charged particle
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2022 ◽  
Vol 8 (2) ◽  
Author(s):  
Elias Roussos ◽  
Christina Cohen ◽  
Peter Kollmann ◽  
Marco Pinto ◽  
Norbert Krupp ◽  
...  

A local charged particle source in Jupiter’s inner radiation belts generates oxygen ions of cosmic ray energies.


2022 ◽  
Vol 11 ◽  
Author(s):  
Dandan Wang ◽  
Ruifeng Liu ◽  
Qiuning Zhang ◽  
Hongtao Luo ◽  
Junru Chen ◽  
...  

PurposeGiven the higher precision accompanied by optimized sparing of normal tissue, charged particle therapy was thought of as a promising treatment for pancreatic cancer. However, systematic preclinical studies were scarce. We aimed to investigate the radiobiological effects of charged particle irradiation on pancreatic cancer cell lines.MethodsA systematic literature search was performed in EMBASE (OVID), Medline (OVID), and Web of Science databases. Included studies were in vitro English publications that reported the radiobiological effects of charged particle irradiation on pancreatic cancer cells.ResultsThirteen carbon ion irradiation and seven proton irradiation in vitro studies were included finally. Relative biological effectiveness (RBE) values of carbon ion irradiation and proton irradiation in different human pancreatic cancer cell lines ranged from 1.29 to 4.5, and 0.6 to 2.1, respectively. The mean of the surviving fraction of 2 Gy (SF2) of carbon ion, proton, and photon irradiation was 0.18 ± 0.11, 0.48 ± 0.11, and 0.57 ± 0.13, respectively. Carbon ion irradiation induced more G2/M arrest and a longer-lasting expression of γH2AX than photon irradiation. Combination therapies enhanced the therapeutic effects of pancreatic cell lines with a mean standard enhancement ratio (SER) of 1.66 ± 0.63 for carbon ion irradiation, 1.55 ± 0.27 for proton irradiation, and 1.52 ± 0.30 for photon irradiation. Carbon ion irradiation was more effective in suppressing the migration and invasion than photon irradiation, except for the PANC-1 cells.ConclusionsCurrent in vitro evidence demonstrates that, compared with photon irradiation, carbon ion irradiation offers superior radiobiological effects in the treatment of pancreatic cancer. Mechanistically, high-LET irradiation may induce complex DNA damage and ultimately promote genomic instability and cell death. Both carbon ion irradiation and proton irradiation confer similar sensitization effects in comparison with photon irradiation when combined with chemotherapy or targeted therapy.


Author(s):  
Ingo Fischer ◽  
Stephen T Pratt

Photoelectron spectroscopy has long been a powerful method in the toolbox of experimental physical chemistry and molecular physics. Recent improvements in coincidence methods, charged-particle imaging, and electron energy resolution have...


Author(s):  
E. V. Vakulina ◽  
V. V. Andreev ◽  
N. V. Maksimenko

In this paper, we obtained a solution for the equation of motion of a charged spinless particle in the field of a plane electromagnetic wave. Relativistic expressions for the cross section of Compton scattering by a charged particle of spin 0 interacting with the field of a plane electromagnetic wave are calculated. Numerical simulation of the total probability of radiation as the function of the electromagnetic wave amplitude is carried out. The radiation probability is found to be consistent with the total cross section for Compton scattering by a charged particle of spin 0.


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