Abstract
A different approach to continuous-flow analysis is described, in which the initial reagent concentration is adjusted to fit a prefixed manifold while still providing optimum concentrations of the reactants in the mixing coils. A single-channel AutoAnalyzer so designed can perform multiple tests without the need to change manifolds. The system was assembled from a Technicon Sampler II and Pump II, a Gilford 300 N spectrophotometer, and a Varian recorder. Results for calcium, uric acid, glucose, phosphorus, chloride, urea nitrogen, and carbon dioxide, analyzed on this instrument at a speed of 60 samples/ h, compare favorably with those obtained with the AutoAnalyzer 12/60 and 6/60. The instrument is not restricted to certain methodologies and, in addition, can be used manually or for kinetic reactions