scholarly journals Procalcitonin and C-Reactive Protein in Umbilical Cord Blood as Markers for Early Suspicion of Infection in Newborns of Women with Prenatal Urinary Tract Infection

2016 ◽  
Vol 15 (09) ◽  
pp. 37-39
Author(s):  
Rafael Del Castilho Villalba ◽  
Adriana Cersósimo ◽  
Israel Figueiredo ◽  
Adauto Dutra Moraes Barbosa
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Clinical and laboratory features of urinary tract infections in young infants

2018 ◽  
Vol 40 (1) ◽  
pp. 66-72
Author(s):  
Denise Swei Lo ◽  
Larissa Rodrigues ◽  
Vera Hermina Kalika Koch ◽  
Alfredo Elias Gilio
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
C Reactive Protein ◽  
Blood Cell Count ◽  
Group Culture ◽  
Reactive Protein ◽  
Young Infants ◽  
Laboratory Features

ABSTRACT Introduction: Urinary tract infection (UTI) is the most common serious bacterial infection in young infants. Signs and symptoms are often nonspecific. Objectives: To describe clinical, demographic and laboratory features of UTI in infants ≤ 3 months old. Methods: Cross-sectional study of infants ≤ 3 months old with UTI diagnosed in a pediatric emergency department, for the period 2010-2012. UTI was defined as ≥ 50,000 colony-forming units per milliliter of a single uropathogen isolated from bladder catheterization. Paired urinalysis and urine culture from group culture-positive and group culture-negative were used to determine the sensitivity and specificity of pyuria and nitrite tests in detecting UTI. Results: Of 519 urine cultures collected, UTI was diagnosed in 65 cases (prevalence: 12.5%); with male predominance (77%). The most common etiologies were Escherichia coli (56.9%), Klebsiella pneumoniae (18.5%) and Enterococcus faecalis (7.7%). Frequent clinical manifestations were fever (77.8%), irritability (41.4%) and vomiting (25.4%). The median temperature was 38.7°C. The sensitivity of the nitrite test was 30.8% (95%CI:19.9-43.4%), specificity of 100% (95%CI:99.2-100%). Pyuria ≥ 10,000/mL had a sensitivity of 87.7% (95%CI:77.2-94.5%), specificity of 74.9% (95%CI:70.6 -78.8%). The median peripheral white blood cell count was 13,150/mm3; C-reactive protein levels were normal in 30.5% of cases. Conclusions: The male: female ratio for urinary tract infection was 3.3:1. Non-Escherichia coli etiologies should be considered in empirical treatment. Fever was the main symptom. Positive nitrite is highly suggestive of UTI but has low sensitivity; whereas pyuria ≥ 10,000/mL revealed good sensitivity, but low specificity. Peripheral white blood cell count and C-reactive protein concentration have limited usefulness to suggest UTI.

Do Serum C-reactive Protein and Interleukin-6 Predict Kidney Scarring After Urinary Tract Infection?

2013 ◽  
Vol 80 (12) ◽  
pp. 1002-1006 ◽  
Author(s):  
Luis Miguel Rodríguez ◽  
Belén Robles ◽  
José Manuel Marugán ◽  
Ángeles Suárez ◽  
José María García Ruiz de Morales
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Interleukin 6 ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Kidney Scarring

scholarly journals C - reactive protein and urinary tract infection due to Gram-negative bacteria in a pediatric population at a tertiary hospital, Mwanza, Tanzania

1970 ◽  
Vol 19 (4) ◽  
pp. 3217-3224
Author(s):  
Martha F Mushi ◽  
Vaileth G Alex ◽  
Mwanaisha Seugendo ◽  
Vitus Silago ◽  
Stephen E Mshana
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Enteric Bacteria ◽  
Gram Negative Bacteria ◽  
C Reactive Protein ◽  
Gram Negative ◽  
Reactive Protein ◽  
Significant Bacteriuria ◽  
Tract Infections

Introduction: Gram-negative bacteria are the major cause of urinary tract infections (UTI) in children. There is limited data on UTI systemic response as measured using C-reactive protein (CRP). Here, we report the association of CRP and UTI among children attending the Bugando Medical Centre, Mwanza, Tanzania.Methods: A cross-sectional study was conducted between May and July 2017. Urine and blood were collected and processed within an hour of collection. Data were analyzed using STATA version 13.Results: Of 250 enrolled children, 76(30.4%) had significant bacteriuria with 56(22.4%, 95%CI; 11.5-33.3) having gram-negative bacteria infection. There was dual growth of gram-negative bacteria in 3 patients. Escherichia coli (32.2%, 19/59) was the most frequently pathogen detected. A total of 88/250(35.2%) children had positive CRP on qualitative assay. By multinomial logistic regression, positive CRP (RRR=4.02, 95%CI: 2.1-7.7, P<0.001) and age ≤ 2years (RRR=2.4, 95%CI: 1.23-4.73, P<0.01) significantly predicted the presence of significant bacteriuria due to gram-negative enteric bacteria. Conclusion: C-reactive protein was significantly positive among children with UTI due to gram-negative bacteria and those with fever. In children with age ≤ 2 years, positive CRP indicates UTI due to gram-negative enteric bacteria.Keywords: C - reactive protein, urinary tract infection, Gram-negative bacteria, Mwanza, Tanzania.

scholarly journals Serial concentrations of C-reactive protein as an indicator of urinary tract infection in patients with spinal injury.

1986 ◽  
Vol 39 (8) ◽  
pp. 851-855 ◽  
Author(s):  
A Galloway ◽  
H T Green ◽  
J J Windsor ◽  
K K Menon ◽  
B P Gardner ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Spinal Injury ◽  
C Reactive Protein ◽  
Reactive Protein
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