Radiation protection study for a reloading operation of cobalt 60 sources in the Moroccan ionisation station using the GEANT4 Monte-Carlo simulation code

The operation of reloading the irradiators is considered among the tasks requiring high radiation protection monitoring, to protect the intervening manipulators, the public and the environment. Morocco is among the countries that have a cobalt irradiator, installed at the National Institute of Agricultural Research (NIAR) of Tangier, to carry out research in the field of agronomy. In the beginning, the irradiator used low doses of activity for the study of products only, for treatment of high doses. The NIAR carried out a reload to increase the activity. To perform this, a temporary pool was installed inside the irradiation room to handle the sources safely. A radiation protection study is necessary to ensure the safe operation. This operation requires a height level of exposure. To ovoid the exposer risk, it is proposed to use the Monte Carlo method thanks to its reliability in the dosimetric calculation. This article presents a radiation protection study of the Moroccan irradiator reloading operation using the GEANT4 Monte-Carlo Simulation Code.

Characterization of the Canberra BE5030 Broad Energy High Purity Germanium Detector by means of the GEANT4 Monte Carlo simulation package

The accurate determination of the efficiency of HPGe detectors is a challenging procedure due to possible self-attenuation phenomenaand/or coincidence summing effects. Both of these phenomena become important when close detection geometries and extended samples are considered. To deal with these features the simulation of HPGe detectors is used so as to calculate the corresponding correction factors, especially for those cases where low energy γ-ray are considered. Through the present work the Canberra BE5030 Broad Energy HPGe detector of the Enviromental Radioactivity Monitoring Department of Greek Atomic Energy Comission was simulated through the GEANT4 toolkit. Experimental efficiency and counting rate data were compared with the simulation results for different geometries of the detector so as to idetify the one for which the experimental data are better reproduced.

Single-cell radioluminescence microscopy with two-fold higher sensitivity using dual scintillator configuration

Radioluminescence microscopy (RLM) is an imaging technique that allows quantitative analysis of clinical radiolabeled drugs and probes in single cells. However, the modality suffers from slow data acquisition (10 – 15 minutes), thus critically affecting experiments with short-lived radioactive drugs. To overcome this issue, we suggest an approach that significantly accelerates data collection. Instead of using a single scintillator to image the decay of radioactive molecules, we sandwiched the radiolabeled cells between two scintillators. As proof of concept, we imaged cells labeled with [18F]FDG, a radioactive glucose popularly used in oncology to image tumors. Results show that the double scintillator configuration increases the microscope sensitivity by two-fold, thus reducing the image acquisition time by half to achieve the same result as the single scintillator approach. The experimental results were also compared with Geant4 Monte Carlo simulation to confirm the two-fold increase in sensitivity with only minor degradation in spatial resolution. Overall, these findings suggest that the double scintillator configuration can be used to perform time-sensitive studies such as cell pharmacokinetics or cell uptake of short-lived radiotracers.