Reviewing the Analeptic Activity of Calcium Citrate Malate

Calcium Citrate Malate’s (CCM) health benefits were patented over three decades ago. It is involved in calcium retention, in children and adolescents. In adulthood, it is seen to promote the maintenance of bone health. In conjunction with vitamin D, CCM also decreases the risk of bone fracture in aged people and ensures that postmenopausal women’s health is made better. CCM, unlike other supplements, does not need to be taken along with a meal and is seen to deliver benefits to individuals of any age group. CCM is usually used when the person has achlorhydria where the gastric acid secretion is reduced and there is an absence of an acidic environment (required by calcium carbonate). Calcium citrate Malate possesses outstanding bioavailability properties and is a useful extension to the calcium available presently, either for direct supplementation or for food fortification.

Preparation of Calcium Citrate Malate Using Citric Acid and Malic Acid with Calcium Hydroxide Synthesized from Duck Eggshell

This research work presents an optimum setting at which the production of calcium citrate malate would have the highest yield. The factors that were varied are temperature and the concentrations of citric acid and malic acid. Duck eggshells were used as the source of calcium. The temperature settings were at room temperature (25°C) and at 80°C, the concentrations of citric acid at 1.5 M and 1.7 M and that of malic acid at 2.2 M and at 2.5 M. Using 23 factorial design of experiment (8 settings), the main effects and the interaction effects were plotted to derive an empirical model to predict the yield of calcium citrate malate. Furthermore, a comparison of x-ray diffraction graphs was conducted to evaluate the final product.