scholarly journals Correlation of blood groups, clotting time and bleeding time in male and female students; an observational study.

2016 ◽  
Vol 2 (2) ◽  
pp. 121 ◽  
Author(s):  
Ambreen Aleem ◽  
Muqeet Wahid

ABSTRACT:Stoppage of bleeding from damaged blood vessels is hemostasis, an essential factor to be checked before any surgical process. Hence blood test is a routine test for hospital prior to surgeries. The aim of this study is to assess the blood groups distribution and to check gender based relationship among blood groups, bleeding and clotting time. The study was conducted in the department of pharmacy, BZU. The available detail reports of 122 students of 1st year of Pharm.D were analyzed in aspects of age, sex, blood groups, bleeding time and clotting time. The blood group were determined with the standard antisera, Duke Method and Capillary tube method were used to find out bleeding time and clotting time respectively. Finally all the parameters were compared and analyzed statistically. In the present study it is found that B blood group is more prevalent in both the sexes than O, A and AB. Clotting time is found to be significantly higher in O and B blood groups in females and males respectively, whereas Bleeding time was found to be prolonged in maximum number of group AB in females and blood group O in males but the difference was statistically insignificant. In females, bleeding and clotting time are slightly on higher side than in males, may be because of hormonal differences. Various cardiovascular and gastrointestinal diseases are associated with the blood groups, so people can take preventive measures according to their blood groups.

2018 ◽  
Vol 5 (2) ◽  
pp. 3553-3556
Author(s):  
Masarat Nazeer ◽  
Shaugfta Aara ◽  
Nadeema Rafiq

Background: Evaluation of blood groups, bleeding and clotting time are the most important and initial hematological parameters done routinely and especially before any surgical procedure. Researches indicate that various gastrointestinal diseases like ulcers, cancers, UTIs, cardiovascular disorder , diabetes mellitus as well as thrombosis, epistaxis etc. are associated with ABO blood group system. Hemostatic parameters like BT and CT also vary in different blood groups. Materials and methods: The available data of 400 students of 1st year of mbbs, bds and para medical courses was analyzed in every required  aspects i.e. sex, age, ABO and Rh blood groups, bleeding and clotting times. The standard antisera  (A, B, & D) was used to determine the blood group, Duke’s Method and Capillary tube method were used to find out bleeding and clotting time respectively. Finally, all the parameters were compared and analyzed statistically. Results: Blood group B (44.5%) was the most common blood group in both genders followed by O (30.5%), A (21%), and AB (4%). Bleeding time was found to be prolonged >4 min in maximum number of group O (53%) followed by group A (26.4%), group B (14.2%), and then group AB(6.1%) but the difference was statistically significant (p = 0.00005). Similarly clotting time was >6 min in group O(54.5%) followed by group B=A(18.1%), group least in AB (9%),  but the difference was statistically significant (p = 0.19). Gender-wise bleeding time was more prolonged in females (67.3%) than males (32.6%) but the difference was statistically insignificant (p = 0.07), similarly clotting time too was prolonged more in females (81%)than males (18.2%) but again the difference was statistically significant (p = 0.04). Conclusion : In our study, blood group B predominated followed by O, A, and AB. Bleeding time was prolonged >4 min in blood group O followed by A,B, and  AB whereas clotting time was prolonged >6 min in blood group O followed by A=B and then AB. Gender-wise bleeding and clotting time were higher in females than males. Various blood related disorders, cardiovascular and gastrointestinal diseases are associated with blood groups,  so people can take preventive measures according to their blood groups.


2020 ◽  
Vol 1 (2) ◽  
pp. 19-23
Author(s):  
Seerina Adhikari Manandhar ◽  
Mrigendra Amatya

Introduction: Blood grouping, bleeding time (BT) and clotting time (CT) are important hematological parameters investigated before any surgical procedure. The association of blood groups with many diseases are established, such as epistaxis with blood group “O”. This study aimed to assess the relationship of BT and CT among different blood groups and to find any gender difference in these parameters. Materials and methods: A cross-sectional observational study was conducted among healthy medical students. Blood grouping was done by agglutination method, BT by Duke’s method, and CT by capillary tube method. Mean bleeding and clotting times (seconds) were compared among groups. Results: The study was completed in 351 students (160 males, 191 females), with age ranging from 19-23 years. Both BT and CT values were highest in the blood type O, BT was lowest in type B, and CT was lowest in type AB, although the differences were statistically not significant (p>0.15). Females had higher values of BT as well as CT than males (p values <0.001). A very highly significant correlation between the bleeding and clotting times was also noticed (Pearson’s correlation coefficient, P = 0.495, p<0.001). Conclusions: The study hinted a tendency for higher risk for hemorrhagic condition and lower risk for thrombotic event in blood group O compared to groups A, B or AB. Multicentric study including larger population with the emphasis on finding plasma vWF level may be helpful to verify findings, identify the risk groups, and take prior preventive measures.


Author(s):  
Reeta Baishya ◽  
Raj Sarkar ◽  
Barasha Barman

 Background: Blood group and its relation to bleeding time (BT) and clotting time (CT) is important in conditions like epistaxis, thrombosis, and surgery. Earlier studies depicted O group having prolonged BT and CT. The aim of this study was to assess the relationship of BT and CT with ABO groups.Methods: This cross-sectional study was conducted in the department of physiology, Gauhati medical college. The study included 154 students. Blood grouping was determined with the standard antiserum; BT and CT were estimated by the duke method and slide method, respectively. Blood group and its relation to BT, CT were analyzed by Chi-square analysis.Results: Blood group O (42.2%) was predominant in both genders followed by B (31.8%), A (21%), AB (4.5%). CT was found to be more than 6 minutes in group O (31.57%) followed by group AB (26.31%), A and B (21.05%). The difference was statistically significant (p = 0.02). BT was found to be more than 4 minutes in group O (82.35%) followed by A (11.76%), B (5.88%), and AB (0%). That was statistically significant (p = 0.01). CT was more than 6 minutes in 57.89% in females as compared to 42.10% in males, variation was statistically significant (p = 0.01). BT was more than 4 minutes in 58.82% females as compared to 41.17% in males. The variation was statistically significant (p = 0.03).Conclusions: In present study blood group O was more common followed by B, A, and AB. CT and BT were prolonged in O group. BT and CT were more in females than males.


2021 ◽  
Vol 15 (10) ◽  
pp. 2776-2778
Author(s):  
Sobia Siddique ◽  
Syed Muhammad Razi Zaidi ◽  
Shahida Maqbool ◽  
Madiha Insha ◽  
Muhammad Abul Hasan Ali ◽  
...  

Objective: To assess any association of blood groups with oral submucous fibrosis and if any of the blood group is related with an increased risk for oral submucous fibrosis. Study Design: Comparative study Place and Duration of Study: Department Of Oral Pathology, Fatima Jinnah Dental College & Hospital Karachi, Pakistan from Jan to Dec 2018. Patients and Methods: Total 100 patients were enrolled in the study in which half were cases where oral sub mucous fibrosis had been diagnosed clinically while remaining half were the controls that were involved in the habit of using tobacco/nuts but had no oral pre malignant lesion. For investigation of blood, samples of blood were taken from both the groups. Odd ration and chi-square test was used to analyze data. A p-value of <0.05 was considered statistically significant. Results: Majority of the individuals in experimental group had “B” blood group followed by “O” “AB” and “A” blood groups. Conclusion: This study showed that ABO blood groups have considerable relation with oral submucous fibrosis. Individuals having “B” blood group had 2.18 times increased tendency of having oral submucous fibrosis in contrast with patients who belong to any other blood group. Keywords: ABO blood group system, Oral Submucous fibrosis, Oral lesions, Oral Squamous Cell Carcinoma


1970 ◽  
Vol 1 (4) ◽  
pp. 135-140 ◽  
Author(s):  
Bedanta Roy ◽  
Indrajit Banerjee ◽  
Brijesh Sathian ◽  
Monami Mondal ◽  
Chhanchu Gopal Saha

Background Blood group, Bleeding Time and Clotting time are clinically useful tests, extensively used during blood transfusion, platelet disorders and a variety of forms of treatment in hospitals. The objective of our study was to assess the country wise distribution of blood groups and to compare the country wise bleeding time and clotting time with respect to blood group. Material and Methods This Observational Study has been performed at Manipal College of Medical Sciences, during the period of 1st May 2010 to 31st August–2011. The study was carried out on the undergraduate medical students of Basic sciences and included assessment of Bleeding time, Clotting time and Blood grouping by standard procedures. Results 261 medical students participated in the study. Among the Nepalese students, 30.5% had blood group A, 28.9% B, 5.5% AB and remaining 35.2% O. among the Indian students, 22.8% were blood group A, 45.7% B, 7.6% AB and 23.9% O. In Sri Lankan students, 22% had blood group A, 19.5% B, 4.9% AB, and 53.7% blood group O. Among Nepalese students, BT was higher in blood group A (163.85 seconds) as compared to Indians (154.29Sec) and Sri Lankans (133.33 sec). Nepalese students with AB blood group had higher BT (171.43 sec). Indian students with blood group A had comparatively higher clotting time (328.57 sec) followed by Nepali (276.15 sec) and then Sri Lankan students (270 sec). Girls are 4.432 times more prone for bleeding time greater than 4 minutes and 2.453 times for clotting time value above 6 minutes as compared to males. Conclusion Our study suggests that O blood group is predominant in Nepalese students while Blood group B was the most common blood group in the Indian students. We found higher BT and CT in females, which are more prominent in Indians, so this gender disparity is an additional risk factor for them. Health Ministries of respective countries have to improve the proper health care policies required for prevention and management of blood group diseases, bleeding time and clotting time related disorders like Hypoprothrombinemia and Thrombocytopenia.http://dx.doi.org/10.3126/nje.v1i4.5755 Nepal Journal of Epidemiology 2011;1(4):135-140


2021 ◽  
Vol 17 (3) ◽  
pp. 265-278
Author(s):  
Kalipada Kar ◽  
Sujata Kar

Introduction: Blood group antigens and body mass index of human are gaining importance for many diseases. Some attempts were reported to find any relationship between BMI and Blood groups with some contradictions. The possible association between BMI and blood groups of Nepalese and Indian medical students is yet to be established. Methods: Blood groups, ABO and Rh systems and body mass index (BMI) of participants, medical students of Nepalese and Indian origin were determined and analyzed statistically. Results: The distribution frequencies of 10.56%, 17.08%, 3.06%, and 20.28% females and 9.03%, 16.39%, 3.61% and 20.0% males of both the countries were present in A, B, AB and O blood groups, respectively. Rh-negative participants were predominantly present in O blood group. The observed frequencies of participants with different BMI group were distributed as 56.11%, 24.72%, 10.69% and 8.47% in Normal, Overweight, Underweight and Obese groups, respectively. Underweight participants were prevalent in O group and in females. The difference between the distribution of Nepalese females and males with Normal BMI was found significant in A and O. A distribution pattern of B>O>A>AB was observed for Overweight group. The occurrence of Obese is few folds higher among Indian participants than Nepalese and prevalent in males. Obese participants were found more associated with B and O blood group. Conclusions: Participants with A were more prevalent among Nepalese in respect to Indian. Rh-negative participants were distributed as 1.67% and 5.0% in Nepalese and Indians, respectively and predominantly present in O (4.44%) and are more prevalent in Indian males. In Normal BMI Nepalese were significantly more as compared to Indians. In the Underweight group females were significantly more prevalent as compared to males and found maximally associated with O blood group and most of them are Nepalese. In Overweight group males were more than females. Participants with obesity were mostly present in B and O blood group and most of them are Indian.


2019 ◽  
Vol 41 (3) ◽  
pp. 74-77
Author(s):  
Barun Mahat ◽  
Lava Shrestha ◽  
Shailesh Adhikari ◽  
Bikalp Thapa ◽  
Prakesh Limbu ◽  
...  

Introduction Knowing a person’s blood type is not only important in transfusion medicine and forensic medicine but is also useful for predicting a person’s characteristics including intelligence, knowledge, skill and behavior. It is recognized that intelligence, knowledge and skill are assessed by performance in examination. The objective of this study was to determine distribution of blood groups among students and its association with their academic performance. MethodsThis was an analytical study that was conducted among the medical students of Nepalese Army Institutes of Health Sciences (NAIHS) in Department of Clinical Physiology from June 2014 to April 2019. This study was conducted among 738 students by using convenient sampling method. Blood group was determined on the basis of agglutination reaction. Academic performance of students was assessed by the marks obtained by them in annual final examination. ResultsBlood group O was the most prevalent at 33.5%, followed by B at 29.5%, A at 29% and AB at 8%. Distribution of Rh positive and Rh negative were 96.6% and 3.4% respectively. The mean scores obtained in final university examination were highest in blood group A (62.9%) and lowest in blood group AB (60.3%) but the difference between different blood groups was not statistically significant. ConclusionBlood group O was the most common blood group. Rh positive was present in 96.6%. Though mean score was highest in blood group A, significant association between blood groups and academic performance was not seen in our study.


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