‘Research on Clinical Significance of Blood groups on Bleeding time and Clotting Time and its Association with Diseases; An Advanced Study’

Introduction: Blood grouping, bleeding time (BT) and clotting time (CT) are important hematological parameters investigated before any surgical procedure. The association of blood groups with many diseases are established, such as epistaxis with blood group “O”. This study aimed to assess the relationship of BT and CT among different blood groups and to find any gender difference in these parameters. Materials and methods: A cross-sectional observational study was conducted among healthy medical students. Blood grouping was done by agglutination method, BT by Duke’s method, and CT by capillary tube method. Mean bleeding and clotting times (seconds) were compared among groups. Results: The study was completed in 351 students (160 males, 191 females), with age ranging from 19-23 years. Both BT and CT values were highest in the blood type O, BT was lowest in type B, and CT was lowest in type AB, although the differences were statistically not significant (p>0.15). Females had higher values of BT as well as CT than males (p values <0.001). A very highly significant correlation between the bleeding and clotting times was also noticed (Pearson’s correlation coefficient, P = 0.495, p<0.001). Conclusions: The study hinted a tendency for higher risk for hemorrhagic condition and lower risk for thrombotic event in blood group O compared to groups A, B or AB. Multicentric study including larger population with the emphasis on finding plasma vWF level may be helpful to verify findings, identify the risk groups, and take prior preventive measures.

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BLEEDING TIME AND CLOTTING TIME IN DIFFERENT BLOOD GROUPS- A CROSS SECTIONAL STUDY

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2019/398 ◽

2019 ◽

Vol 8 (22) ◽

pp. 1813-1815

Author(s):

Laishram Leimahanbi Chanu ◽

Rajkumar Bikramjit Singh ◽

Bishwalata Rajkumari ◽

Sumpi Rosemary Anal

Keyword(s):

Bleeding Time ◽

Cross Sectional Study ◽

Blood Groups ◽

Sectional Study ◽

Clotting Time ◽

Cross Sectional

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Relationship Between Bleeding Time And Clotting Time Among Gender Difference And Varying Blood Groups In UG Medical Student

IOSR Journal of Dental and Medical Sciences ◽

10.9790/0853-1064043 ◽

2013 ◽

Vol 10 (6) ◽

pp. 40-43 ◽

Cited By ~ 1

Author(s):

Sasekala M ◽

Keyword(s):

Medical Student ◽

Gender Difference ◽

Bleeding Time ◽

Blood Groups ◽

Clotting Time

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Correlation of blood groups, clotting time and bleeding time in male and female students; an observational study.

Pakistan Journal of Pharmaceutical Research ◽

10.22200/pjpr.20162121-126 ◽

2016 ◽

Vol 2 (2) ◽

pp. 121 ◽

Cited By ~ 1

Author(s):

Ambreen Aleem ◽

Muqeet Wahid

Keyword(s):

Blood Group ◽

Bleeding Time ◽

Capillary Tube ◽

Gastrointestinal Diseases ◽

Blood Groups ◽

Essential Factor ◽

Clotting Time ◽

The Difference ◽

Gender Based ◽

B Blood Group

ABSTRACT:Stoppage of bleeding from damaged blood vessels is hemostasis, an essential factor to be checked before any surgical process. Hence blood test is a routine test for hospital prior to surgeries. The aim of this study is to assess the blood groups distribution and to check gender based relationship among blood groups, bleeding and clotting time. The study was conducted in the department of pharmacy, BZU. The available detail reports of 122 students of 1st year of Pharm.D were analyzed in aspects of age, sex, blood groups, bleeding time and clotting time. The blood group were determined with the standard antisera, Duke Method and Capillary tube method were used to find out bleeding time and clotting time respectively. Finally all the parameters were compared and analyzed statistically. In the present study it is found that B blood group is more prevalent in both the sexes than O, A and AB. Clotting time is found to be significantly higher in O and B blood groups in females and males respectively, whereas Bleeding time was found to be prolonged in maximum number of group AB in females and blood group O in males but the difference was statistically insignificant. In females, bleeding and clotting time are slightly on higher side than in males, may be because of hormonal differences. Various cardiovascular and gastrointestinal diseases are associated with the blood groups, so people can take preventive measures according to their blood groups.

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