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2022 ◽  
Vol 204 ◽  
pp. 112021
Author(s):  
Arce Domingo-Relloso ◽  
Anne Bozack ◽  
Samara Kiihl ◽  
Zulema Rodriguez-Hernandez ◽  
Pilar Rentero-Garrido ◽  
...  

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Mark Terrelonge ◽  
Sara C. LaHue ◽  
Christopher Tang ◽  
Irina Movsesyan ◽  
Clive R. Pullinger ◽  
...  

AbstractDespite the association between cognitive impairment and delirium, little is known about whether genetic differences that confer cognitive resilience also confer resistance to delirium. To investigate whether older adults without postoperative delirium, compared with those with postoperative delirium, are more likely to have specific single nucleotide polymorphisms (SNPs) in the FKBP5, KIBRA, KLOTHO, MTNR1B, and SIRT1 genes known to be associated with cognition or delirium. This prospective nested matched exploratory case–control study included 94 older adults who underwent orthopedic surgery and screened for postoperative delirium. Forty-seven subjects had incident delirium, and 47 age-matched controls were not delirious. The primary study outcome was genotype frequency for the five SNPs. Compared with participants with delirium, those without delirium had higher adjusted odds of KIBRA SNP rs17070145 CT/TT [vs. CC; adjusted odds ratio (aOR) 2.80, 95% confidence interval (CI) 1.03, 7.54; p = 0.04] and MTNR1B SNP rs10830963 CG/GG (vs. CC; aOR 4.14, 95% CI 1.36, 12.59; p = 0.01). FKBP5 SNP rs1360780 CT/TT (vs. CC) demonstrated borderline increased adjusted odds of not developing delirium (aOR 2.51, 95% CI 1.00, 7.34; p = 0.05). Our results highlight the relevance of KIBRA, MTNR1B, and FKBP5 in understanding the complex relationship between delirium, cognition, and sleep, which warrant further study in larger, more diverse populations.


2022 ◽  
pp. 44-62
Author(s):  
Benjamin Jules ◽  
Geny Moreno ◽  
Charlotte Fontenot

In recent years, our society has experienced a major renaissance regarding cultural and personal beliefs, which has affected the overall environment and traditions within our current school settings, thus the need for integrating multicultural theoretical practices to ensure success for diverse populations within Pre-K-12 and postsecondary education. According to Guo and Jamal, there is a need for learning environments to embrace diversity and engage in the personification of respect for the views, beliefs, and values of students. This body of work is focused on the identification of barriers surrounding academic achievement for diverse learners in the Pre-K-12 and postsecondary settings and provides useful tools and strategies that educators may use to further support diverse learners.


2022 ◽  
Vol 39 (1) ◽  
pp. 16-21
Author(s):  
Ruth-Alma N. Turkson-Ocran ◽  
Manka Nkimbeng ◽  
Daffcar Erol ◽  
DaSol Amy Hwang ◽  
Akasi A. Aryitey ◽  
...  

2022 ◽  
Vol 38 (1) ◽  
Author(s):  
Angelo Brandelli Costa ◽  
Letícia de Oliveira Rosa ◽  
Anna Martha Vaitses Fontanari

Abstract: Correctly recognizing gender identity in population-based surveys is essential to develop effective public health strategies to improve the living conditions of transgender and gender-diverse populations, as well as to adequately collect data on cisgender individuals. This study aims to present the two-step measure as the best strategy for assessing gender identity in Brazilian surveys, thus we performed two separate analyses. Firstly, we conducted a systematic review concerning HIV-related care among Brazilian transgender and gender-diverse populations to assess the strategy used to identify participants’ gender identity. Secondly, we re-analyzed data from a recent survey that included Brazilian transgender populations, comparing characteristics and health outcomes from the sample identified by single-item and by the two-step measure. Concerning the systematic review, from 6,585 references, Brazilian research teams published seven articles, and only one study used the two-step measure. Regarding this survey, the two-step measure recognized 567 cisgender and 773 transgender and gender diverse participants among the 1,340 participants who answered the questionnaire, whereas the single-item measure was able to recognize only 540 transgender and gender diverse people. Furthermore, 31 transgender women self-identified as “transgender men” on the single-item measure. Therefore, although scarcely used in Brazil, the two-step measure is a more accurate strategy to recognize gender identity.


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