In this paper, we consider a certain integral operator with a weight, loaded with operator term. It acts in the space of continuous functions. The conditions under which this operator is limited are determined, the form of its semigroup is es-tablished. The Cauchy problem for an integro-differential equation is considered as an application. Such equations arise in the theory of elasticity and models of biological processes: Proctor's problem on the equilibrium of an elastic beam, Volterra's problem on torsional vibrations, Prandtl's problem for calculating an airplane wing, in analysis of economic models, etc.