A case of male infanticide in captive sika deer (Cervus nippon)

Male infanticide has been reported in wide range of mammalian taxa however it remains very rare in even-toed ungulates where it was documented in two species only. Among six hypotheses explaining this phenomenon, the sexual selection hypothesis is supported by the largest evidence in mammals. Here, we report the first case of male infanticide in sika deer (Cervus nippon) which occurred at Ostrava Zoo. At the end of rutting season, new male had been joined with two pregnant females that successfully gave birth and reared offspring in his presence then. However, in the next season, the same male attacked and killed his own newborn female offspring. Since this male was separated from the herd for most of the time in the rut, we argue that he could be confused about paternity. Therefore, this case of infanticide might be driven by the same mechanism as that which is in line with the sexual selection hypothesis. In addition, based on our evidence we cannot reject the social pathology hypothesis as an alternative explanation.

Aggression towards neonates and possible infanticide in the boto, or Amazon river dolphin (Inia geoffrensis)

Recent observed attacks by male Amazon river dolphins on conspecific calves, together with post-mortem examinations, indicate that infanticide occurs in this species but that not all attacked calves are killed. If mortality occurs, it might therefore be an inadvertent consequence of the behaviour rather than the motive for it. Our observations suggest that males who commit infanticide are unlikely to gain direct fitness benefits. Evidence does not fit the sexual selection hypothesis. Aggression towards calves usually ‘drew a crowd’ and may represent socio-sexual display or simply be a form of social pathology, as found in other infanticidal mammals.

Who benefits from attending elite universities? Family background and graduates' career trajectories

The literature on social stratification has paid considerable attention to whether and to what extent attending prestigious universities is advantageous for graduates’ labor market returns. This paper contributes to the literature by applying a more dynamic perspective in asking whether graduates from prestigious and less prestigious universities differ in their career progression across fourteen years since labor market entry. It further investigates whether graduating from prestigious universities pays off more or less for graduates from different educational backgrounds. The positive selection hypothesis suggests that students most likely to attend prestigious universities will benefit the most. The negative selection hypothesis suggests the opposite. Using multilevel growth curve modeling and the 1970 British Cohort Study (N = 939), the findings show no discernible differences in occupational prestige between graduates from diverse universities. If at all, there is a small Russell Group premium restricted to the early working career. This early Russell Group premium is only found among first-generation graduates providing evidence for the negative selection hypothesis.

From Posttranslational Modifications to Disease Phenotype: A Substrate Selection Hypothesis in Neurodegenerative Diseases

A number of neurodegenerative diseases including prion diseases, tauopathies and synucleinopathies exhibit multiple clinical phenotypes. A diversity of clinical phenotypes has been attributed to the ability of amyloidogenic proteins associated with a particular disease to acquire multiple, conformationally distinct, self-replicating states referred to as strains. Structural diversity of strains formed by tau, α-synuclein or prion proteins has been well documented. However, the question how different strains formed by the same protein elicit different clinical phenotypes remains poorly understood. The current article reviews emerging evidence suggesting that posttranslational modifications are important players in defining strain-specific structures and disease phenotypes. This article put forward a new hypothesis referred to as substrate selection hypothesis, according to which individual strains selectively recruit protein isoforms with a subset of posttranslational modifications that fit into strain-specific structures. Moreover, it is proposed that as a result of selective recruitment, strain-specific patterns of posttranslational modifications are formed, giving rise to unique disease phenotypes. Future studies should define whether cell-, region- and age-specific differences in metabolism of posttranslational modifications play a causative role in dictating strain identity and structural diversity of strains of sporadic origin.