Calcium is the most essential element to provide energy to the body system and PTH secretion is responsible for the calcium regulations. PTH imbalance can cause serious medical conditions. Heat is one of the factors that is able to cause disturbance in the PTH secretion. As ultrasound has the potential to produce heat, its imprudent use during pregnancy may cause disturbance in the formation of the parathyroid gland. This study was done using young-aged oryctolagus cuniculus to evaluate PTH secretion and its correlation with the biochemical reaction and bone volume. New Zealand White rabbits were time-mated and exposed to 30, 60 and 90 minutes of prenatal ultrasound at 1st, 2nd and 3rd stage of gestation accordingly. The control group was left for full term delivery without receive ultrasound exposure. In 1 month-aged subject, the lowest PTH level which significantly different from the control was noted after exposed prenatally in the 1st stage for 90min (3.56±0.75). Meanwhile, in the 5 months-aged subject, the lowest PTH level was noted in the 3rd stage group after 90min of exposure (2.98±0.62). The reduction in PTH was found to affect the biochemical reactions, but not the bone volume.
Vitamin D deficiency osteomalacia triggered by long-term social withdrawal and unbalanced diet in a Japanese middle-aged subject
