scholarly journals Clinicopathological Study of Supraglottic Carcinoma of Larynx

2020 ◽  
Vol 15 (2) ◽  
pp. 224-226
Author(s):  
Md Monsur Alam ◽  
Md Zakir Hossain ◽  
Mohd Shamim Bin Shaid Khan

Introduction: Incidence of supraglottic carcinoma is more common which may be related to poor nutrition with personal habit like smoking and chewing habit of betel leaves with various ingredient. Objectives: To find out the incidence, age and sex distribution, occupation and clinical presentation of supraglottic carcinoma of larynx. Materials and Methods: In this prospective study, 30 patients of supraglottic carcinoma are collected from department of ENT and Head-Neck surgery, Combined Military Hospital, Dhaka from July 2012 to July 2013. Results: Patients belongs to different age groups, ranging from 40 to 80 years and maximum patients are in 50 to 60 years of age. The male to female ratio is 5:1. In this series, majority of patients are smoker (66.66%). Most of them are from low socio-economic group. The incidence of lymph node involvement is 40% (12 cases). Maximum number of patients presents with exophytic lesion (60%). Ulcerative lesions are 26.66% and infiltrative lesions are 13.33%. Maximum numbers of patients have T2 lesions (80%). T1 lesions are 20%. In this study all cases are histopathologically confirmed to be squamous cell carcinoma (100%). In this study, all cases are M0 state. Conclusion: Supraglottic carcinoma occurs between 40-80 years of age, more common in 5th and 6th decades. Chewing betel nut and tobacco should be avoided to reduce the risk of supraglottic carcinoma and early presentation & diagnosis will improve the prognosis of patients. JAFMC Bangladesh. Vol 15, No 2 (December) 2019: 224-226

2019 ◽  
Vol 31 (2) ◽  
pp. 72-75
Author(s):  
Mohammad Rokan Uddin Bhuiyan ◽  
Mohammad Idris Ali ◽  
Balayet Hossain Siddiquee ◽  
Fatema Johora ◽  
Mohammad Kamal Hossain

Introduction: To observe the association between the level of lymph node metastasis and the T- stage and to evaluate the N- stage in supraglottic carcinoma of larynx. Materials and Methods: A prospective cross-sectional study was carried out on 80 consecutive cases of supraglottic carcinoma larynx in three tertiary level hospital in Dhaka during July'2009 to March 2011. Results: The highest number of patients were in the age group 5th and 6th decades. Male to female ratio was 9:1. Topographically 70 cases (87.5%) had lesions involving epiglottis, 5 cases (6.25%) in aryepiglottic fold and 5 cases (6.25%) had lesions at false cord. Majority cases were histopathologically confirmed squamous cell carcinoma (95%) and among them 46 cases (57.5%) had well differentiated. Cervical metastatic lymph nodes were found 40% (32 cases) where level-II was most common. This was most frequent in early supraglottic(T1&T2) carcinoma of larynx (86.25%), P=0.008. A positive correlation was found between the T stage of primary tumours and frequency of cervical lymphadenopathy. Lymph node metastasis were 4.77% in T1, 37.50% in T2, 71.43% in T3 and 91.67% in T4. In early stage lymph node involved 93.75% in Level- II, 6.25% in Level- III & in advanced stage 100% in Level - II, 62.5% in Level - III and 25.0% in Level - IV. Distribution of study cases (31.25%) in stage-II, 25% in stage-I, 22.50% in stage-Ill and 21.25% were in stage-IV. Conclusion: Result of this study may help the clinician for planning of treatment of this malignant diseases as well awareness. Medicine Today 2019 Vol.31(2): 72-75


2020 ◽  
Vol 5 (5) ◽  
pp. 242-247
Author(s):  
A. K. Khudyk ◽  

Currently, fractures of the middle face area remain a serious problem of maxillofacial traumatology because there is not only an increase in the number of injuries to the bones of the facial skull, but also the sever character of these injuries, and an increasing number of post-traumatic complications. This is due to the increase in crime, alcoholism, the proliferation of weapons among the population, the increase in traffic accidents, and injuries in the war zone. The purpose of the study was a retrospective analysis of the features of the damage to the middle face area of patients in a large industrial region. Material and methods. We conducted a retrospective analysis of the injury features of the middle face area in 416 patients who became patients of the department of head and neck surgery for the period from January 1, 2010 to December 31, 2019. Results and discussion. The study results showed that the vast majority (χ2 = 529.9; F = 0.000000; p <0.05) of patients were male. Men had by 79.3 (OR = 79.29; F = 0.000000) times higher risk of middle face injury than women. The risk of traumatic face injury in women increased with the age. Thus, in the group of women aged 61+ it was by 29.6 times higher than in the group of women aged 21-30 (OR = 29.6; F = 0.003203). The greatest number of injuries was observed in the age group of 21-30 years. Assessment of the injury risk in this age group showed that it was by 35.5 times higher than in the group of patients aged 61+ and by 2.1 times higher than in the group aged 31-40. Conclusion. The main etiological factor of injuries of the middle face area was domestic trauma, which was 369 (88.7±1.5)% of cases, which was significantly more (χ2 = 498.5; F = 0.000000; p <0.05) than other types of injuries. The risk of domestic injury was by 61.6 times higher than other types of injury. The study results proved that criminal injuries had the highest frequency among all types of injuries (50% of all types of injuries), fall injury was on second place (38%), and road accidents injuries were on third place (7%). A significant majority of the middle face injuries had men, the number of women with injuries of the middle face area increased significantly with the age. The largest number of patients (71.4%) with injuries of the middle face area occurred in the age groups 21-30 and 31-40, that is people of working age


2021 ◽  
Vol 71 (3) ◽  
pp. 744-48
Author(s):  
Fayyaz Hassan ◽  
Khalil Ahmad ◽  
Saeed Bin Ayaz ◽  
Heyyan Bin Khalil

Objective: To determine the spectrum of findings in patients presenting for upper gastrointestinal (UGI) endoscopy and investigate role of age and gender. Study Design: Cross-sectional study. Place and Duration of Study: Department of Gastroenterology & Internal Medicine, Combined Military Hospital Kharian, from Jul 2017 to Mar 2019. Methodology: The data regarding 638 consecutive patients who underwent upper gastrointestinal endoscopy in the department were collected from the computer-based database and patients were stratified into two groups according to their age: ≤50 and >50 years. Results: The mean age was 50.2 ± 17.4 (range: 7-100) years. There were 431 males and 207 females. The commonest presenting complaint was decompensated chronic liver disease (CLD) 162 (25.4%). The upper gastrointestinal endoscopy was normal in 306 (48%) and abnormal in 332 (52%) patients. The commonest abnormality seen on upper gastrointestinal endoscopy was esophageal varices seen in 167 (26.2%) followed by non-specific gastropathy, and hiatal hernia seen in 28 (4.4%) and 21 (3.3%) patients respectively. No significant differences were observed among males and females for a positive upper gastrointestinal endoscopy. Significantly large number of patients of age >50 years had an abnormal upper gastrointestinal endoscopy (p<0.001). The commonest upper gastrointestinal endoscopic abnormalities were similar in both genders and age-groups. Conclusion: The commonest finding on upper gastrointestinal endoscopy were esophageal varices and non-specific gastropathies. Females and patients ≤50 years had a higher prevalence of a normal upper gastrointestinal endoscopy. The commonly observed upper gastrointestinal endoscopy findings were generally similar among the genders and the age-groups.


2021 ◽  
Author(s):  
Wenli He ◽  
Danhong Xu ◽  
Jiafeng Wang ◽  
Yuze Shen ◽  
Zheng Lin ◽  
...  

Abstract BackgroundLittle is known about the gender characteristics and the Corona Virus Disease 2019(COVID-19) impact on psychiatric department outpatients in general hospitals in China. MethodsWe retrospectively collected 225,947 outpatient clinic records before and during COVID-19 pandemic from January 1, 2019 to December 31, 2020 in the psychiatric clinic of 3 general hospitals, gender composition of patients was analyzed in different five age groups and nine diagnostic categories at three levels: total patient visits, number of patients and number of first-visit patients. ResultsThe total male-to-female ratio of psychiatric outpatient records in 3 general hospitals from 2019 to 2020 was 1:1.69. Women were more common in all age groups and the male-to-female ratio of 2020 was expanded compared to that of 2019, especially in age group below 34 years old and anxiety disorders category. Most mental disorders showed higher demands for females than that for males except Mental and behavioral disorders due to psychoactive substance use with the male-to-female ratio was 1:0.05. Compared to 2019, the proportions of women were expanded especially in age group below 34 years old, and anxiety disorder and undetermined diagnosis categories were significantly increased in 2020. ConclusionsThe demand for female psychiatric outpatient services is obviously higher than that for males. It is necessary to pay more attention to explore targeted mechanism or psychosocial service strategy for female patients with mental disorders. Trial registration: ChiCTR2100044894, March 31,2021 retrospectively registered.


2011 ◽  
Vol 18 (02) ◽  
pp. 215-221
Author(s):  
MUHAMMAD ALI ◽  
TAHIR IQBAL MIRZA ◽  
RIAZ AKHTAR

Objective: To compare lateral anal sphincterotomy (closed method) with anal dilatation in the management of primary chronic anal fissure. Study design: A prospective, comparative, interventional study. Place and duration: Department of Surgery Combined Military Hospital Kohat from Jan 2001 to Mar 2002.Materials and Methods: During the period, all patients with primary type of chronic anal fissure, who were above 12 years of age and were fit for surgery, were selected for study. They were divided into two groups for both surgical procedures in a randomized manner. After their respective surgical procedures patients were followed up for four weeks on weekly basis. The changes in signs and symptoms were thoroughly reassessed and noted in a separate proforma maintained for each patient for the purpose of comparison. Results: The total number of patients was 49 with an average age of 40 years. Male to female ratio was 7:1. In 44 (89.79%) patients the fissure was located posteriorly while in 5 (10.20%) patients it was located anteriorly. Closed lateral anal sphincterotomy (LAS) was done in 28 (57.14%) patients, of which 25 (51.02%) were males and 3 (6.12%) females. While anal dilatation (AD) was done in 21 (42.85%) patients, 18 (36.73%) males and 3 (6.12%) females. In all the patients in whom LAS was done, there was disappearance of all the symptoms and complete healing of ulcer. Those operated by AD, there was disappearance of all the symptoms and complete healing of ulcer in only 8 (38%) patients. Incontinence was present in 9 (18.36%) patients. Three (14.2%) patients had persistence of ulcer while one (4.76%) was having recurrence of ulcer.Conclusion: Lateral anal sphincterotomy, especially close method gives excellent results as compared to anal dilatation in terms of ulcer healing, disappearance of symptoms and lower rate of ulcer recurrence or incontinence. 


1970 ◽  
Vol 16 (2) ◽  
pp. 106-112
Author(s):  
Md Anwar Hossain ◽  
SM Tareq Uddin Ahmed ◽  
Md Monjurul Alam ◽  
Kamrul Hassan Tarafder ◽  
Abu Hena Mohammad Parvez Humayun

Objectives: To find out the presentation of supraglottic carcinoma of larynx.Methods: Fifty cases of supraglottic carcinoma were selected from the in-patient department of Otolaryngology and Head-Neck surgery of Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka, during March, 2009 to August, 2009.Results: Among 50 cases in this study male: female ratio 11.5:1 and mean age was 55 years with range 35 years to 80 years. Majority of cases were from the lower socioeconomic group (66%). Regarding habit 94% were smoker, 60% were habituated with chewing betel leaf and betel nuts with or without other ingredient. Only 3 cases (6%) were alcoholic. Most of the cases presented with more than one symptoms and commonest symptoms was change of voice (82%) which was followed by dysphagia (76%), respiratory distress (54%) and neck swelling (42%). 32 (64%) cases had enlarged cervical lymph nodes out of which 27 (84.37%) were homolateral, 4 (12.50%) were bilateral and only 1 (3.12%) was contra-lateral. Vocal cord movement was normal in 23 (46%) cases, impaired in 12 (24%) and fixed in 15 (30%) cases. Most of the cases presented with exophytic lesion 34 (68%) where ulcerative lesion was 16 (32%). (52%) presented with involvement of arytenoid with aryepiglottic folds/vestibule of larynx, 12 cases (24%) had lesion at epiglottis with vestibule/aryepiglottic folds, 8 cases (16%) had lesion at vestibule with false cord, 4 cases (8%) had lesion involving the epiglottis only. Maximum number of patients had T3 lesion (44%) and T2 lesion was 36%. Most of the cases presented at an advanced stage, stage- IV was 42% and stage- III was 36%. Stage- I and stage- II were 6% and 16% respectively. Conclusion: Most common presenting symptoms of supraglottic carcinoma were change of voice, dysphagia and respiratory distress and most of the cases prented in an advanced stage (Stage III and Stage IV). Key words: Supraglottic; personal habit; neck node DOI: 10.3329/bjo.v16i2.6845Bangladesh J Otorhinolaryngol 2010; 16(2): 106-112


Author(s):  
Mahdi M Al-Thuwaini ◽  
Sabah H Enayah ◽  
Mohammed Abdul Azeez Ali Alwzy ◽  
Alyaa Abed_Al Husieen Hafeh

Background: Transitional cell carcinoma (TCC) of the bladder is the second most common malignancy of the genitourinary tract and the third most common cause of death among people with genitourinary tumors, besides, tumors of the bladder are an important source of both morbidity and mortality. Objectives: The purpose of the study are 1. formulate an idea about the number of patients with bladder cancer (TCCs) in sample of Iraqi population. 2. Study the histopathological features of TCCs of bladder 3. Assessment the prevalence of (TCC) of bladder in both sex (male and female) with smoking as risk factor. Patients and Methods: A study was conducted at one institution were identified that teaching-hospital of Baghdad. All patients included in the present study diagnostic with TCC of bladder. The total of subjects participated in the study were 42 patients and 20 subjects as control through six months’ period from July 2014 to January 2015. Results: The mean of participates age was 655.7 years and the youngest was 21years and the oldest was 75 years. Out of 42 patients, the most common age group was 54-64years (52.38%) with Male to female ratio was 5.2:1.32 were male 32 and 10 were females. However, the prevalence bladder cancer (TCCs) was higher in male than in female, with more pronounced decreases in younger age (≤31year) 3(7.14), have been found. In addition, age specific rate was observed higher in the older age groups for most patients with cancer. The population attributable risk for ever smoking in our study was 33(78.57) out of 42 patients. Moreover, current study shows there was a correlation between grade and stage of bladder TCC, 24(57.14%) bladder TCCs that classified as grade I, while 2(4.76%) of bladder TCC were classified as grade II. Conversely, of the bladder TCC lesions (11.9%, 14.28%, 57.14 and 4.76) were stage (pTa-T1-T2-T3) respectively. Although this study showed 5(11.9) little-known stage and grade. The area of histopathological changes included were showed hyperplastic changes, involving the entire bladder lining, that ranged from flat hyperplasia to small areas of nodular and papillary hyperplasia. The smallest recognizable nodular and papillary lesions were associated with angiogenesis in the contiguous stroma. In addition, there were chromatin irregularities and nucleoli of variable numbers, shape and size. Nuclear chromatin irregularity and mitoses were easily identified, these cells continued to have the appearance of hyperplastic epithelium. The changes noted by generalized and orderly proliferative reaction and appeared reparative. Conclusions: Our study has revealed that the bladder TCC, where appeared the high prevalence and incidence rate of TCC of bladder in sample of Iraqi population were of concern, especially for older age groups.


2019 ◽  
Vol 16 (1) ◽  
pp. 21-24
Author(s):  
Balgopal Karmacharya ◽  
Nikunja Yogi ◽  
Benju Pun

The aim of this determine the causes, frequency, location of isolated extradural hematomas in patients presenting with head injury and to find out the outcome of surgery in such patients. This is prospective observational study was conducted in the Neurosurgery Unit of Manipal Teaching Hospital from January 2012 to January 2017. All patients who presented with headinjury and had isolated extradural hematomas were included in the study. Total number of patients admitted with diagnosis of extradural hematomas during that time period was 169 among which 94 patients underwent surgical treatment. Descriptive statistics data including age, gender, causes of injury, severity of head injury and Glasgow outcome scale were studied. Results in proportion and percentages were calculated by using Microsoft Excel 2013. There were 169 patients who had isolated extradural hematomas. Among them, 75 patients were managed conservatively and 94 underwent craniotomy for evacuation of hematoma. This group of 94 patients who operative treatment was taken for this study. Male: female ratio was 1.6:1. Mean age was 23 years. Most of patients were in 20-40 age groups. Causes of extradural hematomas included motor vehicle accidents, falls and assaults. Mild and moderate head injury was present in 53 (56.38%) and 32 (34.0%) patients. Seventy nine patients (84.05%) of patients had good recovery while 3 (3.19%) patients expired.


2017 ◽  
Vol 145 (1-2) ◽  
pp. 38-42
Author(s):  
Milan Jovanovic ◽  
Vladan Zivaljevic ◽  
Aleksandar Diklic ◽  
Nikola Slijepcevic ◽  
Katarina Tausanovic ◽  
...  

Introduction/Objective. Adrenocortical carcinomas (ACCs) are very rare tumors with grave prognosis despite multimodal treatment. The aim of our study was to determine the incidence and mortality of ACCs in Central Serbia. Methods. The study period was from 1999 to 2012. We used data from the Cancer Registry of Central Serbia. Incidence and mortality rates were sex- and age-standardized according to Segi?s world population. Results. In the defined period of the study, 128 patients with a diagnosis of ACC were registered and the female-to-male ratio was 1.3:1. The median age of affected individuals was 42.3 years. There were two main age peaks ? one in childhood (0?9 years), and the other in the fifth and sixth decade of life. In this period, the average standardized incidence rate of ACC amounted to two per million people with slightly increasing trend. The largest number of male patients with ACC (22; 39.2%) was registered in the age group of 0?9 years, while the largest number of patients in females was shown to be in the age group of 40?49 years (29; 40.3%). During the study period, there were 35 deaths registered in patients with ACC (mean age of 61.2 years). The average mortality rate of ACC was 0.3 per million people. The male-to-female ratio was 1.5:1. Most fatal outcomes were registered in the age groups of 50?59 and 60?69 years, so 91.4% of all deaths took place in the age groups 50+. Conclusion. ACC is an extremely rare tumor that occurs more often in women than in men. However, fatal outcomes occur more frequently in males.


1970 ◽  
Vol 18 (2) ◽  
pp. 80-83
Author(s):  
MA Jafor ◽  
M Latifur Rahman ◽  
S Hoque

This is a prospective study carried out at the department of surgery, Dhaka Shishu Hospital during the period from 1st February 1997 to 28th February, 1999. Fifty peadiatiric patients aged less than 12 yrs with provisional diagnosis of intussusception were included in this study. Highest number of patients were within 1 year of age (70%), male female ratio was 2.57:1, the exact aetiology of intussusception could not be indentified in majority of the cases (90%). Abdominal pain (82%), vomiting (78%) and per rectal bleeding (62%) was common presentations. All patients were managed surgically. Ileocolic type was commonest type of intussusception (66%). Postoperative complications was noted in 14% cases. With limited resources, this study tried to collect many information about various aspect of intussusception in Bangladeshi children. It is hoped that organization and compilation of these information will stimulate further studies, leading to a greater comprehension of the problems of intussusception of paediatric age groups in our country.   doi: 10.3329/taj.v18i2.3171 TAJ 2005; 18(2): 80-83


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