New Ray of Hope in Prognosis-Significance of Clinical, Histopathological and Biological Characteristics among Potentially Malignant Disorders and Oral Cancer– Case Series

Author(s):  
G Chandramouli ◽  
CH Reddy ◽  
A Jascinth ◽  
M Anitha ◽  
B Sathvikalakshmi
Healthcare ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 263
Author(s):  
Kamis Gaballah ◽  
Asmaa Faden ◽  
Fatima Jassem Fakih ◽  
Anfal Yousuf Alsaadi ◽  
Nadeen Faiz Noshi ◽  
...  

This study aimed to assess the ability of dental students and recent graduates to detect and recognize mucosal changes that are suggestive of oral cancer and potentially malignant disorders. In this cross-sectional study, a questionnaire was administered to dental students and recent graduates of Ajman University (n = 132). Completed questionnaires were received from 84 (63.6%) females and 48 (36.4%) males which included fifth-year students (n = 80), interns (n = 39), and dental practitioners (n = 13). This questionnaire was designed to assess the respondent’s ability to detect and recognize different types of oral lesions, as well as their knowledge of oral cancer appearance and malignancy potential. The overall accuracy of diagnosis was 46%. The participants correctly identified normal variations, benign tumors, malignant tumors, and premalignant lesions at rates of 60.3%, 31.0%, 55.7%, and 33.4%, respectively. There was no significant difference between the two genders in their ability to recognize and detect correct answers (females, 48.3%; males, 47.2%). According to education level, interns provided the highest percentage of correct answers (52.5%), followed by newly dental practitioners (51.9%) and fifth-year students (44.1%). Conclusion: The respondents of this survey did not exhibit a satisfactory diagnostic capability in recognizing mucosal changes consistent with the clinical presentation of oral cancer. Thus, a need exists for improved and updated educational methods for undergraduate students regarding oral cancer and potentially malignant disorders. Meanwhile, practitioners should look for oral abnormalities to provide better diagnosis and management. Practitioners should also stay up to date on the oral malignancy topic by attending workshops and clinicopathological conferences.


Author(s):  
Paresh Kumar Behera ◽  
Diksha Mohapatra

World Health Organization (WHO) defined the terminology ‘Oral Potentially malignant disorders’ (OPMD) as the presence of risk of malignancy in a lesion or condition either during the time of initial diagnosis or at a future date with the commonly accepted prevalence of 1–5%. All OPMDs may not transform into malignancy, many factors have been explored which effectively assess the risk of malignant transformation in OPMDs including many clinical, pathological and molecular factors. Qualitative & experimental factors of different cells in cytological preparations and/or biopsy specimens are reliable parameters for pathologists. The analysis and assessment of histological units can be enhanced by image analysis assisted by a computer that can be used for statistical comparisons. Fractal geometry is considered to be an ideal method of image analysis in quantitative microscopy & histopathology. Fractal dimension analysis is not only limited to determining cell and tumour types but can also be used for determining cellular behaviours in vitro such as cell migration, apoptosis and cellular differentiation, which can be a useful characterization of oral cancer lines and further help in the treatment planning. Keywords: Oral Cancer, Oral Potentially Malignant Disorders (OPMDs), Conventional morphometry, Fractal Dimension, Photomicrograph


2016 ◽  
Vol 5 (1) ◽  
pp. 52-57
Author(s):  
Neal J Mccormick ◽  
Peter J Thomson ◽  
Marco Carrozzo

Early detection of oral cancer improves survival rates significantly, however, the incidence of oral cancer has continued to rise in the UK – between 2002–2012, it increased by more than 30%.1 There is currently no national screening programme for oral cancer, so undertaking a full examination of the oral mucosa during routine dental appointments is vital. Although strong evidence is still lacking, oral cancer is thought to be preceded by oral potential malignant disorders (OPMDs) or oral precancerous diseases. These mainly present as white/red lesions within the mouth and their clinical appearance can be challenging to diagnose accurately, which can lead to them being misdiagnosed as negligible problems. Dentists must keep up to date with OPMDs detection and ensure they are capable of correctly recognising lesions that carry a potential risk. This paper aims to provide a brief overview on OPMDs, highlighting potentially malignant disorders as they may present to the practitioner, showing their typical clinical appearance, and suggesting differential diagnosis and clinical management in dental practice.


Author(s):  
DANIELA BRITO BASTOS ◽  
VITOR BONETTI VALENTE ◽  
BRUNA AMÉLIA MOREIRA SARAFIM DA SILVA ◽  
SUZY ELAINE NOBRE DE FREITAS ◽  
ANA RITA ALBUQUERQUE ZITO ◽  
...  

2010 ◽  
Vol os17 (2) ◽  
pp. 65-71 ◽  
Author(s):  
Paul R Brocklehurst ◽  
Sarah R Baker ◽  
Paul M Speight

The importance of detecting oral malignant disease is paramount. Recent government strategies have placed an emphasis on the early detection of cancer. This paper presents a brief account of the current debate around the role of oral cancer screening and provides a summary of the results of three practice-based studies that were supported by the British Society for General Dental Surgery and the Faculty of General Dental Practice (UK). Overall, there appears to be a lack of rigour among some general dental practitioners when screening for potentially malignant disorders and their incidence in dental practice is perceived to be low. Barriers remain to the implementation of smoking-cessation schemes and many general dental practitioners feel out of their depth in tackling the abuse of alcohol, despite recognising its importance as a risk factor. Patients continue to present to their general medical practitioner (GMP) when they are concerned about something in their mouth that is not related to their teeth. GMPs’ ability to manage early oral cancer is discussed. A prospective randomised controlled trial (RCT), or a demonstration study, is recommended to investigate the numbers of cases of oral cancer diagnosed in primary dental care and primary medical care and to develop standardised referral criteria for early cases of this disease to reduce under- and over-referral. The RCT could also examine the potential of using auxiliary healthcare workers and examine the impact of such a programme upon secondary care services.


Sign in / Sign up

Export Citation Format

Share Document