroacetophenone showed a mononuclear hydrated structure, in which the Schiff base acted as a tridentate ligand, and the glycine-Schiff base copper(II) complex derived from 2′-hydroxy-5′-methylacetophenone showed a less common tetranuclear anhydrous metallocyclic structure, in which the Schiff base acted as a tetradentate ligand. In both compounds, copper(II) had a tetracoordinated square planar geometry. The results of vibrational, electronic, and paramagnetic spectroscopies, as well as thermal analysis, were consistent with the crystal structures. Both complexes were evaluated as catalysts in the olefin cyclopropanation by carbene transference, and both led to very high diastereoselectivity (greater than 98%).

scholarly journals New 5-bromo-2-hydroxybenzaldehyde S-ethylisothiosemicarbazone and its mixed-ligand Cu(II) complex with imidazole: synthesis, characterization and DFT calculation

2013 ◽  
Vol 11 (11) ◽  
pp. 1844-1851 ◽  
Author(s):  
Reza Takjoo ◽  
Alireza Akbari ◽  
Mehdi Ahmadi ◽  
Hadi Rudbari ◽  
Giuseppe Bruno
Keyword(s):  
Schiff Base ◽  
Analytical Data ◽  
Geometry Optimization ◽  
Schiff Base Complex ◽  
Mixed Ligand ◽  
Planar Geometry ◽  
Base Complex ◽  
Physico Chemical ◽  
Square Planar ◽  
Ft Ir

AbstractA new Schiff base ligand of 5-bromo-2-hydroxybenzaldehyde S-ethyl-isothiosemicarbazone (H2L) was synthesized and its mixed-ligand Cu(II) complex was also prepared by reaction of Cu(NO3)2·3H2O with H2L and imidazole. Their structures were fully characterized by elemental analysis, FT-IR, molar conductivity and UV-Vis methods. The analytical data suggest that the metal, H2L and imidazole ratios in the Schiff base complex are 1:1:1. Single crystal diffraction was also used to better understand the molecular structure of the Cu(II) complex. The results of physico-chemical analyses of the Schiff base complex reveal the coordination geometry around the central atom is square planar. The H2L ligand (NNO donor) is coordinated to the metal center as a tridentate bionegatively agent. Another position of the square planar geometry is occupied by the imidazole ligand. Furthermore, computational studies of the new complex were performed by carrying out DFT calculations. Geometry optimization and natural band analysis of the complex is discussed in further detail.

Synthesis, Characterization and in vitro Biological Evaluation of a New Schiff Base Derived from Drug and its Complexes with Transition Metal Ions

2018 ◽  
Vol 69 (7) ◽  
pp. 1678-1681
Author(s):  
Amina Mumtaz ◽  
Tariq Mahmud ◽  
M. R. J. Elsegood ◽  
G. W. Weaver
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Free Ligand ◽  
Transition Metal Ions ◽  
Biological Evaluation ◽  
Pyridoxal Hydrochloride

New series of copper (II), cobalt (II), zinc (II), nickel (II), manganese (II), iron (II) complexes of a novel Schiff base were prepared by the condensation of sulphadizine and pyridoxal hydrochloride. The ligand and metal complexes were characterized by utilizing different instrumental procedures like microanalysis, thermogravimetric examination and spectroscopy. The integrated ligand and transition metal complexes were screened against various bacteria and fungus. The studies demonstrated the enhanced activity of metal complexes against reported microbes when compared with free ligand.

New Platinum (II) Ternary Complexes of Formamidine and Pyrophosphate: Synthesis, Characterization and DFT Calculations and In vitro Cytotoxicity

2020 ◽  
Vol 23 (7) ◽  
pp. 611-623
Author(s):  
Ahmed A. Soliman ◽  
Fawzy A. Attaby ◽  
Othman I. Alajrawy ◽  
Azza A.A. Abou-hussein ◽  
Wolfgang Linert
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Theoretical Calculations ◽  
Thermal Analyses ◽  
Cancer Cell Line ◽  
Cellular Growth ◽  
Planar Geometry ◽  
Square Planar ◽  
Vis Spectroscopy

Aim and Objective: Platinum (II) and platinum (IV) of pyrophosphate complexes have been prepared and characterized to discover their potential as antitumor drugs. This study was conducted to prepare and characterize new ternary platinum (II) complexes with formamidine and pyrophosphate as an antitumor candidate. Materials and Methods: The complexes have been characterized by mass, infrared, UV-Vis. spectroscopy, elemental analysis, magnetic susceptibility, thermal analyses, and theoretical calculations. They have been tested for their cytotoxicity, which was carried out using the fastcolorimetric assay for cellular growth and survival against MCF-7 (breast cancer cell line), HCT- 116 (colon carcinoma cell line), and HepG-2 (hepatocellular cancer cell line). Results: All complexes are diamagnetic, and the electronic spectral data displayed the bands due to square planar Pt(II) complexes. The optimized complexes structures (1-4) indicated a distorted square planar geometry where O-Pt-O and N-Pt-N bond angles were 82.04°-96.44°, respectively. Conclusion: The complexes showed noticeable cytotoxicity and are considered as promising antitumor candidates for further applications.

{1-[2-(Methylamino)ethyliminomethyl]naphthalen-2-olato}thiocyanatocopper(II)

2006 ◽  
Vol 62 (7) ◽  
pp. m1533-m1534 ◽  
Author(s):  
Han-Na Hou
Keyword(s):  
Schiff Base ◽  
Schiff Base Ligand ◽  
Title Compound ◽  
Planar Geometry ◽  
Asymmetric Unit ◽  
Thiocyanate Anion ◽  
Square Planar

The title compound, [Cu(C14H15N2O)(NCS)], is a mononuclear copper(II) complex, with two molecules in the asymmetric unit. The CuII ion is coordinated by one O and two N atoms of a Schiff base ligand, and by one N atom of a thiocyanate anion, forming a square-planar geometry.

Bis[6-(cyclopentyliminomethyl)-2-methoxyphenolato]nickel(II)

2007 ◽  
Vol 63 (3) ◽  
pp. m704-m705 ◽  
Author(s):  
Xiao-Fan Zhao
Keyword(s):  
Schiff Base ◽  
Planar Geometry ◽  
Inversion Symmetry ◽  
Schiff Base Ligands ◽  
Square Planar

The molecule of the title mononuclear compound, [Ni(C13H16NO2)2], possesses crystallographic inversion symmetry. The Ni atom, lying on the inversion centre, is four-coordinated in a square-planar geometry by two Schiff base ligands.

scholarly journals Synthesis, characterization and antimicrobial Studies of complexes of some metal ions with 5(2-hydroxy benzylidine) -2-thio ether -1, 3, 4-thiadiazole

2010 ◽  
Vol 7 (1) ◽  
pp. 585-592
Author(s):  
Baghdad Science Journal
Keyword(s):  
Iron Complex ◽  
Octahedral Geometry ◽  
Planar Geometry ◽  
In Vitro Tests ◽  
Conductivity Measurements ◽  
Antimicrobial Studies ◽  
Square Planar ◽  
Escherchia Coli ◽  
Complex Display

A new series of Fe (III) , Co (II) , Ni (II) and Cu (II) complexes of the Schiff base, 5 (2-hydroxy benzylidine) -2-thio ether -1, 3, 4-thiadiazole were prepared and characterized .The imine behaves as a bidentate. The nature of bonding and the stereochemistry of the complexes were deduced from metal analyses, infrared, electronic spectra,magnetic susceptibility and conductivity measurements, an octahedral geometry was suggested for all complexes except the copper complex has a square planar geometry .preliminary in vitro tests for antimicrobial activity show that all the prepared compounds except iron complex display good activity to gram positive Staphelococcus aures and gram negative Escherchia coli.

scholarly journals Nickel(II)-Based Building Blocks with Schiff Base Derivatives: Experimental Insights and DFT Calculations

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5316
Author(s):  
Néstor Novoa ◽  
Carolina Manzur ◽  
Thierry Roisnel ◽  
Samia Kahlal ◽  
Jean-Yves Saillard ◽  
...  
Keyword(s):  
Schiff Base ◽  
General Formula ◽  
Metal Ion ◽  
Density Functional ◽  
Building Blocks ◽  
Switching Behavior ◽  
Planar Geometry ◽  
Centrosymmetric Dimer ◽  
Square Planar ◽  
Tridentate Schiff Base

We have recently reported a series of neutral square planar tridentate Schiff base (L) complexes of the general formula [(L)M(py)], showing relatively high first-order hyperpolarizabilities and NLO redox switching behavior. In the present study, new members of this family of compounds have been prepared with the objective to investigate their potential as building blocks in the on-demand construction of D-π-A push–pull systems. Namely, ternary nickel(II) building blocks of general formula [(LA/D)Ni(4-pyX)] (4–7), where LA/D stands for an electron accepting or donating dianionic O,N,O-tridentate Schiff base ligand resulting from the monocondensation of 2-aminophenol or its 4-substituted nitro derivative and β-diketones R-C(=O)CH2C(=O)CH3 (R = methyl, anisyl, ferrocenyl), and 4-pyX is 4-iodopyridine or 4-ethynylpyridine, were synthesized and isolated in 60–78% yields. Unexpectedly, the Sonogashira cross-coupling reaction between the 4-iodopyridine derivative 6 and 4-ethynylpyridine led to the formation of the bis(4-pyridyl) acetylene bridged centrosymmetric dimer [{(LD)Ni}2(µ2-py-C≡C-py)] (8). Complexes 4–8 were characterized by elemental analysis, FT-IR and NMR spectroscopy, single crystal X-ray diffraction and computational methods. In each compound, the four-coordinate Ni(II) metal ion adopts a square planar geometry with two nitrogen and two oxygen atoms as donors occupying trans positions. In 8, the Ni…Ni separation is of 13.62(14) Å. Experimental results were proved and explained theoretically exploiting Density Functional Theory calculations.

scholarly journals Crystal structure of {bis[2-(3,5-dimethylpyrazol-1-yl-κN2)ethyl]amine-κN}chloridoplatinum(II) chloride dihydrate

2015 ◽  
Vol 71 (4) ◽  
pp. m98-m99
Author(s):  
María de los Angeles Mendoza ◽  
Sylvain Bernès ◽  
Guillermo Mendoza-Díaz
Keyword(s):  
Tridentate Ligand ◽  
Planar Geometry ◽  
Acta Cryst ◽  
Complex Molecules ◽  
Chloride Dihydrate ◽  
Square Planar ◽  
Unit Form ◽  
Chloride Ligand ◽  
Amine Groups ◽  
Ethyl Amine

The title complex, [PtCl(C14H23N5)]Cl·2H2O, is isomorphous with the PdIIcompound characterized previously [Mendoza, Bernès & Mendoza-Díaz (2006).Acta Cryst. E62, m2934–m2936]. The angle between pyrazole mean planes in the main ligand is 88.3 (4)°, similar to that observed in the PdIIanalogue [87.62 (11)°]. This tridentate ligand adopts a conformation approximating a twofold symmetry, allowing its coordination to the metal atom, together with a chloride ligand, in an almost perfect square-planar geometry. A chloride anion and two water molecules in the asymmetric unit form a hydrogen-bonded network connected to the complex molecules in the crystalviathe NH amine groups, forming chains along [100].

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