The synthesis of 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and its interaction with aldehydes

Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reactionwith aldehydes.Results and discussion. 4-Amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol was synthesized, and a number of 4-(ethyl, aryl)idenamino derivatives were obtained on its basis.Experimental part. Using a series of four successive reactions based on quinoline-2-carboxylic acid, 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol was synthesized; its interaction with aldehydes allowed to obtain a number of 4-(ethyl, aryl)idenamino derivatives. The structure of all compounds synthesized was confrmed by IR and 1H NMR spectroscopy, as well as by elemental analysis, and their purity by thin layer chromatography.Conclusions. 4-Amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol has been synthesized. It has been found that its interaction with aldehydes leads to the formation of new 4-((ethyl, aryl)idenamino)-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiols.Key words: 5-(quinolin-2-yl)-1,2,4-triazole-3-thiol; 4-arylidenamino derivatives; quinaldic acid; biologicalactivity

Кристаллическая структура, люминесценция и триболюминесценция комплекса [Eu-=SUB=-2-=/SUB=-(Quin)-=SUB=-4-=/SUB=-2H-=SUB=-2-=/SUB=-O2Dipy]-=SUB=-2-=/SUB=-(NO-=SUB=-3-=/SUB=-)-=SUB=-2-=/SUB=-H-=SUB=-2-=/SUB=-O

An atomic structure of crystals of the complex [Eu_2(Quin)_42Н_2O2Dipy]_2 · 2(NO_3) · Н_2O, (Quin, anion of quinaldic acid; Dipy, 2,2'-dipyridyl), which exhibited intense luminescence and triboluminescence, has been investigated via the X-ray diffraction analysis. The structure of crystals of the compound appeared to be of an islelike type and were represented by two separate crystallographically independent complex dimers, outer-sphere [NO_3]^−1-groups, and water molecules. Structural aspects of the formation of the luminescent and triboluminescent properties of the compound have been discussed. The role of cleavage planes at crystal destruction has been established.