Clinicopathological Study of Supraglottic Carcinoma of Larynx

Introduction: Incidence of supraglottic carcinoma is more common which may be related to poor nutrition with personal habit like smoking and chewing habit of betel leaves with various ingredient. Objectives: To find out the incidence, age and sex distribution, occupation and clinical presentation of supraglottic carcinoma of larynx. Materials and Methods: In this prospective study, 30 patients of supraglottic carcinoma are collected from department of ENT and Head-Neck surgery, Combined Military Hospital, Dhaka from July 2012 to July 2013. Results: Patients belongs to different age groups, ranging from 40 to 80 years and maximum patients are in 50 to 60 years of age. The male to female ratio is 5:1. In this series, majority of patients are smoker (66.66%). Most of them are from low socio-economic group. The incidence of lymph node involvement is 40% (12 cases). Maximum number of patients presents with exophytic lesion (60%). Ulcerative lesions are 26.66% and infiltrative lesions are 13.33%. Maximum numbers of patients have T2 lesions (80%). T1 lesions are 20%. In this study all cases are histopathologically confirmed to be squamous cell carcinoma (100%). In this study, all cases are M0 state. Conclusion: Supraglottic carcinoma occurs between 40-80 years of age, more common in 5th and 6th decades. Chewing betel nut and tobacco should be avoided to reduce the risk of supraglottic carcinoma and early presentation & diagnosis will improve the prognosis of patients. JAFMC Bangladesh. Vol 15, No 2 (December) 2019: 224-226

Clinical study of carcinoma of larynx: a retrospective analysis

<p><strong>Background:</strong> Carcinoma of larynx is the third most common cancer in head and neck, sixth most common cancer among men in India. This study aims to identify the patterns of clinical presentation, epidemiological features and management of laryngeal carcinoma in a tertiary care centre of Indian armed forces.</p><p><strong>Methods</strong>: This is a retrospective analysis of patients admitted in a Command hospital from January 2007 to December 2009.</p><p><strong>Results</strong>: A total of 28 patients were treated in 3 year duration. All the patients were males. The majority of patients belonged to 7^th decade of life with youngest 49 years old and the oldest 80 years. Supraglottic carcinoma (71%) was the most common laryngeal carcinoma followed by glottic carcinoma(29%).Hoarseness of voice (82%) was the most common presenting complaint followed by dysphagia (42%) and dysponea (21%). 32% of patients reported after initial emergency tracheostomy. 12 (42%) patients were treated with curative surgery, 4 (14%) were treated with curative radiotherapy. Rest of patients required palliative therapy.</p><p><strong>Conclusions:</strong> Laryngeal carcinoma is found predominantly in males at seventh decade of life and advanced stage. Treatment with curative intent may be possible in around 70% of patients<strong>.</strong></p>

A Case of Verrucous Carcinoma of Larynx

A 50 years old male patient was admitted with complaints of change in voice for 2 years, dry cough 2 month and difficulty in breathing for 1 month. On examination with fiberoptic laryngoscope, an exophytic lesion covered with whitish plaque involving right vocal cord extending from anterior commissure to right arytenoid region, extending upto the right vestibular area and hanging in the subglottic area was seen. Patient was treated with Microlaryngeal Laser excision and the Histopathology report was suggestive of Verrucous Carcinoma of Larynx. Bangladesh J Otorhinolaryngol; October 2017; 23(2): 208-211

Frequency of Lympnode Metastasis in Supraglottic Ca Larynx

Introduction: To observe the association between the level of lymph node metastasis and the T- stage and to evaluate the N- stage in supraglottic carcinoma of larynx. Materials and Methods: A prospective cross-sectional study was carried out on 80 consecutive cases of supraglottic carcinoma larynx in three tertiary level hospital in Dhaka during July'2009 to March 2011. Results: The highest number of patients were in the age group 5th and 6th decades. Male to female ratio was 9:1. Topographically 70 cases (87.5%) had lesions involving epiglottis, 5 cases (6.25%) in aryepiglottic fold and 5 cases (6.25%) had lesions at false cord. Majority cases were histopathologically confirmed squamous cell carcinoma (95%) and among them 46 cases (57.5%) had well differentiated. Cervical metastatic lymph nodes were found 40% (32 cases) where level-II was most common. This was most frequent in early supraglottic(T1&T2) carcinoma of larynx (86.25%), P=0.008. A positive correlation was found between the T stage of primary tumours and frequency of cervical lymphadenopathy. Lymph node metastasis were 4.77% in T1, 37.50% in T2, 71.43% in T3 and 91.67% in T4. In early stage lymph node involved 93.75% in Level- II, 6.25% in Level- III & in advanced stage 100% in Level - II, 62.5% in Level - III and 25.0% in Level - IV. Distribution of study cases (31.25%) in stage-II, 25% in stage-I, 22.50% in stage-Ill and 21.25% were in stage-IV. Conclusion: Result of this study may help the clinician for planning of treatment of this malignant diseases as well awareness. Medicine Today 2019 Vol.31(2): 72-75