Morphometric Liver Study in Adults

Background: The aim is to study the dimensions of the adult liver in Senegal in order to contribute to the data of the manufacture of a peri-hepatic prosthesis wrapping in the therapeutic means of post-traumatic hemorrhagic lesions of the liver. Materials and methods: This study involved 50 livers of anatomical subjects with an average age of 38 years. We have noted some biometric parameters. On the livers collected, we measured the weight and some dimensions. Results: The intermediate morphotype predomined with 48% of cases. The dorso-petal position of the liver was observed in 84% of the subjects. There was no correlation between the morphotype of the subjects and the orientation of the visceral face of the liver. The average liver weight was 1410 g. The average transverse diameter was 25.77cm while the antero-posterior diameter of the right lobe was 16 cm. The sagittal circumference of the liver in the sickle cell ligament was significantly lower than those measured at the right and left lobes. The sagittal circumferences of the liver in the Breviligneous subject were lower than those of the intermediate and long morphotype subjects. Conclusion: The choke zone between the two lobes of the liver in the sickle cell ligament is a mooring point for the peri-hepatic wrapping prosthesis. However, this can only be segmental for each right and left lobe. The morphotype of the subject, however, affects the weight, thickness and sagittal circumferences of the liver, which are essential for the dimensions of a peri-hepatic prosthesis. KEY WORDS: Liver morphometric, peri-hepatic prosthesis.

Структурні та морфометричні зміни печінки при експериментальній термічній травмі

СТРУКТУРНІ ТА МОРФОМЕТРИЧНІ ЗМІНИ ПЕЧІНКИ ПРИ ЕКСПЕРИМЕНТАЛЬНІЙ ТЕРМІЧНІЙ ТРАВМІ - В експерименті на морських свинках проведено мікроскопічні та морфометричні дослідження печінки в динаміці. Після тяжкої термічної травми встановлено, що у стадії токсемії були характерні зміни судин та паренхіми органа, що носять пристосувально-компенсаторний характер. У пізні терміни після опіку (стадії пізньої токсемії та септикотоксеміі) виявлено значну деструкцію вен, судин тріад та гемокапілярів, вміст темних клітин у часточках зростає, в темних і світлих гепатоцитах значно змінюються ядерно-цитоплазматичні співвідношення, що свідчить про пригнічення процесів регенерації.<br />СТРУКТУРНЫЕ И МОРФОМЕТРИЧЕСКИЕ ИЗМЕНЕНИЯ ПЕЧЕНИ ПРИ ЭКСПЕРИМЕНТАЛЬНОЙ ТЕРМИЧЕСКОЙ ТРАВМЕ - В эксперименте на морских свинках проведены микроскопические и морфометрические исследования печени в динамике. После тяжелой термической травмы установили, что в стадии токсемии были характерные изменения сосудов и паренхимы органа и носят приспособительно-компенсаторный характер. В поздние сроки после ожога (стадии поздней токсемии и септикотоксемии) обнаружена значительная деструкция вен, сосудов триад и гемокапилляров, количество темных клеток в дольках растет, в темных и светлых гепатоцитах значительно меняются ядерно-цитоплазматические соотношения, что свидетельствует об угнетении процессов регенерации.<br />STRUCTURAL AND MORPHOMETRIC CHANGES OF LIVER IN EXPERIMENTAL THERMAL TRAUMA - Іп experiment on gvinea pigs with thermal ingury of skin was investigated the histological and morphometrical changes of liver. The obtained results showed in toxemia stage changes in blood vessels and parenchyma of the body that are adaptative-compensatory character. In later stages after the burn (stage late toxemia and septicotoxemia) found significant degradation veins, vascular triads and hemocahilares, namber of dark hepatocytes increases. In dark and light hepatocytes canges nuclear-cytoplasmic ratio, which means inhibition of regeneration.<br />Ключові слова: печінка, гістологічні та морфометричні зміни, термічна травма.<br />Ключевые слова: печень, гистологические и морфометрические изменения, термическая травма.<br />Key words: liver, histological and morphometrical changes, thermal trauma.

Etiology, Presentation and Management of Liver Abscesses at the Children’s Hospital Lahore

Background: Liver abscess is a common problem among children. The purpose of this study is to describe the etiology, different management strategies and outcome of children with liver abscess in Children’s Hospital Lahore. Patients and Methods: This study included 38 children with liver abscess seen during two-year period, from September 2004 to September 2006 at the Children’s Hospital and Institute of Child Health, Lahore. Diagnosis was made on history, examination and investigations. Ultrasound and CT scan were the main diagnostic tools. Results: Out of 38 patients, 33 children underwent aspiration and remaining 5 were managed conservatively. Eight aspirates yielded positive culture for various organisms. Three patients were positive for E.Coli, 2 for Staph Aureus, and 1 each case of Klebsiella and Pseudomonas. One patient had multiple micro-abscesses and was also positive for typhidot IgM. Another patient was positive for acid fast mycobacterium tuberculosis. All patients recovered from their abscesses. There was no mortality reported. Conclusions: In our pediatric population, liver abscess are mostly caused by pyogenic organisms. Amebic etiology was not proven in any case. Majority of liver abscesses can be satisfactorily treated by aspiration and /or percutaneous image guided drainage with satisfactory outcome. Key Words: Liver abscess, children.

A LIVER BIOPSY INSTRUMENT FOR LARGE ANIMALS

A new liver biopsy instrument for large animals was manufactured and used to obtain samples in the range of 150–350 mg fresh weight from dairy cattle. Difficulties with the aspiration procedure caused by inadequate control of suction and excessively deep penetration of the liver were eliminated with the new instrument. Key words: Liver biopsy instrument, large animals

Parasitic Liver Abscess Caused By Ascaris Lumbricoides - A Case Report

This is a case report of a middle aged man who presented with weight loss and epigastric pain. The initial diagnosis was space occupying lesion in liver. The mass was later demonstrated by trans-abdominal percutaneous needle biopsy to be an abscess caused by Ascaris lumbricoides. Fertilized Eggs and Larvae of Ascaris lumbricoides was found. Key Words: Liver Abscess; Ascaris Lumbricoides DOI: 10.3329/akmmcj.v1i2.7462 Anwer Khan Modern Medical College Journal 2010; 1(2): 25-26

Pathological investigation of liver of the slaughtered buffaloes in Barisal district

Livers (n = 80) of slaughtered adult buffaloes were examined for pathological changes during the period from July 2006 to March 2007 in two slaughterhouses of Barisal district. Livers exhibiting gross alterations were cleaned with normal neutral saline and the changes were recorded. The lesions containing tissue samples were collected in 10% buffered formalin for fixation. Grossly, Gigantocotyle explanatum infection (amphistomiasis) was found in 31.25% and Fasciola gigantica infection was in 22.5% cases. Hydatidosis (2.5%), abscesses (3.75%), and haemorrhages (2.5%) were found in the liver. Histopathologically, cirrhosis was found in 31.25% cases. Nodular hepatitis 7.5%, granulomatous hepatitis 5% and parasitic cholecystitis 15% were also recorded during the investigation. Survey showed that the severity of infection with G. explanatum 31.25% and F. gigantica 22.5% and cirrhosis 31.25% were of highest percentage. Â Key words: Liver, amphistomiasis, hydatidosis, granulomatous, cholecystitis, cirrhosis, Fasciola gigantica DOI = 10.3329/bjvm.v5i1.1321 Bangl. J. Vet. Med. (2007). 5 (1 & 2): 81-85