scholarly journals Variation of bleeding time and clotting time in the ABO blood groups

2020 ◽  
Vol 1 (2) ◽  
pp. 19-23
Author(s):  
Seerina Adhikari Manandhar ◽  
Mrigendra Amatya
Keyword(s):  
Blood Group ◽  
Bleeding Time ◽  
Capillary Tube ◽  
Hematological Parameters ◽  
Thrombotic Event ◽  
Blood Groups ◽  
Blood Type ◽  
Clotting Time ◽  
Multicentric Study ◽  
Blood Grouping

Introduction: Blood grouping, bleeding time (BT) and clotting time (CT) are important hematological parameters investigated before any surgical procedure. The association of blood groups with many diseases are established, such as epistaxis with blood group “O”. This study aimed to assess the relationship of BT and CT among different blood groups and to find any gender difference in these parameters. Materials and methods: A cross-sectional observational study was conducted among healthy medical students. Blood grouping was done by agglutination method, BT by Duke’s method, and CT by capillary tube method. Mean bleeding and clotting times (seconds) were compared among groups. Results: The study was completed in 351 students (160 males, 191 females), with age ranging from 19-23 years. Both BT and CT values were highest in the blood type O, BT was lowest in type B, and CT was lowest in type AB, although the differences were statistically not significant (p>0.15). Females had higher values of BT as well as CT than males (p values <0.001). A very highly significant correlation between the bleeding and clotting times was also noticed (Pearson’s correlation coefficient, P = 0.495, p<0.001). Conclusions: The study hinted a tendency for higher risk for hemorrhagic condition and lower risk for thrombotic event in blood group O compared to groups A, B or AB. Multicentric study including larger population with the emphasis on finding plasma vWF level may be helpful to verify findings, identify the risk groups, and take prior preventive measures.

scholarly journals Blood Groups, BT and CT in Medical and Para Medical Students-Gender Based Distribution and Their Relation. An Observational Study.

2018 ◽  
Vol 5 (2) ◽  
pp. 3553-3556
Author(s):  
Masarat Nazeer ◽  
Shaugfta Aara ◽  
Nadeema Rafiq
Keyword(s):  
Blood Group ◽  
Bleeding Time ◽  
Capillary Tube ◽  
Hematological Parameters ◽  
Gastrointestinal Diseases ◽  
Blood Groups ◽  
Blood Group System ◽  
Clotting Time ◽  
The Difference ◽  
Group B

Background: Evaluation of blood groups, bleeding and clotting time are the most important and initial hematological parameters done routinely and especially before any surgical procedure. Researches indicate that various gastrointestinal diseases like ulcers, cancers, UTIs, cardiovascular disorder , diabetes mellitus as well as thrombosis, epistaxis etc. are associated with ABO blood group system. Hemostatic parameters like BT and CT also vary in different blood groups. Materials and methods: The available data of 400 students of 1st year of mbbs, bds and para medical courses was analyzed in every required  aspects i.e. sex, age, ABO and Rh blood groups, bleeding and clotting times. The standard antisera  (A, B, & D) was used to determine the blood group, Duke’s Method and Capillary tube method were used to find out bleeding and clotting time respectively. Finally, all the parameters were compared and analyzed statistically. Results: Blood group B (44.5%) was the most common blood group in both genders followed by O (30.5%), A (21%), and AB (4%). Bleeding time was found to be prolonged >4 min in maximum number of group O (53%) followed by group A (26.4%), group B (14.2%), and then group AB(6.1%) but the difference was statistically significant (p = 0.00005). Similarly clotting time was >6 min in group O(54.5%) followed by group B=A(18.1%), group least in AB (9%),  but the difference was statistically significant (p = 0.19). Gender-wise bleeding time was more prolonged in females (67.3%) than males (32.6%) but the difference was statistically insignificant (p = 0.07), similarly clotting time too was prolonged more in females (81%)than males (18.2%) but again the difference was statistically significant (p = 0.04). Conclusion : In our study, blood group B predominated followed by O, A, and AB. Bleeding time was prolonged >4 min in blood group O followed by A,B, and  AB whereas clotting time was prolonged >6 min in blood group O followed by A=B and then AB. Gender-wise bleeding and clotting time were higher in females than males. Various blood related disorders, cardiovascular and gastrointestinal diseases are associated with blood groups,  so people can take preventive measures according to their blood groups.

scholarly journals Correlation of blood groups, clotting time and bleeding time in male and female students; an observational study.

2016 ◽  
Vol 2 (2) ◽  
pp. 121 ◽  
Author(s):  
Ambreen Aleem ◽  
Muqeet Wahid
Keyword(s):  
Blood Group ◽  
Bleeding Time ◽  
Capillary Tube ◽  
Gastrointestinal Diseases ◽  
Blood Groups ◽  
Essential Factor ◽  
Clotting Time ◽  
The Difference ◽  
Gender Based ◽  
B Blood Group

ABSTRACT:Stoppage of bleeding from damaged blood vessels is hemostasis, an essential factor to be checked before any surgical process. Hence blood test is a routine test for hospital prior to surgeries. The aim of this study is to assess the blood groups distribution and to check gender based relationship among blood groups, bleeding and clotting time. The study was conducted in the department of pharmacy, BZU. The available detail reports of 122 students of 1st year of Pharm.D were analyzed in aspects of age, sex, blood groups, bleeding time and clotting time. The blood group were determined with the standard antisera, Duke Method and Capillary tube method were used to find out bleeding time and clotting time respectively. Finally all the parameters were compared and analyzed statistically. In the present study it is found that B blood group is more prevalent in both the sexes than O, A and AB. Clotting time is found to be significantly higher in O and B blood groups in females and males respectively, whereas Bleeding time was found to be prolonged in maximum number of group AB in females and blood group O in males but the difference was statistically insignificant. In females, bleeding and clotting time are slightly on higher side than in males, may be because of hormonal differences. Various cardiovascular and gastrointestinal diseases are associated with the blood groups, so people can take preventive measures according to their blood groups.

scholarly journals Impact of blood group in dengue: a study

2019 ◽  
Vol 6 (5) ◽  
pp. 1647
Author(s):  
Anagha A. Joshi ◽  
Fazeela Muneer ◽  
Gayathri B. R. ◽  
Divyashree B. N.
Keyword(s):  
Blood Group ◽  
Hematological Parameters ◽  
Blood Groups ◽  
The Other ◽  
Severe Thrombocytopenia ◽  
Abo Blood Groups ◽  
Male Predominance ◽  
Close Supervision ◽  
Age Range ◽  
Blood Grouping

Background: Dengue can result in high mortality. Several studies have shown an association of blood groups with the severity of dengue. In our study we attempt to associate the prevalence of blood groups with the known hematological prognosticators and thus derive its impact on the severity of dengue. We aim to study the patterns and prevalence of different ABO blood groups in dengue fever.Methods: A total of 100 serologically proven dengue cases over a month’s period in November 2016 were recruited for our study. Their relevant hematological data (obtained by automated haematology analyser and peripheral smears) and blood grouping results were recorded and analyzed.Results: The age range was 5 months to 65 years with a slight male predominance. Analysis of the blood group patterns showed prevalence of O group (42%) followed by A and B group (27% each). B group was more prevalent in children (34%) and females (31%) with dengue.The patients with B group showed increased derangement in hematological parameters namely higher number of cases with B group showed rise in haematocrit (59%), an increased number of cases with leucopenia (56%), higher proportion of cases with lymphocytosis (45%) and  severe thrombocytopenia  (74%) when compared to the other blood groups.Conclusions: Our study shows that blood groups can impact severity of dengue and that B group is a risk factor for severity hence, such individuals warrant close supervision especially in the presence of other risk factors.

scholarly journals DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

1969 ◽  
Vol 3 (2) ◽  
pp. 318-322
Author(s):  
MUHAMMAD KHALID ◽  
NAILA ASLAM ◽  
MUHAMMAD SIYAR ◽  
RASHID AHMAD
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Local Community ◽  
Healthy Adult ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Group B ◽  
Abo Blood Grouping ◽  
Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

scholarly journals Prevalence of ABO blood groups in patients with haematological malignancies: a retrospective study

2020 ◽  
Vol 8 (1) ◽  
pp. 13-17
Author(s):  
Ashwin Mathew ◽  
Kirana Pailoor, ◽  
Konchady Deepthi ◽  
Suresh Shenoy
Keyword(s):  
Sex Ratio ◽  
Blood Group ◽  
Haematological Malignancy ◽  
Geographical Location ◽  
Blood Groups ◽  
Blood Type ◽  
Haematological Malignancies ◽  
Abo Blood Groups ◽  
College Hospital ◽  
And Gender

Background: The pattern and distribution of Haematological malignancies vary depending on age, sex and geographical location. Studies on the association between Haematological cancers and ABO blood types have been largely conflicting. The objective of our study was to determine the distribution of ABO blood groups among patients with Haematological malignancies and to correlate with age and gender. Materials and Methods: This was a chart based observational descriptive study involving the review of records of 85 patients with various Haematological malignancies in Father Muller Medical College Hospital for a period of two years from July 2017- June 2019. Age, gender, malignant condition, ABO and Rh blood group were collected for each case. Data was analyzed statistically by frequency and percentage. Results: The peak age incidence for various Haematological malignancies was in the fifth and sixth decades of life with a mean age of 47.The male to female sex ratio was almost 1:1. Majority of the patients were of the O blood group and an association of O blood group with various hematological malignancies with male preponderance was noted. Altogether, Leukemias were the most common Haematological malignancy observed in this study. Conclusion: The distribution, age and sex ratio of Haematological malignancies in our study was comparable to those reported by other authors with Acute Myeloid Leukemia (AML) being the most common Haematological malignancy in our environment. There was no significant association between Haematological cancers and ABO blood type of the patients, but probably individuals with O Rh positive blood group are more prone to

scholarly journals The Clinical and Hematological changes in Rabbits exposed to Melia azedarach fruits under experimental conditions

2015 ◽  
Vol 1 (1) ◽  
pp. 12 ◽  
Author(s):  
AL- Zubaedi Raad Mahmood
Keyword(s):  
Body Weight ◽  
Body Temperature ◽  
Bleeding Time ◽  
Hematological Parameters ◽  
The Body ◽  
Melia Azedarach ◽  
Control Group ◽  
Clotting Time ◽  
Experimental Conditions ◽  
Hb Concentration

The study was conducted on 10 local breed rabbits, of 1-2 years age, of 1- 1.5 kg body weight. They were feed concentrated and green food, and left ad libitum for water, and kept in room of 20- 25 oC. The animals divided into two groups of 5 each. First as treated group received the plant in powder form mixed with the food at a dose rate of 5 g/ animal / day for three weeks , while the second left without exposure as a control group .The main dependent parameters in the study were , clinical parameters ( body temperature , heartbeat , respiratory rate, body weight , in addition to monitor any abnormal signs appear on the animals . While the main hematological parameters were included , RBC count , WBC count , Hb concentration,PCV percentage , Red cell indices , Bleeding time and Clotting time. The body temperature, respiratory rates, heart rate were increased .The body weight decreased .The bleeding time and clotting time were prolonged. The erythrocyte count, Hb concentration, and MCV values were decreased; PCV and MCHC did not showed any significant changes. The MCH increased. The total leucocytes count and the basophiles percentage did not showed any significant changes. The Heterophils and monocytes percentage increased .The lymphocytic and Eosinophil percentage were decreased during the study.

scholarly journals Blood Group Distribution and Its Relationship with Bleeding Time and Clotting Time: A Medical School Based Observational Study among Nepali, Indian and Sri Lankan Students

1970 ◽  
Vol 1 (4) ◽  
pp. 135-140 ◽  
Author(s):  
Bedanta Roy ◽  
Indrajit Banerjee ◽  
Brijesh Sathian ◽  
Monami Mondal ◽  
Chhanchu Gopal Saha
Keyword(s):  
Medical Students ◽  
Observational Study ◽  
Blood Group ◽  
Bleeding Time ◽  
Additional Risk Factor ◽  
Sri Lankan ◽  
Clotting Time ◽  
Blood Group A ◽  
Group A ◽  
Indian Students

Background Blood group, Bleeding Time and Clotting time are clinically useful tests, extensively used during blood transfusion, platelet disorders and a variety of forms of treatment in hospitals. The objective of our study was to assess the country wise distribution of blood groups and to compare the country wise bleeding time and clotting time with respect to blood group. Material and Methods This Observational Study has been performed at Manipal College of Medical Sciences, during the period of 1st May 2010 to 31st August–2011. The study was carried out on the undergraduate medical students of Basic sciences and included assessment of Bleeding time, Clotting time and Blood grouping by standard procedures. Results 261 medical students participated in the study. Among the Nepalese students, 30.5% had blood group A, 28.9% B, 5.5% AB and remaining 35.2% O. among the Indian students, 22.8% were blood group A, 45.7% B, 7.6% AB and 23.9% O. In Sri Lankan students, 22% had blood group A, 19.5% B, 4.9% AB, and 53.7% blood group O. Among Nepalese students, BT was higher in blood group A (163.85 seconds) as compared to Indians (154.29Sec) and Sri Lankans (133.33 sec). Nepalese students with AB blood group had higher BT (171.43 sec). Indian students with blood group A had comparatively higher clotting time (328.57 sec) followed by Nepali (276.15 sec) and then Sri Lankan students (270 sec). Girls are 4.432 times more prone for bleeding time greater than 4 minutes and 2.453 times for clotting time value above 6 minutes as compared to males. Conclusion Our study suggests that O blood group is predominant in Nepalese students while Blood group B was the most common blood group in the Indian students. We found higher BT and CT in females, which are more prominent in Indians, so this gender disparity is an additional risk factor for them. Health Ministries of respective countries have to improve the proper health care policies required for prevention and management of blood group diseases, bleeding time and clotting time related disorders like Hypoprothrombinemia and Thrombocytopenia.http://dx.doi.org/10.3126/nje.v1i4.5755 Nepal Journal of Epidemiology 2011;1(4):135-140

Are laryngeal squamous cell carcinoma incidence and patient mortality a function of ABO blood grouping? A retrospective study

2011 ◽  
Vol 126 (2) ◽  
pp. 180-184 ◽  
Author(s):  
S I Adam ◽  
K M Wilson ◽  
S M Overholser ◽  
E Khabbaz ◽  
K Moreno ◽  
...  
Keyword(s):  
Head And Neck ◽  
Blood Group ◽  
Laryngeal Cancer ◽  
Squamous Cell ◽  
Laryngeal Carcinoma ◽  
Survival Rates ◽  
Blood Type ◽  
Advanced Stage Cancer ◽  
Abo Blood Grouping ◽  
Blood Grouping

AbstractObjective:Few studies have examined the association between ABO blood grouping and head and neck cancer. This retrospective review examined the association between blood group and laryngeal cancer incidence and patient mortality.Methods:Of 271 patients treated for squamous cell laryngeal carcinoma (1997–2002), 143 patients with supraglottic, glottic and subglottic tumours were included; 128 patients were excluded. The blood group characteristics of patients and healthy blood donors were compared.Results:There was no significant correlation between blood type and laryngeal carcinoma incidence or mortality. Type A blood was commoner in African Americans with laryngeal cancer than Caucasian patients, but not significantly so. As expected, five-year survival rates were lower in patients with more advanced stage cancer (p < 0.0001).Conclusion:Although our findings show no association between blood group and five-year survival, these results are inconclusive, and warrant further study of the association between blood type and laryngeal (and other) head and neck cancers.

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