salt hydrate
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2022 ◽  
Vol 154 ◽  
pp. 111846
Author(s):  
Wei Li ◽  
Jiří Jaromír Klemeš ◽  
Qiuwang Wang ◽  
Min Zeng
Keyword(s):  

Cellulose ◽  
2022 ◽  
Author(s):  
Liang Zhou ◽  
Qiyu Liu ◽  
Qiaozhi Ma ◽  
Mingzhao Guan ◽  
Xinping Ouyang ◽  
...  

Author(s):  
Yuzhan Li ◽  
Navin Kumar ◽  
Jason Hirschey ◽  
Damilola O. Akamo ◽  
Kai Li ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6927
Author(s):  
Xinling Zeng ◽  
Qing Zhou ◽  
Liyan Wang ◽  
Xiaoxian Zhu ◽  
Kuiyan Cui ◽  
...  

It is important to detect thrombin due to its physiological and pathological roles, where rapid and simple analytical approaches are needed. In this study, an aptasensor based on fluorescence attenuation kinetics for the detection of thrombin is presented, which incorporates the features of stilbene and aptamer. We designed and synthesized an aptasensor by one-step coupling of stilbene compound and aptamer, which employed the adaptive binding of the aptamer with thrombin to cause a change in stilbene fluorescence attenuation kinetics. The sensor realized detection of thrombin by monitoring the variation in apparent fluorescence attenuation rate constant (kapp), which could be further used for probing of enzyme–aptamer binding. In comprehensive studies, the developed aptasensor presented satisfactory performance on repeatability, specificity, and regeneration capacity, which realized rapid sensing (10 s) with a limit of detection (LOD) of 0.205 μM. The strategy was successful across seven variants of thrombin aptasensors, with tunable kapp depending on the SITS (4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate) grafting site. Analyte detection mode was demonstrated in diluted serum, requiring no separation or washing steps. The new sensing mode for thrombin detection paves a way for high-throughput kinetic-based sensors for exploiting aptamers targeted at clinically relevant proteins.


2021 ◽  
pp. 103554
Author(s):  
Joey Aarts ◽  
Stan de Jong ◽  
Martina Cotti ◽  
Pim Donkers ◽  
Hartmut Fischer ◽  
...  

Author(s):  
Anna A. Gaydamaka ◽  
Sergey G. Arkhipov ◽  
Elena V. Boldyreva

A new guanine salt hydrate, K+·C5H4N5O−·H2O, was obtained and characterized by single-crystal X-ray diffraction in the temperature range 100 K–300 K and compared with that of the previously documented sodium salt hydrate (2Na+·C5H3N5O2−·7H2O) [Gur & Shimon (2015). Acta Cryst. E71, 281–283; Gaydamaka et al. (2019). CrystEngComm, 21, 4484–4492]. Both sodium and potassium salt hydrates have channels. However, the structure of the channels, the cation coordination, the protonation (and, respectively, the charge) of the guanine anions, as well as the role of water molecules in the crystal structure are different for the two salt hydrates. In the crystal structures of the potassium salt, the guanine anions are linked via hydrogen bonds into quartets that form open cylindrical channels in a honeycomb framework. Water molecules `line the walls' of the channels, whereas the potassium cations fill the intra-channel space. This contrasts with the structure of the sodium salt hydrate in which guanine anions form channels with water molecules filling in the channel space together with sodium cations coordinating them. The 1D anionic assembly generated through numerous hydrogen bonds and cation interactions with guanine anions and water molecules is energetically the most distinctive part of the structure of the potassium salt hydrate. In the case of the guanine sodium salt, the structure contains purely inorganic polymeric fragments – sodium cations coordinated to a water molecule forming a 1D polymeric structure and guanine anions interconnecting these polymers via hydrogen bonds with water molecules. The structural differences account for the difference in the anisotropy of strain on temperature variation for the two salt hydrates: whereas in both structures the values of the bulk thermal expansion coefficients are similar in the two structures and the major expansion is observed along the channel axes, the degree of anisotropy for the K salt is more than four times higher than that for the Na salt.


Author(s):  
Anna Martinelli ◽  
José M. Otero-Mato ◽  
Mounesha N. Garaga ◽  
Khalid Elamin ◽  
Seikh Mohammad Habibur Rahman ◽  
...  

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